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Nov 16, 2018 - Conclusion: SLE-AIN is a seldom-recognized manifestation of lupus nephritis. ... PRESENTING WITH EXTENSIVE LONGITUDINAL MYELITIS.


018. A CASE OF SYSTEMIC LUPUS ERYTHEMATOSUS PRESENTING WITH EXTENSIVE LONGITUDINAL MYELITIS AND CEREBRAL VASCULOPATHY Hoda Neydani Tarakmeh and Dev Pyne Rheumatology, Bart’s Health Trust, London, UNITED KINGDOM Background: Neuropsychiatric SLE (NPSLE) affects 60% of patients with lupus. It usually occurs in active disease. The ACR established 19 definitions for NPSLE. Myelopathy is a rare form of NPSLE. Here we describe a case of a young patient presenting with acute extensive longitudinal myelopathy (AELM) and cerebral vasculopathy as a first manifestation of SLE. Methods: A 35-year old female patient presented to our hospital with history of lethargy, weight loss and night sweats for 3 months. She noticed lumps in her neck with difficulty passing urine and leg weakness for 8 weeks. She was 4 months post-partum. She had previous cardiomyopathy with LVEF of 35%. On presentation, she was febrile, had cervical and axillary lymphadenopathy with urinary retention. The neurological examination showed a power of 4/5 on the lower limbs bilaterally with brisk tendon reflexes, extensor plantar responses and no sensory deficits. Her motor power deteriorated over 10 days to 0/5. Results: Her laboratory workup showed Hb 79, WBC 2.5 (Neut 1.6, Lymph 0.8), Plt 413 and an inflammatory acute phase response (ESR 134mm/hr, CRP