to increase during pacing (PRE-RVEDV 248, 249, 271,257 mL; PRE-. RVESV: 193, 203, 234, and 233 mL at respectively 80, 100, 120, and. 140 bpm), whereas ...
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Poster Display IL Pacing for heart failure
Sunday, 13 June 2004
201 Is the clinical response to cardiac resynchronisation therapy in heart failure patients equal in patients with and without a previous pacemaker? D. Gras I , P.T. Mortensen s, W. Reiser 3, C. Linde 4, H.J. Bruns s , V. Mahaux 5, B. Stegemann5 on behalf of InSync III Investigator
1Nouvelles Cliniques Nantaises, Cardiology, Nantes, France; 2Skejby Hospital Aarhus University, Cardiology, Aarhus, Denmark; 3Cardio Clinic, Cardiology, Nurnberg, Germany; 4Karolinska Hospital, Cardiology, Stockholm, Sweden; 5Bakken Research Centre, Heart Failure Management, Maastricht, Netherlands Aim: Cardiac resynchronization therapy (CRT) using bi-ventricular pacing is an emerging treatment for patients (pts) with severe heart failure and ventricular dyssynchrony. The aim of this study was to assess the beneficial effect of CRT in patients (pts) with and without previously implanted bradycardia pacemakers (PM). Methods: The InSyncIII study enrolled heart failure pts in NYHA IIIV, LVEF130 msec for unpaced and > 180 ms for paced pts. NYHA class, 6-rain walk distance (6MWT) and rain of daily physical activity recorded by an activity sensor at baseline and at the 3-month follow-up were compared between the PM and the non-PM groups. Results: 88 pts with complete baseline and 3-month follow-up data were included into the analysis: 18/88 pts had a previous PM due to AVblock I (2), II (2), HI (9) and SSS (5). Except for QRS width baseline characteristics did not differ between groups. At 3-month vs baseline the 6MWT increased significantly more in the PM compared to the non-PM group (152.2-t-98.8 vs. 67.2:t:91.9 m, p
