May 22, 2018 - KA Alharbi, Zain Sharif, WA Ashram, Maher V - Dept. of Cardiology, Tallaght Hospital, Dublin, Ireland. IDA. Iron Storage Status at Both Study ...
including the World Congress on Acute Heart Failure
26 - 29 May Single Centre Audit of Experience in Tallaght Hospital among Patients with Chronic Heart Failure and Iron Deficiency Anemia (IDA). KA Alharbi, Zain Sharif, WA Ashram, Maher V - Dept. of Cardiology, Tallaght Hospital, Dublin, Ireland. Introduction • Chronic heart failure is a common condition and is significantly projected to increase in the coming years due to increased survival of patients with coronary artery disease. • Iron deficiency anemia is a commonly present co-morbidity in patient with heart failure and it has been associated with increased mortality and a poorer quality of life. Symptoms related to iron deficiency anemia are not specific and is considered as a major contributor to exercise intolerance even in the absence of anemia.
Purpose • The main purpose of this audit is to further characterize patients with chronic heart failure with iron deficiency anemia and normal iron storage irrespective of hemoglobin level in relation to the degree of kidney function, Pro BNP level and left ventricular systolic function.
Methods and results • We reviewed 133 patients with chronic heart failure in Tallaght Hospital, Dublin, Ireland in 12 months period of time from June 2016 until July 2017. The age range was between 39 and 94 with mean of 71 years. 88 patients were males and 45 patients were females. • Patients with iron profile (94 patients (70%) out of 133) split into 2 groups. Interestingly, two groups were almost equal in number (46 patients with IDA and 48 patients with normal iron storage) • Comparing 2 groups in relation to kidney function, Pro BNP level and left ventricular systolic function showed significant difference in Pro BNP level between 2 groups (Pro BNP was elevated in 84.78% of IDA patients with HF while only 12.5% of HF patients with normal iron storage there Pro BNP was elevated). Both groups showed > 90% of patients have stage 2 to stage 5 CKD. In relation to left ventricular systolic function, 50% of patients at each group showed severely reduced systolic function.
Conclusion • IDA is a significant exacerbating factor of heart failure which is strongly correlated “in particular” to raise Pro BNP level “as a HF exacerbation- biomarker “ comparing to patients with normal iron storage. There is no much difference in both groups regarding kidney function and left ventricular systolic function. In fact at both study groups almost half of patients were have severely reduced LVEF with significant impairment in kidney functions. • Therefore, checking iron profile in patients with high level of Pro BNP and heart failure exacerbation will have an excellent impact on patients’ wellbeing and eventually reducing the burden on health care system.
Raised Pro BNP Level in Correla on to Study Groups Popula on
