786 Acute coronary syndromes

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Oct 16, 2018 - high risk of death within two years after acute coronary syndrome ... fusion and Dressler syndrome are the major pericardial complications after ...
786

Acute coronary syndromes

cardiac rupture in this study was comparable with previous reports. Early revascularization by PCI could be a possible factor of this result.

year death (HR 2.95, 95% CI 2.46–3.54), as was a more recent period of enrollment (HR 2010 vs 1995: 0.50, 95% CI 0.42–0.58) Conclusion: Although the incidence of HAVB is low and decreasing, this complication continues to be associated to decreased long-term survival. Improvement in outcomes over time in less in patients with HAVB. Acknowledgement/Funding: French Society of Cardiology, funded by unrestricted grants from Pfizer and Servier, and an additional grant from the CNAM

Kaplan-Meier curve for all-cause death.

Conclusion: The rate of cardiac rupture was low in spite of older age of AMI patients in this study. Early and successful revascularization may play a key role in lowering the rate of cardiac rupture.

P3644 | BEDSIDE High-grade atrioventricular block in acute myocardial infarction: evolution of prevalence, patient profile, management and outcomes, 1995-2010. Insights from FAST-MI Registries N. Aissaoui 1 , E. Puymirat 1 , Y. Juilieres 2 , P. Jourdain 3 , D. Blanchard 4 , F. Schiele 5 , P. Gueret 6 , J. Ferrieres 7 , T. Simon 8 , N. Danchin 1 . 1 AP-HP - European Hospital Georges Pompidou, Paris, France; 2 Hospital Brabois of Nancy, Vandoeuvre les Nancy, France; 3 Rene Dubos Hospital Center, Pontoise, France; 4 Clinique St Gatien, Tours, France; 5 University of Besançon, Besançon, France; 6 University Hospital Henri Mondor, Creteil, France; 7 Toulouse Rangueil University Hospital (CHU), Toulouse, France; 8 Hospital Saint-Antoine, Paris, France Background and aim: High-grade atrioventricular block (HAVB) is a fearsome complication in patients with acute coronary syndromes (ACS). Prior studies have reported the incidence of HAVB in ACS between 3 and 14% with an associated three to five-fold increased risk of in-hospital death. Data on the prognostic impact of HAVB complicating ACS on long-term mortality and changes in outcomes over the past 15 years are scarce. We assessed key features, variations in early and long-term mortality from HAVB complicating ACS and predictors of death over the past 15 years by analysing data from the 4 nationwide French registries USIK (1995), USIC 2000, and FAST-MI (2005 and 2010). Methods: The clinical characteristics, in-hospital therapies, and outcomes were compared between patients with and without HAVB. Factors associated with one year death in the whole population were determined. Results: Among the 10,610 patients of the 4 nationwide French registries, 364 patients (3.4%) developed HAVB; 294 (80.8%) complicating STEMI and 70 (19.2%) NSTEMI. From 1995 to 2010, prevalence of HABV decreased from 6.7% to 2.0%. Compared to non-HAVB patients, HAVB patients were older (73±12 vs 66±14 years), presented less often anterior STEMI. HAVB patients received less early recommended medications but more diuretics and inotropes; cardiac catheterization was less frequently performed. The percent of HAVB patients who received PCI or CABG during the hospital stay increased from 7.5% to 58.5%, and from 0.7% to 6.5%, P