A new Multimodal Indicator Design Integrating ...

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After skin incision, anesthetic doses were increased until EEG burst suppression (BS) occurred. (figure 1). Subsequently, anesthesia was performed according to.
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Technische Universität München

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A new Multimodal Indicator Design Integrating Standard Monitoring and Electroencephalographic Data for Quantification of “Depth of Anesthesia” rC re

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A multimodal integration of standard and EEG parameters significantly exceeds the performance of the current standard of “depth of anesthesia” monitoring. Included EEG analysis methods of AMI reduce influence of surrogate muscle activity in EEG as well as index calculation time. These improvements should lead to a more reliable detection of awareness, thereby reducing the risk of memory recall.

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[1] Anesthesiology 2006; 105: A1553 [2] IEEE Trans Syst Man Cybern 1993; Vol. 23, No. 3 [3] Anesthesiology 2007; 107: 397405 [4] Anesthesiology 2008; 109: 1014-22 [5] Anesth Analg 2007; 104: 135-9

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The AMI showed PK of 0.93 (CI: 0.92-0.94) for separation of different levels of anesthesia (wakefulness to EEG burst suppression), whereas BIS has a significantly lower PK of 0.80 (0.78-0.81). At the transition between consciousness and unconsciousness (LOC and ROC) AMI yields PK of 0.85 (0.820.87), which is significantly higher than PK of 0.74 (0.71-0.77) for BIS (threshold p