10/3/2014
TTP 8 & STVM
ABSTRACT SUBMISSION
Title: Are wild ruminants a relevant node in Coxiella burnetii maintenance and transmission? The role of red deer (Cervus elaphus) in the Iberian Peninsula. Abstract No.
0024
Title
Are wild ruminants a relevant node in Coxiella burnetii maintenance and transmission? The role of red deer (Cervus elaphus) in the Iberian Peninsula.
Objectives
Method
Conclusions
The implication of wildlife in Coxiella burnetii - the causal agent of Q fever - ecology has been largely dismissed. C hanges in red deer population dynamics may change their relevance as C. burnetii reservoirs for livestock and/or humans. We analysed the rate of exposure to C. burnetii and shedding, and investigated the clinical outcome of Q fever in red deer in the Iberian Peninsula.
1,486 red deer sera were analysed by ELISAC OXLS (ThermoFisher Scientific, USA); 14.1% (95% C onfidence Interval (C I): 12.3-15.9) were positive. Risk factor analyses revealed the influence of geography, population, management, cattle density, age and sex on deer exposure to C. burnetii. In a C. burnetii endemic deer farm serum and vaginal swabs from hinds, either experiencing or not reproductive failure, were tested by ELISA and PC R. Coxiella burnetii antibody and DNA prevalence differed in hinds with reproductive failure (50% 95%C I: 21.7-78.3 - and 40% - 95%C I: 9.7-70.3, respectively) with respect to hinds calving normally (23.1% - 95%C I: 0.0-46.0 - and 15.4% - 95%C I: 4.2-35.0, respectively).
The high seroprevalence (>30%) observed in some Iberian red deer populations and proven vaginal shedding suggest that deer play an important role in active transmission of C. burnetii at the wildlife/livestock/human interface in Iberia, and perhaps in the Northern Hemisphere. Q fever may additionally be an important cause for reproductive failure in red deer. On-going genotyping of C. burnetii strains from red deer and other Iberian wildlife will clarify the extent of wildlife/livestock/human transmission events.
Approval
C onfirm
Affiliations
(1) Spanish Wildlife Research Institute, C iudad Real, C astilla - La Mancha, Spain (2) Departament of Biology & C ESAM, University of Aveiro, Aveiro, Portugal (3) C IBIO / InBio / FC UP, Universidade do Porto, Vairão, Portugal
Authors
David González-Barrio João P.V. Santos João Queiros Mariana Boadella José Ángel Barasona Beatriz Beltrán-Beck Francisco Ruiz-Fons
Registration
C onfirm
(1) Presenting (1) (2) (1) (3) (1) (1) (1) (1)
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10/3/2014
TTP 8 & STVM
Categories
2. Epidemiology, ecology and modelling for prevention and prediction.
Presentation
Oral
Website
Yes
Permission
Yes
Invitation
Yes
Conflict
No
Registration
C onfirm
Paper
González-Barrio et al. C. burnetii Iberian red deer.docx
Award
Yes
Author information
Email address
Phone number
Author 1
[email protected]
0034926295450
Author 2
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0034926295450
Author 3
[email protected]
0034926295450
Author 4
[email protected]
0034926295450
Author 5
[email protected]
0034926295450
Author 6
[email protected]
0034926295450
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