Adjunctive levetiracetam in infants and young ... - Wiley Online Library

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Oct 23, 2008 - partial-onset seizure frequency was 43.6% for levetiracetam and 7.1% for placebo with a median difference between treatment groups of 39.2%.

Epilepsia, 50(5):1141–1149, 2009 doi: 10.1111/j.1528-1167.2008.01981.x

FULL-LENGTH ORIGINAL RESEARCH

Adjunctive levetiracetam in infants and young children with refractory partial-onset seizures *Jesus Eric Pin˜a-Garza, yDouglas R. Nordli Jr, zDietz Rating, xHaichen Yang, xJimmy Schiemann-Delgado, and xBenjamin Duncan; on behalf of the Levetiracetam N01009 Study Group1 *Children’s Hospital at Vanderbilt, Nashville, Tennessee, U.S.A.; yChildren’s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, U.S.A.; zEpilepsy Centre Children’s Hospital, University of Heidelberg, Heidelberg, Germany; and xUCB Inc, Smyrna, Georgia, U.S.A.

SUMMARY Purpose: To evaluate the efficacy and tolerability of adjunctive levetiracetam in very young children (aged 1 month to

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