Alginates

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Alginates

Available March 2019

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Versatile Polymers in Biomedical Applications and Therapeutics Editors: Md Saquib Hasnain, PhD Shri Venkateshwara University, Gajraula, Amroha, U.P, India

Amit Kumar Nayak, PhD Associate Professor, Seemanta Institute of Pharmaceutical Sciences, Odisha, India

This new volume, Alginates: Versatile Polymers in Biomedical Applications and Therapeutics, explores the latest research on the use of alginates as a biopolymer in various biomedical applications and therapeutics. The biomedical and therapeutic uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for biomedical applications and therapeutics. Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals, as medical diagnostic aids, and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. These include liquid gels, powders, beads, films, tablets, capsules, microspheres, microparticles, nanoparticles, nanosponges, nanofibrils, and nanocomposites. A thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields needs to be thoroughly understood, and this volume offers an abundance of information toward that end. With chapters from experts in the field, this volume provides insight into the complete alginate chemistry, collection, chemical modifications, characterization, and applications of alginate in the healthcare field. The volume will be of interest to professors, researchers and early career young scientists in the disciplines of medical and pharmaceutical sciences, as well as drug delivery scientists, nanotechnologists and nanobiotechnologists, and scientists working in the disciplines of biomedical engineering and nanomedicine.

CONTENTS Preface 1. Alginates: Source, Chemistry, and Properties Mithilesh Yadav and Younes Ahmadi 2. Recent Advances of Alginates as Material for Biomedical Applications Milan Milivojevic, Ivana Pajic-Lijakovic, and Branko Bugarski 3. Alginates: Hydrogels, Their Chemistry, and Applications Verónica Elena Manzano, María Natalia Pacho, Joana Elisa Tasqué, and Norma Beatriz D’Accorso 4. Alginate-Based Hydrogels: Synthesis, Characterization, and Biomedical Applications Vandana Singh and Angela Singh 5. Chemically Modified Alginates for Advanced Biomedical Applications Ibrahim M. El-Sherbiny, Mostafa M. Abd Al Aziz, and Esraa A. Abdelsalam 6. Bionanocomposites of Alginates, Their Chemistry, and Applications Nancy L. García, Mario Contín, Carlos A. Rodriguez Ramirez, and Norma B. D’Accorso 7. Alginate and Its Applications in Tissue Engineering Dilshad Qureshi, Seemadri Subhadarshini, Suraj Kumar Nayak, Doman Kim, Preetam Sarkar, Indranil Banerjee, and Kunal Pal 8. Alginate-Based Scaffolds in Bone Tissue Engineering Applications S. Viji Chandran, V. Sanjay and N. Selvamurugan 9. Alginate: Properties, Pharmaceutical, and Tissue Engineering Applications Joshy K. S., Snigdha S., and Sabu Thomas 10. Alginate: Drug Delivery and Application Gautam Singhvi, Rapalli Vamshi Krishna, Kowthavarapu V. Krishna, and Sunil Kumar Dubey

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11. Chemical and Physical Modifications of Alginate to Improve Its Use as Carriers in Delivery Systems Gabriela Valladares, Karina Bierbrauer, and Miriam Strumia

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side 2

12. Updates on Alginate-Based Interpenetrating Polymer Networks for Sustained Drug Release Ibrahim M. El-Sherbiny and Kholoud Arafa 13. Alginate Nanoparticles Isra Dmour and Mutasem Taha 14. Alginate-Based Nanocarriers, Modern Therapeutics Vandana Singh and Angela Singh 15. Alginate-Based Composites in Drug Delivery Application Ankita Tiwari, Ankit Jain, Amit Verma, Pritish Panda, and Sanjay K. Jain 16. Hydroxyapatite-Alginate Composites in Drug Delivery Sitansu Sekhar Nanda, Dong Kee Yi, M Saquib Hasnain, and Amit Kumar Nayak 17. Alginate-Based Gastro-Intestinal Tract Drug Delivery Systems Sougata Jana, Kalyan Kumar Sen, and Sabyasachi Maiti 18. Alginate Hydrogels as Colon-Targeted Drug Delivery System Pramendra Kumar and Deepak Kumar 19. Alginate Carriers for Treatment of Ocular Diseases Ravi Sheshala and Tin Wui Wong 20. Alginate Carriers for Bioactive Substances: Herbal Natural Compounds and Nucleic Acid Materials Maria Rosaria Lauro, Giovanni Amato, Francesca Sansone, Claudia Carbone, and Giovanni Puglisi Index

646 pages with index.

ABOUT THE EDITORS Md Saquib Hasnain, PhD, has over six years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially in systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches as well as development and characterization of polymeric composites, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, HPLC, LC-MS, and many more. He has authored over 30 publications in various high-impact peer-reviewed journals, 30 book chapters, and one Indian patent application to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (H-Index: 12). He has also participated and presented his research work at over ten conferences in India and abroad. He is also a member of several scientific societies, including the Royal Society of Chemistry, Great Britain; International Association of Environmental and Analytical Chemistry, Switzerland; and Swiss Chemical Society, Switzerland. Amit Kumar Nayak, PhD, is currently an Associate Professor at the Seemanta Institute of Pharmaceutical Sciences, Odisha, India. He has over ten years of research experience in the field of pharmaceutics, especially in the development and characterization of polymeric composites, hydrogels, novel and nanostructured drug delivery systems, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, and HPLC. He has authored over 120 publications in various high-impact peer-reviewed journals and has 34 book chapters to his credit. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (H-Index: 28, i10-Index: 68). He has been the permanent reviewer of many international journals. He also has participated and presented his research work at several conferences in India and is a life member of the Association of Pharmaceutical Teachers of India (APTI). He has earned his PhD in Pharmaceutical Sciences from IIFTM University, Moradabad, U.P., India.

ISBN hard: 978-1-77188-782-3. Cat#: K406761. Ebook ISBN: 9780429023439. Cat#: KE70431 . $249.95 US | £193.00 hardback. March 2019.

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