5 Department of Oncology, Tawam Hospital, GAHS, Al-Ain, United Arab Emirates ... men [4,5] Furthermore, some study showed that colorec- ..... US$300.00.
Biomedical Research 2006; 17 (2): 149-154 Short communication
Amino acid profiles among colorectal cancer patients Abdulbari Bener 1,2, Muzeyyen Dogan 3, Ismail Abou Azab 4, Ali Rashed 5, Midhat Siddiqui 6 1
Department of Medical Statistics & Epidemiology, Hamad General Hospital, Hamad Medical Corporation Doha, State of Qatar 2 Department Evidence for Population Health Unit, School of Epidemiology and Health Sciences, The University of Manchester, Manchester, United Kingdom 3 Department of Chemistry, Faculty of Sciences, Yildiz Technical University, Istanbul, Turkey 4 Department of Surgery, Al-Ain Hospital, MOH, Al-Ain, United Arab Emirates 5 Department of Oncology, Tawam Hospital, GAHS, Al-Ain, United Arab Emirates 6 Department of Surgery, Queen Mary Hospital, NHS, London, United Kingdom Key Words: Epidemiology. Case-control. Colorectal cancer. Amino acid. UAE Accepted May 24 2006
Abstract The aim of this study is to determine the amino acid profile among the colorectal cancer patients. This is a prospective descriptive case-control study. This study includes 108 patients who underwent surgeries for colorectal carcinoma and 108 healthy control subjects during the period from1998 to 2003. The patients' data included: age, gender, pathological data and p53 expression. We performed the avidin-biotin complex immunoperoxidase method to detect bound p53 protein. An analysis with the Ion Exchange Chromatography was carried out for individual free amino acids. IgG antibodies against a low molecular weight fraction of H. pylori antigens were measured in duplicate with a validated in house indirect enzymelinked immunosorbent assay [ELISA]. Mean annual incidence was 3.1 patients / year. There were 74 males (68.5%) and 34 females (31.5%). The mean age at the time of diagnosis was 47.2 ± 9.7 years with the median age of 47 years. H. pylori serology was determined in all subjects. The sensitivity values for IgG and IgA H .pylori serology tests were 74% and 51% respectively (p 300 and > 250 respectively. The sensitivity values for IgG and IgA H .pylori serology tests were 74% and 51% respectively (p
