Amnitoic Membrane Transplantation for Ocular Surface Disorders -- ...
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Invest Ophthalmol Vis Sci 2002;43: E-Abstract 4195. © 2002 ARVO
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Amnitoic Membrane Transplantation for Ocular Surface Disorders
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Gopinathan1,A,
Sangwan1,B,
Honavar1,C,
U VS SG 1,D 1,D RS Kolari , S Tejwani , MS Sridhar1,B, AK Bansal1,B, GC Sekhar2, R Nutheti1,D and GN Rao1,B
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Ocular Oncology1 LV Prasad Eye Institute Hyderabad India Glaucoma and Oculoplasty Services LV Prasad Eye Institute Hyderbad India B Cornea and Anterior Segment Services A Jhaveri Microbiology Centre
Articles by Gopinathan, U
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Articles by Rao, G.
Commercial Relationships: U. Gopinathan, None; V.S. Sangwan, None; S.G. Honavar, None; R.S. Kolari, None; S. Tejwani, None; M.S. Sridhar, None; A.K. Bansal, None; G.C. Sekhar, None; R. Nutheti, None; G.N. Rao, None.
Articles by Gopinathan, U
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PubMed Articles by Rao, G.
Abstract Purpose:To analyze the indications and outcomes of amniotic membrane transplantation (AMT) for ocular surface disorders. Methods:Retrospective chart review of all patients who underwent AMT for ocular surface disorders in a tertiary eye care center between January 1998 and May 2001. Results:: In all, 360 patients (377 eyes) with median age 33 years (range 3 months to 86 years) were included. The median follow-up duration was 4 months. The major clinical conditions included pterygium (35%), chemical burns (18%), Stevens Johnson syndrome (9%), sterile epithelial defects (9%) and others (29%). The AMT was performed to initiate ocular surface reconstruction (71%), promote healing of epithelial defect (19%), alleviate stem cell deficiency (5%), and provide symptomatic relief (5%). The overall success rate was 68%. The best outcome was for surface reconstruction following excision of ocular surface squamous neoplasia (100%) and worst outcome was in cases with epithelial defect due to infectious etiology (50%). Repeat AMT was performed in 22% cases. On multivariate analysis the presence of symblepharon and infectious etiology were the factors predictive of poor outcome. Conclusion:Preserved human amniotic membrane transplantation seems to be safe and effective modality in the management of ocular surface disorders. However, in view of the sub-optimal results for some of the clinical conditions, stringent case selection is recommended. Keywords: 369 cornea: clinical science • 372 cornea: epithelium • 607 transplantation © 2002, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. For permission to reproduce any part of this abstract, contact the ARVO Office at
[email protected].
04-03-2015 14:47
Amnitoic Membrane Transplantation for Ocular Surface Disorders -- ...
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04-03-2015 14:47