S284
Asian Pac J Trop Biomed 2014; 4(Suppl 1): S284-S292
Asian Pacific Journal of Tropical Biomedicine journal homepage: www.apjtb.com
Document heading
doi:10.12980/APJTB.4.2014C1283
襃 2014
by the Asian Pacific Journal of Tropical Biomedicine. All rights reserved.
A ntiproliferative and hepatoprotective activity of metabolites Corynebacterium xerosis against Ehrlich Ascites Carcinoma cells
from
Farhadul Islam, Soby Ghosh, Jahan Ara Khanam* Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi 6205, Bangladesh
PEER REVIEW
ABSTRACT
Peer reviewer Dr. Zahangir Alam Saud, Professor, D epartment of B iochemistry and M olecular B iology, U niversity of Rajshahi, Bangladesh. E-mail:
[email protected]
Objective: To find out the effective anticancer drugs from bacterial products, petroleum ether extract of Corynebacterium xerosis. Methods: Antiproliferative activity of the metabolite has been measured by monitoring the parameters like tumor weight measurement, tumor cell growth inhibition in mice and survival time of tumor bearing mice, etc. Hepatoprotective effect of the metabolites was determined by observing biochemical, hematological parameters. Results: It has been found that the petroleum ether extract bacterial metabolite significantly decrease cell growth (78.58%; P
