Classical genetics involves the patterns of inheritance first described by Gregor ...
Complete AP Bio: Genetics Problems Worksheet featuring monohybrid and.
AP Biology Unit 6 – Classical Genetics Unit Classical genetics involves the patterns of inheritance first described by Gregor Mendel. We also look at some additional patterns not previously covered in regular biology. In addition, we will also look at some of the many diseases caused by the inheritance of specific genes. Last, we will look at gene frequencies in populations and how they are studied. Regarding the “big ideas” of AP Biology, this unit focuses on “Biological systems interact, and these systems and their interactions possess complex properties”. 1. Read “Human Genetics in a Nutshell”. Quiz on article 2. Read Chapter 13.1 (239-256) Patterns of Inheritance Complete AP Bio: Genetics Problems Worksheet featuring monohybrid and dihybid crosses.- ______________ Quiz: 13.1 3. Read the rest of Chapter 13 p 257- 273 (Omit section on “three point cross”) Complete More Genetics Problems Sheet - __________ Genetics Problems Quiz Blood Typing Lab 4. Pedigrees- Muscular Dystrophy -Huntington’s Disease Computer: http://learn.genetics.utah.edu/content/disorders/whataregd/ 5. Memorize the inheritance pattern and major symptoms for each of the following: Cystic Fibrosis Down Syndrome Sickle-cell anemia Turner Syndrome Tay-Sachs Klinefelter’s Phenylketonuria (PKU) Cri du chat Hemophilia Hypercholesterolemia Huntington’s Neurofibromatosis Duchene Muscular Dystrophy Robertsonian Translocation QUIZ on ________________ 6. Read Chapter 20: Genes within Populations p 421-437. AP LAB#8 “Population Genetics” QUIZ on ______________
*Work monohybrid, dihybrid and Hardy-Weinberg problems *Discuss Mendel’s work and his laws. *Define all relevant vocabulary (including but not limited to); Homo/heterozygous Geno/phenotype Alleles Multiple alleles Epistasis Continuous variation Pleitropy Polygenic Incomplete dominance Co-dominance Environmental effects Pedigree Karyotype Nondisjunction Antigen, Antibody Agglutinogen, Agglutinins, Agglutination *State the pattern of inheritance, molecular basis for disorder and symptoms/physiological effect of: Cystic Fibrosis, Sickle-Cell Anemia, Tay-Sachs, Phenylketonuria (PKU), Hemophilia, Huntington’s, Duchene Muscular Dystrophy, Down Syndrome, Klinefelter syndrome, Turner syndrome, Cri du chat, and William’s Syndrome. *“Read” a karyotype and determine the disorder *Explain the use of amniocentesis, chorionic villi sampling, pedigree and karyotype in genetic counseling *Recognize gene interaction and its effect on inheritance patterns; multiple alleles, epistasis, continuous variation, pleitropy, incomplete dominance, co-dominance, sexlinkage, environmental effects *State the five assumptions to maintain a constant allele frequency (Hardy-Weinberg) and explain how mutation, genetic drift, non-random mating and selection (3 types) affect the allele frequency. Be able to calculate the frequency of alleles using HardyWeinberg.
