Applied Microbiology and Biotechnology

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Institute of Biotechnology and Food Science, Faculty of Chemical and Food ... of Chemistry, University of Manchester, Manchester Institute of Biotechnology, 131.
Applied Microbiology and Biotechnology Supplementary Information

Immobilised whole-cell recombinant monoamine oxidase biocatalysis Petra Zajkoska1, Michal Rosenberg1, Rachel Heath2, Kirk J. Malone2, Radek Stloukal3, Nicholas J. Turner2, Martin Rebroš1* 1

Institute of Biotechnology and Food Science, Faculty of Chemical and Food Technology,

Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia 2

School of Chemistry, University of Manchester, Manchester Institute of Biotechnology, 131

Princess Street, Manchester M1 7DN, UK 3

LentiKat´s a.s., Evropská 846/176a, 160 00 Prague 6, Czech Republic

*Corresponding author: e-mail: [email protected], phone: +421 (2) 59 325 480, fax: +421 (2) 52 967 085

Figure S1. Telaprevir

Figure S2. Scheme for forming 3,4-substituted prolines using MAO-N desymmetrisation

Figure S3. The biotransformation of 3-azabicyclo[3,3,0]octane to 3-azabicyclo-[3,3,0]oct-2ene catalysed by MAO-N D5