Applied Microbiology and Biotechnology Supplementary Information
Immobilised whole-cell recombinant monoamine oxidase biocatalysis Petra Zajkoska1, Michal Rosenberg1, Rachel Heath2, Kirk J. Malone2, Radek Stloukal3, Nicholas J. Turner2, Martin Rebroš1* 1
Institute of Biotechnology and Food Science, Faculty of Chemical and Food Technology,
Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia 2
School of Chemistry, University of Manchester, Manchester Institute of Biotechnology, 131
Princess Street, Manchester M1 7DN, UK 3
LentiKat´s a.s., Evropská 846/176a, 160 00 Prague 6, Czech Republic
*Corresponding author: e-mail:
[email protected], phone: +421 (2) 59 325 480, fax: +421 (2) 52 967 085
Figure S1. Telaprevir
Figure S2. Scheme for forming 3,4-substituted prolines using MAO-N desymmetrisation
Figure S3. The biotransformation of 3-azabicyclo[3,3,0]octane to 3-azabicyclo-[3,3,0]oct-2ene catalysed by MAO-N D5