Applied the filter pretreated with berberine for removal

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using the herbal medicine-coptidis rhizoma extract. (berberine) and to explore the filtration efficiency of bioaerosols. Many studies have demonstrated that.

Cite abstract as Author(s) (2009), Title, European Aerosol Conference 2009, Karlsruhe, Abstract T077A12

Applied the filter pretreated with berberine for removal of bioaerosols S.H. Yang1, Y.C. Huang2, C.H. Luo3 and C.Y. Chuang4 1

Department of Environmental and Occupational Health, Toko University, Chia Yi County 613, Taiwan, R.O.C 2 Graduate Institute of Environmental Engineering, National Taiwan University, Taipei 106, Taiwan, R.O.C 3 Department of Environmental Engineering, Hung-Kuang University, Taichung County 433, Taiwan, R.O.C. 4 Department of Bio-lndustrial Mechatronics Engineering, National Taiwan University, Taipei 106, Taiwan, R.O.C. Keywords: filtration efficiency, bioaerosols, berberine, antiseptic bioaerosols through the untreated filter and the 1.0% berberine-pretreated filters are around 65% and 24%, respectively. A comparison of the results of the penetration of the PSL aerosol through the 1.0% berberine-pretreated filters indicates that penetrations of the E. coli bioaerosol and the PSL aerosol through the untreated filter were similar, while penetration through the 1.0% berberine-pretreated filters with E. coli bioaerosol were much lower than that with PSL aerosol, indicating that berberine has an antiseptic effect on E. coli bioaerosol.

100 90

1.0 mm PSL aerosol

E. Coli 80 70

Penetration (%)

Most people typically spend around 87.2% of their time indoors (Lance, 1996). Accordingly, indoor air quality is an increasingly important issue. Bioaerosols importantly affect indoor air quality because they cause various respiratory diseases (Eduard et al., 1993; Melbostad et al., 1994). Higher concentrations of bioaerosols were found in indoors because of higher temperature and relative humidity all round year in Taiwan. Many epidemiological studies have inferred that sick building syndrome (SBS) was related to bioaerosols. Therefore, it cannot be neglected that the problem of indoor air pollution caused by bioaerosols in Taiwan. The purpose of this study is desired to develop of antiseptic filters by using the herbal medicine-coptidis rhizoma extract (berberine) and to explore the filtration efficiency of bioaerosols. Many studies have demonstrated that berberine has been used as an antiseptic material (Wang, 1998). Therefore this work applied the berberine-pretreated filter as the antiseptic filter. This work applied the fibrous filter coated with the berberine to explore the feasibility of removing bioaerosols. Bioaerosols are generated from a microbial suspension liquid using a Collison Nebulizer. Bioaerosols are mixed with a clean air and then are filtered using fibrous filter pretreated with berberine. To assess collection efficiency of fibrous filter, several factors were investigated, including the microbial species, berberine concentrations, higher and lower relative humidity, and different face velocities. The filtration efficiency of bioaerosols was assessed by sampling, incubation, and counting the numbers of viable colony before and after filtration. In addition, the aerodynamic particle sizer was used to explore different removal mechanisms for bioaerosols. This work will show the results of the feasibility of removal different bioaerosols by berberine coated on fibrous filter. Figure 1 plots the aerosol penetration through the untreated filter and 1.0% berberine-pretreated filters using 1.0-μm PSL aerosols and E. coli bioaerosols at face velocities of 10 cm/s (RH 30%). The experimental results reveal that the aerosol penetrations through the untreated filter and 1.0% berberine pretreated filters at a face velocity of 10 cm/s are approximately 65%, and 64%, respectively. The results also show that penetration of E. coli

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Untreated Fiter Pretreated Filter with Berberine

Untreated Fiter Pretreated Filter with Berberine

Figure 1. Penetration through untreated and berberine pretreated filter with 1.0 μm PSL aerosols and E.coli bioaerosols The authors would like to thank the National Science Council of Republic of China for financially supporting this research under Contract No. NSC. 972622-E-464 -001-CC3. Eduard, W., Sandven, P., & Levy, F. (1993). Am. J. Ind. Med., 24, 207-222 Lance, W. (1996). Journal of Air and Waste Manage. Assoc., 46, 98-126. Melbostad, E., Eduard, W., Skogstad, A., Sandven, P., Lassen, J., Sostrand, P., & Heldal, K. (1994). Am. J. Ind. Med., 25, 59-63. Wnag, B. X. (1998). Chinese herbal medicine pharmacology. Tianjin, China: Tianjin Science and Technology Press.

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