Assessment of Peripheral Neuropathy in Patients

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Oct 21, 2013 - in the form of mononeuritis multiplex, sensorimotor neuropathy, and entrapment neuropathy [5]. Clinical neuropathy may present with a wide ...
Original Article Ann Rehabil Med 2014;38(2):249-255 pISSN: 2234-0645 • eISSN: 2234-0653 http://dx.doi.org/10.5535/arm.2014.38.2.249

Annals of Rehabilitation Medicine

Assessment of Peripheral Neuropathy in Patients With Rheumatoid Arthritis Who Complain of Neurologic Symptoms Mi Kyung Sim, MD1, Dae-Yul Kim, MD, PhD1, Jisun Yoon, MD1, Dae Hwan Park, MD1, Yong-Gil Kim, MD, PhD2 1 Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul; 2Division of Rheumatology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Objective To assess the prevalence of peripheral neuropathy in patients with rheumatoid arthritis (RA) having neuropathic symptoms, and to investigate the relationship between electrophysiological findings of peripheral neuropathy and clinical findings of RA. Methods Patients with a clinical diagnosis of RA and who had tingling or burning sensation in any extremity were electrophysiologically examined for evidence of peripheral neuropathy. Study parameters, including age, gender, laboratory parameters, duration of RA, and medication, were recorded. The symptoms and signs of neuropathy were quantified with the neuropathy symptom score, and the functional statuses of these patients were assessed. Results Out of a total of 30 RA patients, 10 (33%) had peripheral neuropathy: 2 had bilateral carpal tunnel syndrome (CTS), 5 had unilateral CTS, 1 had sensory polyneuropathy, and 2 had motor-sensory polyneuropathy. The mean ages of the patients with and without peripheral neuropathy were 69.4 and 56.5 years, respectively (p50 Ulnar 5.0 >50 Deep peroneal 2.0 >40 Posterior tibial 5.0 >40 F-wave Median