Jun 10, 2014 - Keywords: Acute stroke, Hyaluronic acid, Intracerebral hemorrhage, Ischemic ... bound enzymes called hyaluronan synthases that form D-.
JOURNAL OF NEUROINFLAMMATION
Tang et al. Journal of Neuroinflammation 2014, 11:101 http://www.jneuroinflammation.com/content/11/1/101
RESEARCH
Open Access
Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients Sung-Chun Tang1, Shin-Joe Yeh1, Li-Kai Tsai1, Chaur-Jong Hu2, Li-Ming Lien3, Giia-Sheun Peng4, Wei-Shiung Yang5,6, Hung-Yi Chiou7 and Jiann-Shing Jeng1*
Abstract Background: Activation of hyaluronic acid (HA) and associated enzyme synthesis has been demonstrated in experimental stroke animal models. Our study aimed to investigate the plasma levels of HA in acute stroke patients and the associations between HA levels and functional outcome. Methods: This was a multicenter case–control study. Acute stroke patients and age- and sex-matched non-stroke controls were recruited. Plasma levels of HA in acute stroke patients were determined at
