Design principles for riboswitch function ... design of synthetic riboswitches. Theophylline riboswitch ... This blog page provides a discussion of a paper and a.
Microbial Biotechnology (2011) 4(5), 683–684
doi:10.1111/j.1751-7915.2011.00288.x
Web alert Bacterial riboswitches An annotated selection of World Wide Web sites relevant to the topics in microbial biotechnology
This wikipedia entry provides an extensive description of natural and engineered riboswitches. Most known riboswitches have been found in bacteria.
On and off riboswitches were deployed in tandem to produce regulation that mimics an electronic band-pass filter.
Improved riboswitch for atrazine https://etd.library.emory.edu/view/record/pid/emory:92rgn
Design principles for riboswitch function
This webpage provides a link to an electronic thesis file describing a riboswitch that responds to the herbicide atrazine.
http://www.ploscompbiol.org/article/info%3Adoi%2F10. 1371%2Fjournal.pcbi.1000363 This web article describes modeling for the effective design of synthetic riboswitches.
Synthetic riboswitches in bacteria http://www.asm.org/index.php/news-room/syntheticriboswitches-turn-on-bacterial-genes.html?title= Synthetic+Riboswitches+Turn+On+Bacterial+Genes
The development of synthetic riboswitches requires the ability to screen aptamers for the ability to bind molecules of interest. The use of the method to develop a riboswitch for the natural product theophylline is described.
This blog page provides a discussion of a paper and a good overview of riboswitches.
This page contains a patent on riboswitches. As described, riboswitches can be used to make biosensors, engineer metabolism and carry out gene therapy. Switching off drug resistance http://mag.digitalpc.co.uk/olive/ode/hchembiol/ LandingPage/LandingPage.aspx?href=SENIQm9kZS8y MDEwLzA4LzAx&pageno=Mw..&entity=QXIwMDMwMw.. &view=ZW50aXR5 A ribozyme has been explored to block bacterial resistance to beta-lactam antibiotics.
This description of bacterial riboswitches is from the Microbe blog. Links to additional information are provided.
New functions of riboswitches http://gradworks.umi.com/34/40/3440596.html This page provides a link to a thesis describing novel functions of riboswitches. With widespread genome sequencing, more types of riboswitches are being identified in bacteria.
This Facebook page describes ribozymes that recognize purine nucleotides. There are links to Protein Databank files to these ribozymes. Riboswitch finder http://riboswitch.bioapps.biozentrum.uni-wuerzburg.de/ server.html
This link is to a lecture on riboswitches. Lawrence P. Wackett McKnight Professor BioTechnology Institute Department of Biochemistry Molecular Biology and Biophysics University of Minnesota St Paul, MN 55108, USA
This database allows one to screen sequences for potential function as ribozymes.
