Body Mass Index, Leptin and Leptin Receptor ... - Semantic Scholar

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Berkeley, CA 94720-7360. Phone: (510) 643-5041; Fax: (510) 642-0427. E-mail: [email protected]. Cancer Epidemiology, Biomarkers & Prevention. 779.
Cancer Epidemiology, Biomarkers & Prevention

Body Mass Index, Leptin and Leptin Receptor Polymorphisms, and Non-Hodgkin Lymphoma Christine F. Skibola,1 Elizabeth A. Holly,2 Matthew S. Forrest,1 Alan Hubbard,1 Paige M. Bracci,2 Danica R. Skibola,1 Christine Hegedus,1 and Martyn T. Smith1 1 School of Public Health, University of California, Berkeley, California and 2Department of Epidemiology and Biostatistics, University of California, San Francisco, California

Abstract In a population-based case-control study, obesity was associated with elevated odds ratios (ORs) for non-Hodgkin lymphoma (NHL), and the two major subtypes, diffuse large cell (DLCL) and follicular lymphoma (FL). Those who were obese (body mass index z 30) were up to three times more likely to develop NHL or its major subtypes than persons with body mass index of 20 to