Pappagianis,2. Jim McBaln,'. Sea World of Califor- ... of California,. Davis,. Davis,. California. 95616,. USA; and3. Corresponding author. (e-mail: tom.reidarson.
Juunsal
Coccidioidomycosis Thomas nia, 500
in a Bottlenose
H. Reidarson,13 Lynn Sea World Drive, San
A
(Tursiops
stranded
monary dolphin
initially
dyspnea
that
infection
include
bottlenose
dolphin
of
presented
with
rapidly
served
lymph tissues,
dospores served brain. served A
DNA
mild
worsened
Gen-Probe
48
hr
mitEs.
immitis
performed
sea
and sea reported
lions
(Enhydra
otters case
lutris),
this
tion
port, fungal Tursiops
immitis, pulmonary
a
An
adult in
32#{176}51’N)
on USA). peared weight
female
and
the
ings,
a
tentative
pneumonia Chester, istered
La
Jolla,
and
taken
to
beached
3 June
dolphin rescued from (1 17#{176}15’W/
gilli)
Sea
animal 1995
World
of
quarantine
(San
Diego,
On presentation, very thin, weighed might be expected
Cali-
California,
the dolphin ap167 kg (normal to be 250 kg),
and displayed blood sample
mild inspiratory dyspnea. was drawn, culture swabs
A of
the
and
on
blood nexa,
blowhole
anus
and Sabouraud’s Kansas, USA)
the dolphin was then x 1.2 m deep pool. The dolphin swam normally,
were
for
agar (Remel, microbiology,
placed
initially and after
smeared
into
a 9
X
started
buoyant.
Despite
her
On ber
thickness
an
of
measuring the
with
swimshe
died
(normal miliary
in diameter,
right
caudoventral
lymph
nodes
containing the
compartment
was
body
of the
with
larvae, rubber
were
caseous
there
along
nematode
Representative lected and fixed
3-
diffuse
8 to 9 cm and
addition,
latex
blub-
0.3-10 cm throughout single large firm caseous
perihilar
in
dol-
average
cm
contained
enlarged, ulcer
the
an
0.75-1
left
Both
3 cm
and day,
examination,
nodules,
In
next
evening.
in
and
stabilization signs
the
and
remaining
clinical during
the
swimming
apparent
emaciated
both
of stopped
difficulty
post-mortem was
is spp.
629
bacterial
dolphin
while
have
following
ameter
alert, to eat
find-
of
the
respiratory pattern
phin
ach
clinical
administration
listing
to
by
appeared 3 hr began
after dose,
appeared
terial.
9
1).
hematologic diagnosis
hr
12
regions.
Leand
(Table
respiratory
abnormal
antibiotic
firm
lym-
erythro-
hyperfibrinoge-
iron
severe
4 cm). The lungs nodules, measuring both lobes, and
facility,
shift,
Pennsylvania, USA) was adminorally at 15mg/kg daily. Approxi-
mately
the
left
was made and trimethoprim (Smith Kline Beecham, West
sulfadiazine
first
inflamma-
elevated
serum
the
same
which
moderate
rate,
signs
of
bottlenose was California
truncatus
a beach fornia’s
on
a coun-
the
performed
of
low
Im-
worsened
neutrophilia,
and
ming (Tursiops
were
sedimentation
Based
gilli.
truncatus
629-631 1998
to the right when fibrinogen, and se-
eosinopenia,
nemia,
dolphin, case recoccidioidomycosis, disease, mycosis,
Bottlenose
to list serum
including
in
nearly
dyspnea
evidence
cyte
is the first in a ceta-
strongly
At
chemistries
eating, words: Coccidioides disease,
pp.
Ass(Kiation
Sea World of Califor-
inspiratory
phopenia,
cean. Key
her
rum
californianus)
of coccidioidomycosis
swim
fashion.
provided
infection by C. imfor antibodies to C. and was negative for
(Zalophus
California
and she began resting. A CBC,
to
all known marine morbilliviruses. Although there have been reports of C. immitis infections in free ranging marine wildlife, including California
1998,
I)iseasr
of Medical Microbiology and 95616, USA; and3 Corresponding
and
time
on
34(3),
Diseases, © \Vildjif,’
Jim McBaln,’
Department
terclockwise
inspiratory
over
test
isolate confirmed Serum was positive at a titer of 1: 128
purified
Pappagianis,2
voluntarily
buoyancy abnormalities and finally At necropsy, caseous nodules were obthroughout the lungs and perihilar nodes. On histological examination of double walled organisms containing encharacteristic of C. immitis were obin lung, perihilar lymph nodes, and Pyogranulomatous infiltrates were obin the lung and perihilar lymph nodes
death.
only.
Demosthenes
gilli) succumbed to a pulCoccidioides immitis. The
truncatus
%%ildlife
Dolphin
Diego, California 92109, USA; 2 University of California, Davis, Davis, © anheuser-busch.com)
munology, School of Medicine. author (e-mail: tom.reidarson
ABSTRACT:
A. Griner,1
of
a
ma-
7 cm first
a few
Anisak-
and
four,
kelp,
di-
stom-
strips.
tissue samples in 10% neutral
were colbuffered
5
630
JOURNAL
TABLE
1.
tninc’atus
OF WILDLIFE
Selected gilli ) with
DISEASES,
hematological
VOL.
and
34, NO. 3, JULY
biochemical
1998
values
frouii
a free-ranging
bottlenose
(Tur8iops
(lolpliiui
coccidioidomvcosis.
Normal’
White
1)100(1
Band
cells
X103/p.l
( 1 , 00) 0
7,216
4,288
(408)
1,152
(320)
Lymphocytes
X103/p.l
492
Monocytes
X10:l/p.l
164
128
Eosinophils
X1&3/p.l
82
768
Ers’throc’te
Sediuiientation
mn
Rate
in
(320) 01)
