Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam. INTRODUCTION To minimize secondary lung damage during ...
Correlation between lung volume changes measured by electrical impedance tomography and respiratory inductance plethysmography in high-frequency ventilated preterm infants P.S. van der Burg, M. Miedema, F.H.C. de Jongh, A.H.L.C. van Kaam Department of Neonatology, Emma Children’s Hospital, Academic Medical Center, Amsterdam
INTRODUCTION To minimize secondary lung damage during mechanical ventilation, it is essential to optimize lung volume. Electrical impedance tomography (EIT) and respiratory inductive plethysmography (RIP) are non-invasive tools that measure, respectively, regional and global changes in lung volume. The correlation between these techniques, however, has never been assessed. METHODS
Lung volume changes during a stepwise individualized oxygenation-guided recruitment manoeuvre were monitored with EIT and RIP in preterm high-frequency ventilated infants with respiratory distress syndrome. Using the pressure/impedance and pressure/ inductance pairs, the inflation and deflation limbs were reconstructed according to Venegas and characterized by calculating the inflection points. In addition, oscillatory tidal volume changes were assessed at each pressure step using both EIT and RIP. Analysis was performed using Pearson’s correlation coefficient (r).
RESULTS
Fifteen preterm infants with a mean gestational age of 28.0 ± 2.6 weeks and a birth weight of 1027 ± 514 grams were included. End-expiratory lung volume changes measured by EIT and RIP were significantly correlated for twelve patients (mean r: 0.94 ± 0.05). The upper inflection point on the inflation (r: 0.91, p
