Hindawi Publishing Corporation Journal of Oncology Volume 2015, Article ID 486850, 2 pages http://dx.doi.org/10.1155/2015/486850
Corrigendum Corrigendum to ‘‘Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest’’ Suwit Duangmano,1,2 Phorntip Sae-lim,3 Apichart Suksamrarn,3 Pimpicha Patmasiriwat,1 and Frederick E. Domann2 1
Faculty of Medical Technology, Mahidol University, Bangkok, Thailand Free Radical and Radiation Biology Program, Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, USA 3 Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand 2
Correspondence should be addressed to Frederick E. Domann;
[email protected] Received 4 June 2014; Accepted 24 July 2014 Copyright © 2015 Suwit Duangmano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In Figure 3(a) of the published paper entitled “Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest,” we mistakenly used the same flow cytometry data panel for the MDA-MB231 cells treated with 2.5 𝜇M and 5 𝜇M cucurbitacin B. The corrected figure and legend are presented here.
2
Journal of Oncology Control 3.93
105
2.45
30.6
103
94.4
1.24
0 10
2
10
3
10
4
10
5
52.2 0 10
1.55
105
97.4 10
3
10
8.96
4
10
5
24.6
58.7 0 102
7.51
105
104
7.82 10
3
10
4
10
0 10
2.33 10
10
57.8 0 10
12.1 2
4
10
5
10
3
10
4
105
FITC-A
2.53
15.9
6.57
105
14.2
104 PI-A
PI-A 88.8 3
27.3
MDA-MB-231
5
103 102 0
105
103 102 0
104
103
10
4
2.73
105
FITC-A
1.4
10
3
104
FITC-A
2
2
FITC-A
103 102 0
0.59 2
21.6
0 10
PI-A
PI-A
PI-A
103
0 10
PI-A
10
46
5
104
104
102 0
10
4
MCF7:5C
FITC-A
105 0.46
105
10
3
103 102 0
14.8 2
FITC-A
102 0
31.4
104
103 102 0
0.92
105
104 PI-A
PI-A
104
102 0
5 𝜇M
2.5 𝜇M
0.45
PI-A
105
70.1 0 102
FITC-A
11.5 103
104
SKBR-3
103 102 0
68.1
105
0 102
FITC-A
11.1 103
104
105
FITC-A
(a)
60
∗∗
Apoptosis (%)
50
∗∗ ∗
40
∗
30
∗
∗
20 10 0 Control
2.5 𝜇M
5 𝜇M
Concentration (𝜇M)
MCF7:5C MDA-MB-231
SKBR-3 (b)
Figure 3: Cell death of breast cancer cells induced by cucurbitacin B. (a) MCF7:5C, MDA-MB-231, and SKBR-3 were incubated with the indicated doses of cucurbitacin B for 48 hr and apoptosis was analyzed by staining phosphatidylserine translocation with FITC-Annexin V. Annexin V staining is represented on the 𝑥-axis and PI staining is represented on the 𝑦-axis. The most representative result of three independent experiments is shown. 5 𝜇M data for MDA-MB-231 are not shown. Simple vertical bars represent the mean apoptosis rate of all of breast cancer cells (b). Results shown are the average of three independent experiments. ∗ 𝑃 < 0.05 versus nontreated control; ∗∗ 𝑃 < 0.01 versus nontreated control.
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