CURRICULUM VITAE

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Progenitor Cells.” N.L. Boyd, K.R. Robbins, S.K. Dhara, F.D. West, S.L. Stice. ... Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment and  ...
CURRICULUM VITAE Franklin D. West Assistant Professor Edgar L. Rhodes Center for ADS University of Georgia Athens, GA 30602-2771 Phone: (706) 542-0988 Fax: (706) 542-0399 Email: [email protected]

RESEARCH INTERESTS My research interests are in the field of stem cell biology and regenerative medicine with an emphasis in directed differentiation of human embryonic stem cells into germ cells.

EDUCATION Sept 2004-Dec 2008 University of Georgia, Doctor of Philosophy in Animal and Dairy Science. Dr. Steven L. Stice (Advisor) Sept 2000-Dec 2003 Morehouse College, Bachelors of Science in Biology, Magna Cum Laude, GPA 3.74 Sept 1996-May 2000 A. R. Johnson Health Science and Engineering Magnet High School, College Preparatory and Vocational Seals, Honors

Academic and Professional Positions Jul 2010 - Current

Assistant Professor

University of Georgia

Jan 2009 - Jun 2010

Assistant Research Scientist

University of Georgia

Nov 2007 - Dec 2008

Independent Contractor

Aruna Biomedical Inc.

REFEREED PUBLICATIONS 1. “Identification of Unique Cell Surface Markers for Human Embryonic Stem Cell Lines and Derivatives Using High-throughput Proteomic Analysis.” Brian A. Gerwe, Peggi Angel, Franklin D. West, Kowser Hasneen, Ron Orlando and Steve Stice. Journal of Proteomics. In Review. Feb 2011. 2. “Human Haploid Cells Differentiated from Meiotic Competent Clonal Germ Cell Lines that Orginated from Embryonic Stem Cells.” F. D. West, J. L. Mumaw, A. Gallegos-Cardenas, A. Young and S. L. Stice. Stem Cells and Development. [Epub ahead of print 2010 Oct 7]. 3. "Glial Cell-line Derived Neurotrophic Factor Enhances in vitro Differentiation of Mid/hindbrain Neural Progenitor Cells to Dopaminergic-like Neurons." A. Young, K. Assey, C. Sturkie, F. D. West, D. Machacek, S. Stice. Journal of Neuroscience Research. 2010 Nov 15;88 (15): 3222-32. 4. “Porcine Induced Pluripotent Stem Cells Produce Chimeric Offspring.” F. D. West, S. L. Terlouw, D. Kwon, J. L. Mumaw, S. K. Dhara, K. Hasneen, J. R. Dobrinsky and S. L. Stice. Stem Cells and Development. 2010 Aug 19 (8): 1211-20 [Epub ahead of print 2010 Apr 9]. 5. “Lineage-Specific Promoter DNA Methylation Patterns Segregate Adult Progenitor Cell Types.” A. L. Sorensen, S. Timoskainen, F. D. West, K. Vekterude, A. C. Boquest, L. Ahrlund-Richter, S. L. Stice and P. Collas. Stem Cells and Development. 2010 Aug 19 (8): 1257-66 [Epub ahead of print 2009 Nov

3]. 6. “KIT ligand and bone morphogenetic protein signaling enhances human embryonic stem cell to germlike cell differentiation.” F. D. West, M. I. Roche-Rios, S. Abraham, R. R. Rao, M. S. Natrajan, Bacanamwo, M and S. L. Stice. Human Reproduction. 2010 Jan 25 (1): 168-78 [Epub ahead of print 2009 Oct 19]. 7. “Human Embryonic Stem Cell Derived Mesoderm-like Epithelium Transitions to Mesenchymal Progenitor Cells.” N.L. Boyd, K.R. Robbins, S.K. Dhara, F.D. West, S.L. Stice. Tissue Engineering. 2009 Aug 15 (8): 1897-907. 8. “Enrichment and Differentiation of Human Germ-like Cells Mediated by Feeder Cells and Basic Fibroblast Growth Factor Signaling.” Franklin D. West, David W. Machacek, Nolan L. Boyd, Kurinji Pandiyan, Kelly R. Robbins, and Steven L. Stice. Stem Cells. 2008 Nov 26 (11): 2768-76 [Epub ahead of print 2008 Aug 21]. 9. “BMP4 Promotes Formation of Primitive Vascular Networks in Human Embryonic Stem Cell Derived Embryoid Bodies.” N.L. Boyd, S.K. Dhara, R. Rekaya, E.A. Godbey, K. Hasneen, R.R. Rao, F.D. West III, B.A. Gerwe, S.L. Stice. Experimental Biology and Medicine. 2007 Jun 232:833-43. 10. “Uniform adherent neural progenitor populations from rhesus embryonic stem cells.” Deanne Tibbitts, Raj R. Rao, Soojung Shin, Franklin D. West and Steven L. Stice. Stem Cells and Development. 2006 Apr. 15: 200-208.

NON-REFEREED PUBLICATIONS (Semi-Technical/Lay Publications) 1. F. D. West and S. L. Stice. Understanding the Biology and Underlying Mechanisms of Gamete Development, Fertilization and Embryogenisis. Refine Methods for Production of Genetically Modified Animals to Improve Livestock Productivity Efficiency. Germ Cell and Embryo Development and Manipulation for the Improvement of Livestock. W-1171 Multistate Research Committee Technical Report. 2009 Jan. Pg. 26-27.

FUNDING 1. Bill and Melinda Gates Foundation. Reducing Disease in Livestock August 2010-Current , Support: $150,000 ABSTRACTS 1. Henderson, W. Mathew, West, Franklin D., Anderson, Benjamin M., Smith, Mary Alice, Stice, Steven L. Metabolomic Profiling of Human Embryonic Stem Cell Derived Germ-like Cells Following Exposure to Steroid Hormones. The Teratology Society; 2010 Jun: Louisville, (KY). 2. Franklin West, M.S. Natrajan, M.I. Roche-Rios and S.L. Stice. Bone Morphogenetic Protein and KIT Ligand Signaling Enhances Human Embryonic Stem Cell Differentiation into Early Male Germ Cells. Society for the Study of Reproduction; 2009 Sept: Pittsburgh, (PA). 3. A. Young, C. D. Sturkie, F. D. West, D. W. Machacek and S. L. Stice. Differentiation of Human Embryonic Stem Cell Derived Neural Progenitors Towards a Dopaminergic Phenotype. Neuroscience; 2008 November: Washington D. C. 2. F.D. West, M.S. Natrajan, M.I. Roche-Rios, M.A. Bedell and S.L. Stice. Bone Morphogenetic Protein and KIT Ligand Signaling Enhance Human Embryonic Stem Cell Differentiation into Early Sperm Cells. Georgia Life Sciences Summit; 2008 Sept: Atlanta, (GA). 3. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment and Differentiation of Germ-Like Cells from Human Embryonic Stem Cells. Georgia Stem Cell Initiative; 2008 May: Athens, (GA). Recipient of 3rd place in poster competition. 4. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment of Germ-Like Cells in Human Embryonic Stem Cells Cultures. GTECH Industry Partners Symposium; 2007 Oct: Atlanta, (GA). 2

5. F.D. West, K. Pandiyan, K. Robbins and S. L. Stice. Human Embryonic Stem Cells Differentiate into Sperm and Eggs Precursor Cells. Georgia Life Sciences Summit; 2007 Oct: Atlanta, (GA). 6. Franklin West, Kurinji Pandiyan, Kelly Robbins and Steve Stice. Enrichment of Germ-Like Cells in Human Embryonic Stem Cell Cultures. Society for the Study of Reproduction 40th Annual Meeting; 2007 Jul 21-25: San Antonio, (TX). 7. Simon, C.M., Schumm, M.A., Sturkie, C.D., West, F.D., Stice, S.L., and LaPlaca, M.C. A Tissue Engineering Approach for Transplanting Human Neuroepithelial Progenitors into the Contused Spinal Cord. Engineering Tissues; 2007 March; Hilton Head, (SC). 8. J. Mumaw, D. Machacek, M. Mitalipova, J. Shields, M. Galeano, M. Pecoraro, C. Sturkie, F. West, and S. L. Stice. Scanning Electron Microscopy on Human Embryonic Stem Cells: Differentiation to Neural Progenitors to Neurons. The University of Georgia Biomedical and Health Science Institute 2006 Annual Retreat; 2006 Sept 22; Athens (GA). 9. West F., Pandiyan K., Robbins K. R., and Stice S. L. 2006. Differentiation of Primordial Germ Like Cells from Human Embryonic Stem Cells [Abstract]. The University of Georgia Biomedical and Health Science Institute 2006 Annual Retreat; 2006 Sept 22; Athens (GA). 10. Simon, C. M., Schumm, M. A., Sturkie, C. D., West, F.D., Stice, S. L., and LaPlaca, M. C. Tissue Engineered Constructs for Neuroepithelial Progenitor Transplanted to the Contused Rat Spinal Cord. 8th International Neurotrauma Symposium. 2006 May; Rotterdam, Netherlands. 11. CM Simon, MA Schumm, CD Sturkie, FD West, SL Stice, MC LaPaca. 2006. Transplantation of human neuroepithelial progenitor cells into the injured rat spinal cord: a tissue engineering approach. GTEC National Science Foundation site visit; 2006 Apr 17-19: Atlanta, (GA). 12. Michael A. Schumm, Crystal M. Simon, Carla D. Sturkie, Franklin D.West, Steve L. Stice, and Michelle C. LaPlaca. 2005. Human Embryonic Stem Cell Transplants to the Contused Spinal Cord. GTEC Educational Partners Symposium; 2005 Nov 8-10: Atlanta (GA). 13. Franklin D. West. The Effects of Male Population Density on Mate Choice and Offspring Production in Milkweed bugs, Onocopeltus fascoatus. Proceedings of the National Conference on Undergraduate Research. 1st ed. CD-ROM. 2002: Asheville (NC).

SERVICE TO PROFESSIONAL JOURNALS Adhoc Reviewer for the Following Journals Stem Cells and Development-2010 Molecular Reproduction and Development- 2010 Tissue Engineering- 2010 Journal of Visualized Experiments- 2009 Journal of Proteome Research- 2009

EXPERIENCE 2010 2004- 2009

2007- 2008 2004-2008

2002-2003

University of Georgia Induced Pluripotent Stem Cell Workshop  Director and Instructor National Institutes of Health Human Embryonic Stem Cell Toolbox (HEST) Workshop  Instructor (2007-2009)  Support Staff (2004-2006) Aruna Biomedical Inc.  Product Production and Quality Control Support, Independent Contractor Graduate Recruitment Opportunities Research Assistantship  Derivation and Differentiation of Germ Cells from Human Embryonic Stem Cells. Dr. Steven L. Stice (Advisor), University of Georgia Georgia Power Fellowship  Host Competition Between the Jewel Wasp, Nasonia vitripennis, and the WOW bug, Melittobia digitata. 3

2002

2002

2001-2002

2001

2000-2001

1997-2000 1996-2000

Research Experience for Undergraduates (REU) Fellowship  The Effects of Wet/Dry Season, Drought, and Hierarchy on Stress Levels in Male Yellow Baboons, Papio cynocephalus. Dr. Jeanne Altmann (Advisor), Princeton University, Amboseli, Kenya Princeton Summer Research Experience (PSRE) Fellowship  The Effects of Wet/Dry Season, Drought, and Hierarchy on Stress Levels in Male Yellow Baboons, Papio cynocephalus. Dr. Jeanne Altmann (Advisor), Princeton University. Georgia Power Fellowship  The Effects of Male Population Density on Mate Choice and Offspring Success in Milkweed Bugs, Onocopeltus fascoatus. Dr. Lawrence Blumer (Advisor), Morehouse College. Cornell University/Leadership Alliance Research Fellow  The Relationship Between the Predatory Whelk, Nucella lapillus, and its Prey, the Blue Mussel, Mytilus edulis. Dr. Jan Factor (Advisor), Cornell University, Shoals Marine Laboratory. Georgia Power Fellowship  Mate Choice in Bean Beetles. Dr. Lawrence Blumer (Advisor), Morehouse College. Veterinary Assistant  South Pointe Animal Hospital, Janet Distler, D.V.M. Veterinary Assistant  Springwood Veterinary Clinic, Bruce Gradous, D.V.M.

TEACHING EXPERIENCE 2006-2008

2007 2006-2007 2006 2006 2005 2005 2001-2002

Center for Undergraduate Research Opportunities (CURO) Research Fellowship  Mentor of Ms. Muktha Natrajan  Mentor of Ms. Kurinji Pandiyan Animal Biotechnology Course Teaching Assistant Introduction to Animal and Dairy Science Laboratory Teaching Assistant Young Scholars Program  Mentor of Mr. Amadu Ndiaye Companion Animal Care Course Teaching Assistant Cloning and Stem Cells Course Teaching Assistant Horse Operant Conditioning and Training Course Teaching Assistant General Biology Course Teaching Assistant

PROFESSIONAL AFFILIATIONS AND HONORS 2006-Present 2002-Present 2001-Present 2010 2004-2008 2008 2006 2005

Gamma Sigma Delta: The Honor Society of Agriculture Golden Key International Honour Society, Member National Society of Collegiate Scholars, Member Georgia Trends Top 40 Under 40: Georgia’s Best and Brightest Animal and Dairy Science Graduate Student Association  President 2005-2006 Georgia Tech Student Travel Award (Meeting: Regenerative Medicine: Advancing to Next Generation Therapies) Out Standing Teaching Assistant Award for the College of Agricultural and Environmental Sciences, Recipient University of Georgia Graduate Student Travel Grant (Meeting: Therapeutic Potential of Stem Cells in Reproductive Medicine) 4

2002-2003 2002-2003 2002-2003 2002-2003 2003 2002-2003 2001-2003 2000-2003 2000-2003

2000-2003 2000-2003 2000-2003

Achievement Rewards for College Scientists (ARCS) Scholarship Recipient Minority Access to Research Careers Undergraduate Student Training in Academic Research (MARC U*STAR) Scholarship Recipient; National Institute of Health Beta Kappa Chi Scientific Honor Society, Member Associate College of the South Environmental Intern  Director of Solar Cell Project Dr. and Mrs. Francis Davis Scholarship Recipient Who’s Who Among College Students Leadership Alliance, Member David and Lucille Packard Scholarship Recipient Samuel M. Nabrit Research Society  Vice-President 2002-2003  Treasurer 2001-2002  Vice-President of Freshmen 2000-2001 Hope Scholarship Recipient Morehouse Tuition Scholarship Recipient Georgia Equalizer Grant Recipient

SELECTED INVITED PRESENTATIONS 2011, “Derivation of Induced Pluripotent Stem Cells from Domestic Livestock Species. Clemson University. February. Clemson, SC. 2011, “Stem Cell Derived Germ Cells: A model for human germ cell development.” Morehouse College. February. Atlanta, GA. 2011, “Stem Cell Derived Germ Cells: Improving the way we live, eat and the world around us.” ARCS Foundation. January. Atlanta, GA. 2010, “Opportunities and Challenges of Generating Stem Cell Derived Germ Cells.” National Science Foundation Integrated Graduate Education and Research Training Grant (IGERT) program. Georgia Institute of Technology. November. Atlanta, GA. 2008, “Enrichment and Differentiation of Human Embryonic Stem Cells into Male Germ-Like Cells.” National Institute of Health Human Embryonic Stem Cell Toolbox (HEST) Workshop. Richmond, VA. 2008, “Stem Cells and Cloning: Great Potential and Challenges.” University of Georgia STARS (Student and Teacher Applying Real-Life Science) Program. Athens, GA. 2007, “The Science of Stem Cells and Cloning.” Athens Area Chamber of Commerce. Athens, GA. 2007, “Cloning and the Social and Economic Implications.” Kiwanis Club. Commerce, GA. 2005, “Cloning: Science and Function.” Teachers Training Teachers. Athens, GA

Technical Skills Human, Primate and Mouse Embryonic Stem Cell Culture Adult Stem Cell, Induced Pluripotent Stem Cell and General Cell Culture Immunocytochemistry Flow Cytometry and Florescence Activated Cell Sorting (FACS) Quantitative and Qualitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) Western Blotting Mouse and Embryo Dissection Transfection and TransductionDisk Spinning Unit Microscopy Open Water Diving, Certified 5