CV

CURRICULUM VITAE

Abbas Ghaderi Professor of Immunology OFFICE ADDRESS: AA GHADERI Department of Immunology Shiraz Institute for Cancer Research Shiraz University of Medical Science Shiraz Iran PO.Box ٧١٣٤٥-١٧٩٨ FAX Direct: (٠٠)٩٨-٧١١-٢٣٣ ٤٥٨٩ TEL:٠٠٩٨-٧١١ ٢٣٠٣٦٨٧ E-mail: [email protected] Home: Tel: +٩٨-٧١١-٦٢٧٨٤٩٢ PERSONAL First name: Abbas Middle name: Ali Family name: Ghaderi Date of Birth: ٢٣٫٣٫١٩٥٩ Nationality: Iranian Marital status: married QUALIFICATIONS: ١-M.Sc. Immunology ١٩٨٧ Medical School, Birmingham University, Birmingham, UK ٢-Ph.D. Immunology ١٩٩٠ Medical school, Birmingham University, Birmingham, UK UNIVERSITY APPOINTMENT: Assistant professor of Immunology ١٩٩٠-١٩٩٣. Associate professor of Immunology ١٩٩٣-٢٠٠٠. Professor of Immunology: ٢٠٠٠-present

HOSPITAL APPOINTMENT Director of Clinical Immunology laboratory Nemazi Medical Center, Shiraz University of Medical Sciences SPECIAL TRAINING AND AWARDS: ١- WHO fellowship for Vaccinology and biotechnology Lauzan, Switzerlands, ١٩٩٣ ٢- Sanduz short Training award. Application of PCR for HLA-typing, West Midland Blood transfusion center, Birmingham, UK ١٩٩٥ ٣- PCR direct-sequencing applied to molecular genetics of Cancer. Kurume University School of Medicine. Kurume, Japan. ١٩٩٧-١٩٩٨ ٤- WHO fellowship for Vaccinology and biotechnology Puna, India ١٩٩٩ ٥-UICC and Norwegian cancer society joint fellowship for attendance of ١٧th Int. Cancer Congress (Oslo July٢٠٠٢) MEMBERSHIP: ١-British Society for Immunology (BSI) ٢-British Association for Cancer Research (BACR) ٣-Executive committee of Iranian Society for Immunology ADMINISTRATION: ١. Head of Department of Microbiology and Immunology. (١٩٩١-١٩٩٥). Shiraz University of Medical sciences, Shiraz Iran. ٢-Director of Shiraz Institute for Cancer Research (http://icr.sums.ac.ir) ٣. Congress Secretary: The Eight Int. Congress of Geographic Medicine and the ٣rd Iranian Congress of Immunology and Allergy, May ٦-٩ ١٩٩٥, Shiraz-Iran ٤. Congress Secretary: The Ninth Int. Congress of Geographic Medicine (ONCOLOGY) May ١٢- ١٥, ١٩٩٦, Shiraz-Iran ٥- Chairman University Graduate board (٢٠٠٠-٢٠٠١) ٦-Editor-in-Chief: Iranian Journal Immunology (http://iji.sums.ac.ir)

TEACHING EXPERIENCES: a) Immunology to Medical students b) Advanced Immunology to postgraduate students (M.Sc. and Ph.D.) Technical EXPERIENCES: Cellular and molecular Immunology including: Monoclonal antibodies production, Tissue culture, Protein purification and assays by different protein chemistry methods.

Molecular biology techniques including: southern blotting and PCR, sequencing. Updated in designing ELISA based assay for the screening of viral, bacterial and tumor markers.

Collaboration: Division of Oncology, University Surrey England UCLA immunogenetics Unit

Graduate Activity: Ten PhD and over ٢٥ M.Sc. students performed their projects under my supervision.

PUBLICATIONS ١. Ghaderi, A.A., Richardson, P., et. al. (١٩٨٧) Stimulation of B chronic lymphocytic leukemia populations by recombinant interleukin ٤ and other defined growth promoting agents. Leukemia, ٢:١٦٥ ١٧٠. ٢. Stanworth, D.R. and Ghaderi, A.A. (١٩٩٠) The role of high and low affinity IgE receptors in cell signaling processes. Molecular Immunology, ٢٧:١٢٩١ ١٢٩٥ ٣. Ghaderi, A.A., Jones, V.M., Stanworth, D.R. (١٩٩١) Affinity purified soluble Fc RII/CD٢٣ derived from RPMI ٨٨٦٦ cells induces histamine release from human nasal polyp mast cells through a non IgE mediated mechanism. Immunology letter, ٢٧:١١٣ ١١٨. ٤. Ghaderi, A.A. and Stanworth, D.R. (١٩٩١) Affinity purified soluble Fc RII/CD٢٣ induced a monophasic fever in rabbit. Immunology, ٧٣:٥١٠ ٥١١. ٥. Ghaderi, A.A. and D.R. Stanworth (١٩٩٣) Epitope mapping site(s) of binding of Fc RII/CD٢٣ within human IgE. Molecular Immunology, ٣٠:١٦٥٥-١٦٦٣. ٦. Ghaderi, A.A. and D.R. Stanworth. (١٩٩٣) Production and characterization of two murine monoclonal antibodies directed against epitopes exclusive to soluble fragments of Fc RII/CD٢٣. Eur. J. Immunol., ٢٣:٢٩٠٩-٢٩١٥. ٧. Ghaderi, A.A. G. Gaudernack., D.R. Stanworth. (١٩٩٤) Cross linking of a sequential epitope of HLA DR/DP molecules suppressing B lymphocytes growth and inducing homotypic cell aggregation. Immunology Letter, ٣٩:١١٣-١١٩. ٨. Ghaderi, A.A. and Z.Amirghofran. (١٩٩٣) The production of murine monoclonal antibodies directed against human T cell subsets. Med J of Is Rep Iran ٦ :٢٩١-٢٩٥. ٩. Flores Romo, L., Johnson, G.D., Ghaderi, A.A., et al. (١٩٩٠) Functional implication for the topographical relationship between class II and the low affinity IgE receptor:occupancy of CD٢٣ prevents B lymphocytes from stimulating allogenic mixed lymphocytes uresponses. Eur.J. Immunol, ٢٠:٢٤٦٣ ٢٤٦٩. ١٠. Gordon, J., Flores Romo,L., Cairns,J., Pound,J., Stanworth,DR, and Ghaderi,A.A. (١٩٩٠) Multifunctional role of CD٢٣ in the immune response. In "Cytokines:Basic Principles and Clinical application" (eds:S Romagnani and A K Abbas) Raven Press ٦٨:٢٣٩-٢٥٧. ١١. Gordon, J., Flores Romo, L.,Cairns, J., Veronesi, A., Stanworth, DR and Ghaderi, A.A. . Role of CD٢٣ in IgE regulation and beyond. In:"Advances in Prostaglandin, Thromboxan and Leukotrine Research (eds B Sameulsson et al) Raven Press Limited, New York ٢١:٩٨٣٩٨٨،١٩٩٠. ١٢. Amirghofran, Z and Ghaderi, A.A. (١٩٩٣). Determination of a ٤٥ KDa leukocyte common antigen and its unique expression on B cells developments. Iran. J. Med. Sci, ١٧:١٠٩ ١١٥.

١٣. Ghaderi, A.A., Amirghofran, Z. Tabei, SZ (١٩٩٤). CD٣٨ a multilineage glycoprotein and its unique expression on plasma cells. Med J of Is Rep Iran, ٨:١٠٩-١١٣. ١٤. Ghaderi, A.A and Amirghofran, Z (١٩٩٣) CD٥ molecules on B cells is no longer considered as an aberration of expression. Iran J. Med. Sci, ١٨:١٥٩-١٦٥. ١٥.Ghaderi, A.A,. Ghanaat, A., Hakim, SM. (١٩٩٤) Comparison of IgM rheumatoid factors (RF) in patients with Kala-azar, Tuberculosis, Toxoplasmosis and Brucellosis by an EnzymeLinked Immunosorbent assay (ELISA). Iran J. Med. Sci Vol:١٩،١٢٥-١٢٩. ١٦. Ghaderi, A.A,. Yazdanbod, H. (١٩٩٤) Detection of Mycobacterium tuberculosis soluble antigens in cerebrospinal fluids of (CSF) of patients with tuberculous meningitis by a capture ELISA method. Iran J Med Sci, Vol.٢٣:٤١-٤٥. ١٧. Amirghofran, Z and Ghaderi, A.A. (١٩٩٥) Identification of two different intracellular antigens of human leukocyte antigen by monoclonal antibody. Iran J. Med. Sci, ٢٠:٤٨-٥١. ١٨. Ghaderi, A.A., Habibagahi, M., Amirghfran, Z.,Ardehali, S. (١٩٩٥) Determination of a shared epitope between cells from acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL). Med J Islamic Rep Iran, ٩:٢٥٣-٢٥٥. ١٩. Amirghfran, Z., Ghaderi, A.A. (١٩٩٥) Characterization of a murine monoclonal antibody reactive with a leukocyte common antigen and its application for bone marrow transplantation. Transplantation Proceeding, ٢٧:٢٦٥٧-٢٦٥٨. ٢٠. Ghaderi, A.A., Doroudchi, M., Emad, M., R. Amin. (١٩٩٦) Elevation of CD٢١ and CD٢٣ positive peripheral blood mononuclear cells in children with atopic dermatitis. Eur J Dermatol, ٦:٤٢١-٢. ٢١. Ghaderi, A.A., (١٩٩٦) IgE and its Receptors, A Review. Med J of IRI, ١٠:٨٩-٩٧. ٢٢. Ghaderi, AA., Habib-Agahi, M (١٩٩٦) High frequency of Anti-HCV and HTLV.I antibodies in thalassemia major patients of southern Iran. Iran.J.Med.Sci, ٢١:٦٠-٦٢. ٢٣. Farjadian Sh, Kaviani MJ, Ghaderi AA. (١٩٩٦) Molecular Analysis of Pseudomonas aeroginosa strains isolated from hospitalized patients in Shiraz. Iran J. Med. Sci, ٢١:١١٢-١١٨. ٢٤. Saberi-Firozi M, Kafashian F, Hayati E, Ghaderi, A.A. et al. (١٩٩٨). Prevalence of Hydatosis in nomadic tribes of southern Iran. Med J IRI. vol:١٢،١١٣-١١٨. ٢٥. Amirghofran Z, and Ghaderi A. (١٩٩٧). CD٥٣ monoclonal antibody induces expression of CD٣٥ on surface of U٩٣٧ cell line. Turkish J Hematology, ١٤:٩٣-٩٦. ٢٦. Amirzargar A, Mytilineos J, Yousefipour A, Farjadian Sh, Schere S, Ghaderi A.A., Opelz G. (١٩٩٨) HLA-Class II (DRB١, DQA١ & DQB١) associated genetic susceptibility in iranian multiple sclerosis (MS) patients. Eur J Immunogenetics, ٢٥:٢٩٧-٣٠١. ٢٧. Yousefi-Pour GA, Shoshtari-pour JA, Hodjati H, Ghaderi A. (١٩٩٧) Association of HLA class I antigen with Myasthenia Gravis (MG) in southern Iran. Iran J.Med Sci, ٢٢:١٤٩-١٥٠.

٢٨. Amirghofran Z, and Ghaderi A.A. (١٩٩٥) Cross-linking of CD٣٨ molecules induced exprssion of IL-٢ receptor and HLA-DR on human thymocytes. Roum. Arch Microbiol Immunol, ٥٤:٢٦٥-٢٧٠. ٢٩. Amin R, Malekhosseini Z, Ghaderi A. (١٩٩٨) Detection of IgM and IgA rheumatoid factors (IgM,IgA-RFs) in children with active juvenile rheumatoid arthritis (JRA) using ELISA assay. Iran J Med Sci, ٢٣:٦١-٦٣. ٣٠. Gharesi-fard B, Vasaee M, Talaei A, Modjtahedi H, Dean C, Ghaderi A.(٢٠٠٠) Immunohistochemical investigation of breast cancer for the expression of two members of the epidermal growth factor receptor (EGRF) family, c-erBb-١, and c-erBb-٢, and their significance for prognosis. Iran J Med Sci ٢٥:٣١-٣٥ ٣١. Ayatollahi M, Malekhossini Z, Mortazavi H, Jefferis R, and Ghaderi A. (١٩٩٩) Development of an ELISA based method for the detection of pemphigus autoantibodies. Iran Biomedical J.٣::٩٩-١٠١ ٣٢. Modjtahedi H, Saalabian MJ, Ghaderi A, Dean C. Monoclonal anitibody-based therapy of human cancer. (١٩٩٨) Iran J Med Sci, ٢٣:١٢٦-١٣١. ٣٣. Ghaderi A, Shoshtari-Pour JA, Farjadian Sh, Yousefi-Pour Gh, Amirzargar A. (٢٠٠٠) HLA-DRB١ allele frequencies in Myasthenia Gravis (MG) patients from southern Iranian population. Med J Isl Rep Ir,١٤ ٢٢٣-٢٢٥. ٣٤. Kamali Sarvestani E, Khezri A, Vessal M, Ghaderi A. (١٩٩٩) A simplified and reproducible two-step method for the purification of prostate-specific antigen. Iranian Biomedical Journal ٣:٨٧-٩١. ٣٥. Doroudchi M, Kremer K, Basiri E, Kadivar MR, van Soolingen D, Ghaderi A. IS٦١١٠RFLP and Spoligotyping of Mycobacterium tuberculosis isolates in Iran. Scand J Infect Dis, ٢٠٠٠; ٣٢(٦):٦٦٣-٨. ٣٦. Doroudchi M, Samsami A, Emad K, Ghaderi A. Seroepidemiological survey of rubella immunity among three different populations in Shiraz-Iran. Eastern Mediterranean Health Journal. ٢٠٠١; ٧(١/٢): ١٢٨-١٣٨. ٣٧. Amirzargar A, Mostafavi A, Farjadian Sh, Ghaderi A. Susceptibility of HLA-class II alleles in Iranian type I diabetic patients. Iran J Med Sci. ٢٠٠٠, ٢٥:١٠٩-١١٣ ٣٨. Ghaderi A, Talei A, Farjadian Sh, Mossalae A, Doroudchi M, and Kimura H. Germline BRCA١ mutations in Iranian women with breast cancer: Cancer Letter, ٢٠٠١،١٦٥:٨٧-٩٤. ٣٩. Ghaderi A, Talei A, Gharesi fard B, Farjadian Sh, Amirzargar A, Vasei M. HLA-DRB١ alleles and the susceptibility of Iranian patients with breast cancer. Pathology Oncology Research,٢٠٠١;٧(١):٣٩-٤١.

٤٠. Amirzargar, A., Mytilineos, J., Farjadian, Sh. , Doroudchi, M., Scherer, S., Opelz, G., and Ghaderi, A.A. HLA Class?II allele frequencies and haplotype association in Iranian normal population: Human Immunoogy ٢٠٠١, ٦٢:١٢٣٤-١٢٣٨. ٤١. AM Pezeshki, S Farjadian, A Talei, M Vasei, B Gharesi-fard, M Doroudchi, A Ghaderi. P٥٣ gene alteration and protein expression in Iranian women with infiltrative ductal breast carcinoma. Cancer Letter ٢٠٠١, ١٦١:٦٩-٧٥. ٤٢. Yoshiro Koda, Hidenori Tachida, Hao Pang, Yuhua Liu, Mikiko Soejima, Abbas A. Ghaderi, Osamu Takenaka and Hiroshi Kimura. Contrasting patterns of polymorphisms at ABO-Secretor gene (FUT٢) and plasma lpha(١،٣)fucosyltransferase gene (FUT٦) in human populations. Genetics ٢٠٠١،١٥٨:٧٤٧-٧٥٦ ٤٣ Marjan Gharagozloo, Abbas Ghaderi. Immunomodulatory Effect of Concentrated Lime Juice Extract on Activated Human Mononuclear Cells. Ethnopharmacology ٢٠٠١, ٧٧:٨٥-٩٠ ٤٤. Mizuki N, Ota M, Katsuyama Y, Yabuki K, Ando H, Yoshida M, Onari K, Nikbin B, Davatchi F, Chams H, Ghaderi A, Ohno S, Inoko H. HLA class I genotyping including HLAB٨٥١ allele typing in the Iranian patients with Behcet?s disease. Tissue Antigen ٢٠٠١, ٥٧:٤٥٧-٤٦٢. ٤٥ Sabri MR, Zohori D, Ghaderi A, Alevian Ghavanini A, Hohanteb J. Borzouee M. Immunologic Factors in acute Rheumatic fever compared to rheumatic heart disease. Iranian Journal of Medical sciences ٢٠٠١, ٢٦:١١٦-١١٩. ٤٦ Khademi B, Shirazi FM, Vasei M, Doroudchi M, Gandomi B, Modjtahedi H, Pezeshki AM, Ghaderi A. The expression of p٥٣, c-erbB-١ and c-erbB-٢ molecules and their correlation with prognostic markers in patients with head and neck tumors. Cancer Lett ٢٠٠٢ ٢٨;١٨٤(٢):٢٢٣-٣٠ ٤٧ Gharagozloo M, Doroudchi M, Ghaderi A. Effects of Citrus aurantifolia concentrated extract on the spontaneous proliferation of MDA-MB-٤٥٣ and RPMI-٨٨٦٦ tumor cell lines in vitro, Phytomedicine ٢٠٠٢, ٩:٤٧٥-٧. ٤٨ Samsami Dehaghani A, Amirzargar A, Farjadian Sh, Ghaderi A. HLA-DQB١ alleles and susceptibility to cervical squamous cell carcinoma in southern Iranian patients. Pathology Oncology Resaerch ٢٠٠٢،٨:٥٨٦١. ٤٩ Ayatolahi M, Malekhossini Z, Ghaderi A. The significance of IgG٤ subclass autoantibody in Pemphigus vulgaris. Eur.J Dermatology, Veronol;ogy ٢٠٠٤ Mar;١٨(٢):٢٤١٢. ٥٠ Doroudchi M, Samsami Dehaghani A, Emad K, Ghaderi A. Placental transfer of human anti-rubella Igg in full-term and pre-term newborns,I nt.J Gyn/OB ٢٠٠٣;٨١:١٥٧-٦٢. ٥١ Kazerooni T, Taalom M, Ghaderi A. Prevalence of H.pylori in hyperemesis grvidarum. In press. Int.J Obstetrics and Gynecology ٢٠٠٢،٧٢:٢١٧-٢٢٠

٥٢-Basiri E, Ardahali SM, Kamali E, Abibagahi M, Sharifi I, Ghaderi A Production and partiacharacterization of monoclonal antibodies to Leishmania. Iranian J med Sciences ٢٠٠٢, ٢٧:٧٥-٧٩ ٥٣ Mizuki N, YAbuki K, Ota M katzuyamaY, Ando H, Nomura H,Funakoshi K, Davatch F, Chams H, Nikbin B, Ghaderi AA, Ohno S, Inoko H Analysis of microsatellite polymorphism around the HLA-B locus in Iranian patients with Behcet's disease. Tissue Antigens. ٢٠٠٢; ٦٠: ٣٩٦-٣٩٩. ٥٤.Ghaderi A, Vasei M, Malek-hossieni SA, Gharesi-fard B, Khodami M, Doroudchi M, Modjtahedi H, The Expression of c-erbB-١ and c-erbB-٢ in Iranian Patients with Gastric Carcinoma. Pathol Oncol Res. ٢٠٠٢;٨(٤):٢٥٢-٦. ٥٥-Kamaisavestani E, Ghaderi A, Gharesifard B. (٢٠٠٢) Production of prostate-specific antigen (PSA) by a breast Cancer cellline SK-Br-٣. Medical J of Islamic Republic of Iran ١٦،٤١-٤٤ ٥٦-Farjadian Sh, Asadi E, pezeshki, Samsami Dehaghani A, Doroudchi M, Tabei SZ, Ghaderi A. High risk HPV type in Iranian cervical carcinoma , Pathology Oncology Research ٢٠٠٣،٩:١٢١-١٢٥ ٥٧ .Kalantary T, Mostafavi H, Pezeshki AM, Farjadian Sh, Doroudchi M, Yaganeh F, Ghaderi AExon ١ polymorphism of CTLA-٤ gene in Iranian patients with Graves? disease. Autoimmunituy ٢٠٠٣, ٣٦،٣١٣-٣١٦ ٥٨-Samsami Dehaghani A Doroudchi M, Ghaderi A. Placental treansfer of tetanus specific IgG in Iranian mothers. The Journal of Maternal-fetal and Neonatal Medicine ٢٠٠٣; ١٤:١٤٧٥٠. ٥٩-Roozbeh J, Serati AR, Ghaderi A, Afsharian R .incidence of arteriovenous thrombosis and the role of anticardiolipin antibodies in hemodialysis patients. International Urology and Nephrology ٢٠٠٣, ٣٥:٢٧٥-٢٨٢ ٦٠-F. Eghtedari, A. Ghaderi, S. Kashef, M. Askari Role of IgE Low-Affinity Receptor (CD٢٣) in Pathogenesis of Nasal Polyp. Iranian Journal of Medical Sciences. ٢٠٠٣, ٢٨،٢٩-٣٢ ٦١-Zolghadri J, Ghaderi A, Alborzi S, Parsanezad ME. Successful pregnancy outcome with IUI in patients with unexplained recurrent miscarriage whose male partners have low score hypo-Osmotic swelling test. Medical journal of Isamic Rep Iran ٦٢-Ghaderi A, F Yaganeh , Talei A,Pezeshki,A,Samsami A,Kanatary T, Doroudchi M, Exon١ ctla٤ gene polymorphism in breast cancer . Breast Cancer Res Treat. ٢٠٠٤ Jul;٨٦(١):١-٧. ٦٣. Ghaderi, A., Doroudchi, M., Kimura, H. A polymorphic haplotype in BRCA١ gene with different frequency in Iranian, Japanese, and African normal individuals. Submitted ٦٤-Davar Amani,Jaleh Zolghadri, Alamtaj Samsami, Abdulmohamad Pezeshki Abbas Ghaderi. The promoter region (-٨٠٠, -٥٠٩) polymorphisms of transforming growth factor-

beta١ (TGF-beta١) gene and recurrent spontaneous abortion.J Reproductive Immunology ٢٠٠٤, l ٦٢/١-٢ :١٥٩-١٦٦ ٦٥- Yousefi-pour GA, Izadi S, Ghaderi A. Immunological correlates of adult onset idiopathic generalized tonic-clonic epilepsy among Iranian adults before and after sodium valproate treatment Iranian J Immunology ٢٠٠٤،١:١٠٥-١١٠ ٦٦-Vahedi F, Joubeh S, Doroudchi M,Abdollahi B, Ghaderi A Detection of Rheumatoid Factors in Sera and Biopsy Lesions of Vitiligo Patients. Iranian J Immunol. ٢٠٠٤،١:٤٨-٥٥ ٦٧-Ali Derakhshan, Masoumeh Mohkam, Abbas Ghaderi, Ghamar Hosseini Alhashemi, Mohammad Hossein Fallahzadeh Tumor Markers in Patients Undergoing Hemodialysis and Kidney Transplantation. Iranian J Immunol. ٢٠٠٤،١:٤١-٤٧ ٦٨-Farjadian S, Naruse T, Kawata H, Ghaderi A, Bahram S, Inoko H. Molecular analysis of HLA allele frequencies and haplotypes in Baloch of Iran compared with related populations of Pakistan. Tissue Antigen ٢٠٠٤ Nov;٦٤(٥):٥٨١-٧ ٦٩-Kasef S, Amin R, Ayatollahi, Ghaderi A. Anticardiolipin antibody in juvenile rheumatoid Artheritis and systemic Lupus erythematosus. Iranian Journal Immunology ٢٠٠٤ ١١٨-١٢٤ ٧٠-Doroudchi M,Samsami Dehaghani A, Ghaderi A. Preferential placental transfer of Helicobacter pylori specific IgG J Maternal-Fetal and neonatal Medicine ٢٠٠٤, J Matern Fetal Neonatal Med. ٢٠٠٤ Nov;١٦(٥):٢٩٧-٣٠١ ٧١-Zahra Mojtahedi, Gholamhossein R. Omrani,, Mehrnoosh Doroudchi, Abbas Ghaderi, ctla-٤ +٤٩ A/G polymorphism is associated with predisposition to type ١ diabetes in Iranians Diabetes Research and Clinical Practies ٢٠٠٥, ٦٨:١١١-٦. ٧٢-Razmkhah M , Talei A , Doroudchi M , Khalili-Azad T , Ghaderi A SDF-١ alleles and susceptibility to breast cancer Cancer letters ٢٠٠٥: ٢٨;٢٢٥(٢):٢٦١-٦ ٧٣-Marjan Gharagozloo, Mehrnoush Doroudchi, Shirin Farjadian Abdul Mohammad Pezeshki, Abbas Ghaderi The Frequency of CCR٥∆٣٢ and CCR٢-٦٤I alleles in southern Iranian normal population Immunology Immunol Lett. ٢٠٠٥ Jan ٣١;٩٦(٢):٢٧٧-٨١. ٧٤-Sharifzadeh S, Owji SM, Pezeshki AM, Malekhossini Z, , Kumar PV, Ghayumi SMA Ghaderi A. I Establishment and characterization of a human large cell lung cancer cell line wit neuroendocrine differentiation Pathology Oncology Research. ٢٠٠٤;١٠(٤):٢٢٥-٣٠. ٧٥-Rajaee A, Ebrahimi A, Fotouhi Ghiam A, Kalantari T, Ghaderi A Exon-١ Polymorphism of ctla-٤ Gene is not associated with Systemic Sclerosis in Iranian Patients . Rheumatology International. Rheumatol Int. ٢٠٠٥ Sep ٢٨;:١-٦ ٧٦-Pezeshki, A.. Sari-Aslani, F., Ghaderi, A., Doroudchi, M. p٥٣ codon ٧٢ polymorphism in Basal cell carcinoma of Skin. Pathology Oncology Research ٢٠٠٥. In Press.

٧٧-Samsami Dehaghani A, Doroudchi M, Kalantari T , Pezeshki AM , Ghaderi A Heterozygosity in ctla-٤ gene increases susceptibility to severe pre-eclampsia Int.J Gynecology and Obstetrics ٢٠٠٥ ; ٨٨:١٩-٢٤ ٧٨-Zahra Mojtahedi, Shirin Farjadian, Abbas Ghaderi, Does Autoantigen Adminstration inhibit Recurrence of Type ١ Diabetes in Transplanted Islets (A Hypothesis). Medical hypothesis ٢٠٠٥, ٦٤:٩٨٦-٩٨٨ ٧٩-Akbar Rajaee, Mohammad Ali Nazarinia, Seyed Modjtaba Hakim, Mitra Amini, Maryam Ayatollahi, Abbas Ghaderi. Anticardiolipin Antibody in Patients with Behçet's Disease with and Without Vascular Thrombosis. Iranian J of Immunology ٢٠٠٤،١:١١١-١١٧ ٨٠- Marjan Gharaghouslo and Abbas Ghaderi. Coincident natural selection of CCR٥D٣٢ and C٢٨٢Y in Europe:to be or not to be?. Journal of Genetics ٢٠٠٥, ٨٤:٤٧-٤٨ ٨١-Mojtahedi Z, Ghaderi A. Role of interleukin-١٨ in allergy and autoimmunity: An explanation for the hygiene hypothesis Med Hypotheses. ٢٠٠٥;٦٥(٢):٣٠٥-٧. ٨٢-Razmkhah M, Doroudchi M, Ghayumi SM, Erfani N, Ghaderi A Stromal cell-derived factor-١ (SDF-١) gene and susceptibility of Iranian patients with lung cancer. Lung Cancer. ٢٠٠٥, ٢٠٠٥ ٢٨;٢٢٥(٢):٢٦١-٦. ٨٣-Fattahi MJ, Pezeshki AM, Emad M, Lohrasb MH, Shamsedin A, Ghaderi A, Doroudch M. ctla-٤ A٤٩G polymorphism in vitiligo patients. Iranian Journal of Immunology ٢٠٠٥٫٢،٩٧١٠٢ . ٨٤-Dawar Amani ,Alamtaj Samsami Dehaghani , Jaleh Zolghadri Fatemeh Ravangard , Norrio Niikawa, Ko-ichiro Yoshiura , Abbas Ghaderi Screening of the of transforming growth factor-β١ (TGF-β١) gene in women with recurrent spontaneous abortion. Journal Reproductive Immunology ٢٠٠٥ Dec;٦٨(١-٢):٩١-١٠٣ ٨٥-SMA Ghayumi, Samrad Mehrabi, Mehrnossh Doroudchi, Abbas Ghaderi. Diagnostic value of tumor markers for differentiating malignant and benign pleural effusions of Iranian patients. Pathology Oncology Research ٢٠٠٥;١١(٤):٢٣٦-٤١ ٨٦-Sirous Naeimi, Alireza Fotouhi Ghiam, Alamtaj Samsami Dehaghani, Dawar Amani, Abbas Ghaderi . Interleukin-١٨ promoter gene polymorphisms and Recurrent Spontaneous Abortion (RSA) .European Journal Obstetrics and gynecology and Reproductive Biology (In Press) ٨٧-Naghiballhossini F, Pakdel Z, Ghaderi A, Saberifirozi M. Effective Production of Carcinoembryonic Antigen by Conversion of the Membrane-bound Into a Recombinant Secretory Protein by Site-specific Mutagenesis. Pathol Oncol Res. ٢٠٠٥;١١(٤):٢١١-٧

٨٨- Zahra Mojtahedi, Sirous Naeimi, Shirin Farjadian, Gholamhossein R. Omrani,Abbas Ghaderi Association of IL-١٨ promoter polymorphisms with Predisposition to type ١ diabetes. Diabetes Medicine: Diabet Med. ٢٠٠٦ Mar;٢٣(٣):٢٣٥-٩. ٨٩.Erfani N, Razmkhah M, Talei A, Pezeshki, Doroudchi M, Monabati A, Ghaderi A. Cytotoxic T-lymphocyte antigen-٤ promoter variants in breast cancer . Cancer Genet Cytogenet. ٢٠٠٦ Mar;١٦٥(٢):١١٤-٢٠. ٩٠-Kamran B. Lankarani, Ashraf Karbasi, Tahereh Kalantari, Hooman Yarmohammadi, Mehdi Saberi-Firoozi, Mahvash Alizadeh-Naeeni, Ali R. Taghavi, Mahammad R. Fattahi and Abbas Ghaderi. Analysis of CTLA-٤ gene polymorphisms in patients with Ulcerative Colitis. J Gastroenterol Hepatol. ٢٠٠٦ Feb;٢١(٢):٤٤٩-٥٣. ٩١ – Shirin Farjadian, Farhad Akbari Moghadam , Abbas Ghaderi HLA class II gene polymorphisms in Parsees and Zoroastrians of Iran. Int J Immunogenet. ٢٠٠٦ Jun;٣٣(٣):١٨٥-٩١. ٩٢-Shohreh Almasi , Nasrollah Erfani , Zahra Mojtahedi , Akbar Rajaee, Abbas Ghaderi Association of CTLA-4 gene promoter polymorphisms with systemic sclerosis in Iranian population ٢٠٠٦: Genes Immun. ٢٠٠٦ Jul;٧(٥):٤٠١-٦. Epub ٢٠٠٦ Jun ١٥ ٩٣-Zahra Mojtahedi, Shahram Baharvand Ahmadi, Mahboobeh Razmkhah, Tahereh Khalili Azad, Akbar Rajaee, Abbas Ghaderi..Association of chemokine receptor ٥ (CCR٥) ∆٣٢ mutations with Behcet's disease is dependent on gender in Iranians patients. Clinical Experimental rheumatology. ٢٠٠٦ Sep-Oct;٢٤(٥ Suppl ٤٢):S٠٩١-٤. ٩٤- Kashef S, Ghaedian MM, Rajaee A, Ghaderi A .Dyslipoproteinemia during the active course of systemic lupus erythematosus in association with anti-double-stranded DNA (antidsDNA) antibodies. Rheumatol Int. ٢٠٠٦ Aug ٣٠; [Epub ahead of print] ٩٦-Shirin Farjadian , Abbas Ghaderi. .Iranian Lurs Genetic Diversity: An Anthropological View Based on HLA Class II Profiles. Iran.J. Immunol, ٢٠٠٦, ٣،١٠٦-١١٣ ٩٧-Varamini P, Doroudchi M, Mohagheghzadeh A, Soltani M, Ghaderi A. Cytotoxicity evaluation of four Haplophyllum species on various tumor cell lines J Therapeutical biology ٢٠٠٧, ٤٥:٢٩٩-٣٠٢ ٩٨-Hadinia A, Hossieni SV, Erfani N, Saberi-Firozi M Fatahi MJ, Ghaderi A Ctla-٤ gene promoter and exon ١ polymorphisms in Iranian patients with gastric and colorectal cancers. J Gasteroentrology and hepatology (In Press ٢٠٠٧) ٩٩--Baharak Khadang, Mohammad Javad Fattahi, Abdolrasol Talei, Alamtaj Samsami Dehaghani, Abbas Ghaderi. Investigation of P٥٣ gene codon ٧٢ polymorphisms in Iranian patients with breast cancer Cancer Genetics and cytogenetics ٢٠٠٧ Feb;١٧٣(١):٣٨-٤٢ ١٠٠-Tamizifard B, Bagheri-Lankarani K, Narrmi Sm Rismankar-zade M, Taghavi A, Ghaderi A.-Polymorphism of the promoter region of C-٥٠٩T of transforming growth factorbeta١ gene and ulcerative colitis. Arch Iran Med. ٢٠٠٧ Apr;١٠(٢):١٧١-٥.

١٠١-Kavvoura FK, Akamizu T, Awata T, Ban Y,Chistiakov DA, Frydecka I, Ghaderi A,Gough SC,Hiromatsu Y,Ploski R,Wang PW, Ban Y,Bednarczuk T,Chistiakova EI, Chojm M, Heward JM, Hiratani H,Juo SH, Karabon L,Katayama S, Kurihara S, Liu RT,Miyake I, Omrani GH, Pawlak E, Taniyama M,Tozaki T,Ioannidis JP CTLA-٤ Gene Polymorphisms and Autoimmune Thyroid Disease: A Meta Analysis. J Clin Endocrinol Metab. ٢٠٠٧ May ١٥ ١٠٢. Farjadian S Ghaderi A. HLA class II Genetic Diversity in Arabs and Jews of Iran. Iran J Immunol. ٢٠٠٧ , ٤:٨٥-٩٣

Manuscript Submitted (٢٠٠٦) ١-Mousavi AR, Nikseresht AR, Arandi N, Borhani Haghighi A, Ghaderi A Intercellular adhesion molecule-١ gene polymorphism in Iranian patients with multiple sclerosis. ٥-Alamtaj Samsami Dehaghani,, Alireza Fotouhi Ghiam, Marjan Hosseini, Sareh Mansouri,, Abbas Ghaderi, Factors Influencing Serum Concentration of CA١٢٥ and CA١٥-٣ in Iranian Healthy Menopausal Women

CONGRESS ATTENDANCE ١.Ghaderi,A.A. and Stanworth,D.R. Use of synthetic εchain peptides in the study of the mode of interaction of soluble FcεRII (IgE-BF). Abstract, ٧th Int.Congress of Immunology. Berlin,Germany, ١٩٨٩. ٢.Ghaderi,A.A. and Stanworth,D.R. Monoclonal antibody specific for IgE binding factor (IgE-BF). Abstract, British Society for Immunology,London, Nov.,١٩٨٩. ٣.Ghaderi,A.A., Jones,V.M., Stanworth,D.R. Mast cell triggering by IgE binding factor (IgE-BF). Abstract,British Society for Allergy and Clinical Immunology, Edinburgh, Scotland, Sept.١٩٨٩. ٤.Ghaderi,A.A., Guadernack,G., Stanworth,D.R. Dual recognition of HLA-DR/DP induced immunosuppression. Abstract, European Federation of Immunological Societies, Edinburgh, Scotland,Sept.١٩٩٠. ٥-Ghaderi.A.A and Doroudchi.M. Elevation of CD٢١/CD٢٣ positive peripheral blood mononuclear cells in children with atopic dermatitis. Abs. Accepted for oral presentation in ١٢th.European Immunology Meeting, ١٤-١٧ June ١٩٩٤, Barcellona, Spain. ٦-. Ghaderi,A.A and M.H.Agahi. Determination of a shared epitope on cells from acute myelogenic leukemia (AML) and T-acute lymphoblastic leukemia (T-ALL). Accepted for presentation in ١٢th European Immunology Meeting,June ١٤-١٧،١٩٩٤,Barcellona, Spain. ٧. Amirghofran,Z., Tabei,S.Z., Ghaderi,A.A. Cross-Linking of CD٣٨ molecule induced expression of HLA-DRand IL-٢R on human thymocytes. Abs.Accepted for presentation in ١٢th.European Immunology Meeting, June ١٤-١٧،١٩٩٤,Barcellona, Spain.

٨. Ghaderi,AA ,. Amirzargar,A, Shokri,F., Jobson,S. ,Mytilineos,J., Scherer,S., Ala,F. Immunology Departments of Shiraz (IR) Ahwaz (IR), Tehran (IR), Birmingham (GB) and Heidelberg (D). Analysis of HLA-DRB١ and DQB١ allele and haplotype frequencies in ٢٧ Iranian B-cell chronic lymphocytic leukemia (B-CLL) patients. HISTOCOMPATIBILITY CONFERENCE JUNE ٩-١٢،٩٦, PARIS FRANCE. ٩. Ghaderi, AA., Joubeh,S., Davatolhagh,Z., Vahedi,F., Dalyer,S. Departments of Immunology and Dermatology,Shiraz University of Medical Sciences, Shiraz-Iran. HISTOCOMPATIBILITY CONFERENCE JUNE ٩-١٢،٩٦, PARIS FRANCE. ١٠. Scherer Sabine, Amirzargar,A., Mytilineos,J., Ghaderi,AA., Farjadian,S., Marburg,S., Sucker,T., Opelz.G.-HLA class II antigen frequencies and haplotype associations in ٩٦ unrelated Iranian individuals. Immunology Departments of Heidelberg (Germany) Ahwaz (Iran) and Shiraz (Iran). HISTOCOMPATIBILITY CONFERENCE JUNE ٩-١٢،٩٦, PARIS FRANCE. ١١. Amirzargar A., Mytilineos,J., Scherer,S., Yousefipour,GH., Ghaderi,A. Farjadian,S., Opelz, G. Analysis of HLA DRB١,DRB٢,DRB٣,DRB٤,DQB١ and DQA١ frequencies and Haplotypes in ٤٣ Iranian Multiple Sclerosis patients, Immunology Departments of Ahwaz (Iran) Heidelberg (Germany) and Shiraz (Iran). HISTOCOMPATIBILITY CONFERENCE JUNE ٩-١٢،٩٦, PARIS FRANCE. ١٢. Leukocyte immunotherapy in recurrent spontaneous abortion (RSA): a preliminary report from Iran Gharesi-fard B١, Zolghadri J٢ and Ghaderi A. ١٤th European Federation of Immunological society , Poznan Poland, September ٢٣-٢٨،٢٠٠٠ ١٣. Ghaderi, A.A., Ardehali, S., Habib-Agahi, M., Doroudchi, M., Basiri, E. A seroepidemiological study of leishmaniasis in nomads of southern Iran. The First World Congress on Leishmaniosis, Istanbul, Turkey. Published in: Acta Parasitologica Turcica (١٩٩٧) Vol ٢١(supplement ١): page ١٣٦. ١٤. Ghaderi, A.A., Ardehali, S., Basiri, E., Doroudchi, M., Habib-Agahi, M., Kamali, F. Production of hybridomas secreting antibody to Leishmania. The First World Congress on Leishmaniosis, Istanbul, Turkey. Published in: Acta Parasitologica Turcica (١٩٩٧) Vol ٢١(supplement ١): page ٣٥. ١٥. Doroudchi, M., Kremer, K., Basiri, E.A., Kadivar, M.R., Ghaderi, A.A., van Soolingen, D. IS٦١١٠-RFLP typing of Mycobacterium tuberculosis isolates of Fars province. The Fourteen Congress of Tuberculosis and Lung Diseases, October ١٢-١٤, ١٩٩٨, Kashan, Iran.

١٦. Samsami Dehaghani, A., Doroudchi, M., Emad, K., Ghaderi,A.A. Investigation of transplacental passage of rubella antibodies in women from southern Iran. ١١th International Congress of Immunology, July ٢٢-٢٧, ٢٠٠١, Stockholm, Sweden. ١٧. Doroudchi, M., Samsami Dehaghani, A., Emad, K., Ghaderi, A.A. Detection of IgG antirubella antibodies in two different age groups of Iranian population. ١١th International Congress of Immunology, July ٢٢-٢٧, ٢٠٠١, Stockholm, Sweden.

١٨. Gharagozloo, M., Doroudchi, M., Ghaderi, A.A. Immunomodulatory effect of concentrated lime juice extract on activated human mononuclear cells. ١١th International Congress of Immunology, July ٢٢-٢٧, ٢٠٠١, Stockholm, Sweden. ١٩. Pezeshki, A.M., Vasei, M., Talei, A., Farjadian, S., Doroudchi, M., Gharesi-Fard, B., Ghaderi, A. Molecular and immunohistochemical analysis of p٥٣ in primary breast cancer. ١١th International Congress of Immunology, July ٢٢-٢٧, ٢٠٠١, Stockholm, Sweden. ٢٠. Gharagozloo M., Doroudchi M., Ghaderi A. Effects of Citrus aurantifolia (Lime) concentrated extract on the spontaneous proliferation of MDA-MB-٤٥٣ and RPMI-٨٨٦٦ tumor cell lines in vitro. ١٨th UICC International Cancer Congress, June ٣٠-July ٥, ٢٠٠٢, Oslo, Norway. ٢١. Yeganeh F., Pezeshki A.M., Talei A., Samsami Dehaghani A., Doroudchi M., Farjadian S., Kalantari T. , Ghaderi A. ctla-٤ gene polymorphism in Southern Iranian women with breast cancer. ١٨th UICC International Cancer Congress, June ٣٠-July ٥, ٢٠٠٢, Oslo, Norway. ٢٢. Mohammadalizadeh Shirazi F., Khademi B., Vasei M., Doroudchi M., Modjtahedi H., Ghaderi A. The expression of p٥٣, c-erbB-١ and c-erbB-٢ molecules and their correlation with prognostic markers in patients with head and neck tumor. ١٨th UICC International Cancer Congress, June ٣٠-July ٥, ٢٠٠٢, Oslo, Norway.