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Dendrimers for Drug Delivery
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Available July 2018
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Editors: Anil K. Sharma, Mpharm Delhi Institute of Pharmaceutical Sciences & Research, University of Delhi, India
Raj K. Keservani, MPharm Sagar Institute of Research and Technology-Pharmacy, Bhopal With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals. Key features: • Presents a concise and informative introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers • Looks at computational approaches to elucidate dendrimers, embracing classification, synthesis, and nomenclature with simulation • Explores issues related to applications relevant to biological systems in particular, providing an abundance of information about dendrimers and their biocompatibility and toxicity • Covers dendrimers for controlled release drug delivery and considers dendrimers’ ability to respond to alterations in pH, temperature, light, etc. • Describes the uses of dendrimers for oral drug delivery Explores different aspect of dendrimer-mediated gene delivery • Looks at customized applications of dendrimers as nanocarriers for anticancer drugs • Describes the dendrimeric architecture for effective antimicrobial therapy
CONTENTS Preface PART I: PREAMBLE OF NANOMETRIC ARTIFACTS: DENDRIMERS 1. Dendrimers: Branched Nanoarchitectures and Drug Delivery Raj K. Keservani, Swarnali Goswami, and Anil K. Sharma 2. Dendrimers: A Tool for Advanced Drug Delivery Patrícia Mazureki Campos, Juliana Palma Abriata, Abayomi Tolulope Ogunjimi, Juliana Maldonado Marchetti, and Robert Lee 3. Dendrimers: General Features and Applications Durgavati Yadav, Kumar Sandeep, Shivani Srivastava, and Yamini Bhusan Tripathi 4. Computational Approach to Elucidate Dendrimers Gurpreet Kaur PART II: ADVANCEMENTS IN DENDRIMER APPLICATIONS 5. An Overview of Dendrimers and Their Biomedical Applications Nirupam Das, Piyoosh A. Sharma, Ankit Seth, Rahul Maheshwari, Muktika Tekade, Sushant K. Shrivastava, and Rakesh K. Tekade 6. Dendrimers for Controlled Release Drug Delivery Phung Ngan Le, Dai Hai Nguyen, Cuu Khoa Nguyen, and Ngoc Quyen Tran 7. Dendrimers in Targeted Drug Delivery Ankit Seth, Piyoosh Sharma, Rahul Maheshwari, Muktika Tekade, Sushant K. Shrivastava, and Rakesh K. Tekade 8. Dendrimers in Oral Drug Delivery Sougata Jana, Joyita Roy, Nilofer Jasmin, Bibek Laha, and Sudipta Das PART III: DENDRIMERS IN SPECIALIZED THERAPEUTICS 9. Dendrimers in Gene Delivery Piyoosh A. Sharma, Rahul Maheshwari, Muktika Tekade, Sushant K. Shrivastava, Abhay S. Chauhan, and Rakesh K. Tekade 10. Dendrimers as Nanocarriers for Anticancer Drugs Michał Gorzkiewicz and Barbara Klajnert-Maculewicz
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11. Dendrimeric Architecture for Effective Antimicrobial Therapy Canadian office: 3333 Mistwell Crescent Ramadoss Karthikeyan, Oruganti Sai Koushik, and Oakville, Ontario L6L 0A2 Canada Palanirajan Vijayaraj Kumar Tel: 289-937-6300, Fax: 866-222-9549 Email:
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Contents continued on side 2
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Dendrimers for Drug Delivery
ABOUT THE EDITORS Anil K. Sharma, MPharm is a lecturer at the Delhi Institute of Pharmaceutical Sciences & Research, University of Delhi, India. He has published 25 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals as well as ten book chapters. His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDs), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology. He graduated with a degree in pharmacy from the University of Rajasthan, Jaipur, India, and received a Master of Pharmacy (MPharm) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India, with a specialization in pharmaceutics. Raj K. Keservani, MPharm, has more than seven years of academic teaching experience at various institutes in India in pharmaceutical science. He has published 25 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals, ten book chapters, and two co-authored books. He is also active as a reviewer for several scientific international journals. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDs), transdermal drug delivery/ drug delivery, health science/life science, and biology/cancer biology/neurobiology. Mr. Keservani earned his BPharm at the Department of Pharmacy at Kumaun University, Nainital, India, and received his MPharm from the School of Pharmaceutical Sciences at Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India, with a specialization in pharmaceutics.
14 color and 25 b/w illustrations 448 pages with index. ISBN hard: 978-1-77188-662-8. Cat#: N12017 ISBN ebook: 978-0-203-371315-0. Cat#: NE12836 $169.95 US | £131.00 hardback. July 2018.
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