Abstract. The effect of cholecystokinin octapeptide (CCK-8) was studies on the release of growth hormone (GH) from perifused medial basal hypothalami.
Effect Release Pituitary
of Cholecystokinin of Growth and
Octapeptide
Hormone
Hypothalamus
in Perifused of the Goat Tsutomu
Faculty
on the
HASHIZUME and Shigeto
of Agriculture,
Iwate University,
KANEMATSU
Morioka-shi
020
(Received October 26, 1990) Abstract The effect of cholecystokinin octapeptide (CCK-8) was studies on the release of growth hormone (GH) from perifused medial basal hypothalami (MBH) and/or adenohypophyses of goats in a sequential double chamber perifusion system. The mean GH concentrations in perifusion groups containing pituitary fragments alone with media containing 10-6, 10-7 and 10-8 M CCK-8 for 90 min significantly increased during the treatments by 76% (P
