M.;Castiglione Gertsch, R.D.;Gelber, A.S.Coates, and. A.Goldhirsch, (2007). ... Biochem., 22(2): 17-31. McMillan, J.; R.C.;Kinney, D.M.;Ranly, S.; Fatehi-Sedeh,.
EFFECT OF VITAMIN E INJECTION ON RATS INDUCED WITH BREAST CANCER AND THEIR RELATION TO BONE DISTURBANCE Journal J. Biol. Chem. Environ. Sci., 2013, Vol. 8(3):351-367 www.acepsag.org
Nadia, M. Abdel-Moein1; Faten, M. Abo ElElla1; Mervat, H. Youssef2; Amal, M. Ahmed2; Mamdouh, T. Eassawy2 and Khaled Y. Farroh2 1
Biochemistry Department, Faculty of Agriculture, Cairo University 2 Regional Center for Food and Feed, Agriculture Research Center, Giza, Egypt
ABSTRACT The present study was carried out to study the inhibitory effect of vitamin E on breast cancer induced by N-methyl-N-nitrosourea (MNU) in female Sprague-Dawley rats. The effect of vitamin E on serum levels of tumor marker Carcinoembryonic antigen (CEA), estrogen, progesterone hormones, alkaline phosphatase (ALP) activity, red blood cells (RBCs) count, white blood cells (WBCs) count and hemoglobin were determined. In additional calcium, inorganic phosphates, femoral thickness, femoral length, breaking force, femoral wet weight, bone volume and bone density were evaluated to study the effects of vitamin E on bone. The results showed that the serum progesterone, hemoglobin levels and RBCs count were significantly higher (p
