Environmental exposure to polycyclic aromatic ...

6 downloads 0 Views 370KB Size Report
(COFs) during household cooking, because stir- frying is a popular cooking method in China, and Chinese- style cooking produces large quantities of COFs.4 ...
|

Received: 30 August 2017    Accepted: 6 February 2018 DOI: 10.1111/ina.12453

ORIGINAL ARTICLE

Environmental exposure to polycyclic aromatic hydrocarbons, kitchen ventilation, fractional exhaled nitric oxide, and risk of diabetes among Chinese females J. Hou1,2 | H. Sun1,2 | Y. Zhou1,2 | Y. Zhang1,2 | W. Yin1,2 | T. Xu1,2 |  J. Cheng1,2 | W. Chen1,2 | J. Yuan1,2 1 Department of Occupational and Environmental Health, Huazhong University of Science and Technology, Wuhan, China 2

Abstract Diabetes is related to exposure to polycyclic aromatic hydrocarbons (PAHs), inflamma-

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

tion in the body, and housing characters. However, associations of urinary monohydroxy-­

Correspondence Jing Yuan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Email: [email protected]

regression models. Among women with self-­cooking meals, urinary OH-­PAH levels

Present address Huizhen Sun, Hubei Center for Disease Control and Prevention, Wuhan, China

exhaust fans/hoods had a 52% decrease in the risk of diabetes (OR: 0.48, 95% CI: 0.27,

Funding information Public Sector Program of National Environmental Protection of the People’s Republic of China, Grant/Award Number: 201409081; Key Project of the National Natural Science Foundation of China, Grant/ Award Number: 91543207; National Key Research and Development Plan of China, Grant/Award Number: 2016YFC1303903

explained by an increase in the PAH body burden and higher inflammatory responses.

PAHs (OH-­PAHs) or fractional exhaled nitric oxide (FeNO) with diabetes risk in relation to housing characters are unclear. In this study, 2645 individuals were drawn from the baseline survey of the Wuhan-­Zhuhai Cohort Study. Associations of diabetes with ­urinary OH-­PAHs or FeNO among cooking participants were estimated using logistic were positively associated with diabetes risk (P