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Chapter 7. From DNA to Protein: How Cells. Read the Genome. Essential ... Compe on is a worldwide Synthe c Biology compe on aimed at ... Page 12 ...
Essential Cell Biology
Third Edition
Chapter 7 From DNA to Protein: How Cells Read the Genome
Copyright © Garland Science 2010
The Interna*onal Gene*cally Engineered Machine (iGEM) Compe**on is a worldwide Synthe*c Biology compe**on aimed at undergraduate university students.
130 Teams
In 2010!
(but no UCSB )
Summary of Achievements
Characterization of new mammalian activators & repressors
Complex mammalian logic circuit
Computational design of multicellular behavior
Adhesion of mammalian cells
Engineering of Notch-Delta communication system
Figure 7-1 Essential Cell Biology (© Garland Science 2010)
NOTE: [mRNA] weakly correlates
with [protein]
Figure 7-2 Essential Cell Biology (© Garland Science 2010)
DNA Microarrays Can be Used to Measure mRNA species Abundance
There are two primary differences between DNA and RNA
Figure 7-3 Essential Cell Biology (© Garland Science 2010)
Figure 7-5 Essential Cell Biology (© Garland Science 2010)
Table 7-4 Essential Cell Biology (© Garland Science 2010)
Figure 7-7 Essential Cell Biology (© Garland Science 2010)
Efficient transcription enables many transcripts to be made from one gene simultaneously
Figure 7-8 Essential Cell Biology (© Garland Science 2010)
Table 7-1 Essential Cell Biology (© Garland Science 2010)
In bacteria sigma factors direct RNApol to promoters
Figure 7-9 Essential Cell Biology (© Garland Science 2010)
The sequence features of promoters are conserved
Figure 7-10 Essential Cell Biology (© Garland Science 2010)
Consensus -10 and -35 sequences
Figure 7-11 Essential Cell Biology (© Garland Science 2010)
Table 7-2 Essential Cell Biology (© Garland Science 2010)
Figure 7-12 Essential Cell Biology (© Garland Science 2010)
Figure 7-13 Essential Cell Biology (© Garland Science 2010)
Figure 7-14 Essential Cell Biology (© Garland Science 2010)
Figure 7-16a Essential Cell Biology (© Garland Science 2010)
Figure 7-16b Essential Cell Biology (© Garland Science 2010)
Figure 7-17 Essential Cell Biology (© Garland Science 2010)
Figure 7-18 Essential Cell Biology (© Garland Science 2010)
Figure 7-20 Essential Cell Biology (© Garland Science 2010)
Figure 7-21 Essential Cell Biology (© Garland Science 2010)
Figure 7-22 Essential Cell Biology (© Garland Science 2010)
Figure 7- 23a Essential Cell Biology (© Garland Science 2010)
Figure 7-23b Essential Cell Biology (© Garland Science 2010)
Figure 7-24 Essential Cell Biology (© Garland Science 2010)
Figure 7-25 Essential Cell Biology (© Garland Science 2010)
Figure 7-28 Essential Cell Biology (© Garland Science 2010)
Figure 7-29 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
Figure 7-29 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
Figure 7-30 Essential Cell Biology (© Garland Science 2010)
Figure 7-31 Essential Cell Biology (© Garland Science 2010)
Figure 7-32 Essential Cell Biology (© Garland Science 2010)
Figure 7-33 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-33 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-33 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-33 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-34 Essential Cell Biology (© Garland Science 2010)
Figure 7-35 (part 1 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-35 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-35 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-35 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-35 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)
Figure 7-36 Essential Cell Biology (© Garland Science 2010)
Figure 7-37 Essential Cell Biology (© Garland Science 2010)
Figure 7-37 (part 1 of 3) Essential Cell Biology (© Garland Science 2010)
Figure 7-37 (part 2 of 3) Essential Cell Biology (© Garland Science 2010)
Figure 7-37 (part 3 of 3) Essential Cell Biology (© Garland Science 2010)
Figure 7-38 Essential Cell Biology (© Garland Science 2010)
Ribosomes are recruited to the Kozak Sequence
Table 7-3 Essential Cell Biology (© Garland Science 2010)
Figure 7-40 Essential Cell Biology (© Garland Science 2010)
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