GeF-seq ChAP-chip ChAP-seq GeF-seq ChAP-chip

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yjbB. yjbC. spxA. mecA. coiA. pepF. yjbL yjbM. ppnKA. yjbO. yjbQ. tenA. tenI ..... 2,630,000bp. 2,640,000bp. antE. yqeW. rpsT. yqzM. comER sda. yqeD. sigA.

10,000bp

dnaA

recF yaaA

dnaN

20,000bp

30,000bp

40,000bp

bofA yaaB gyrB

gyrA

guaB

dacA

pdxS

pdxT

serS

trnSL-Ser1

yaaC

dck

54

dgk

yaaH

dnaX

yaaK recR

csfB

yaaL

xpaC

yaaN

yaaO

tmk

yaaQ yaaR

holB

yaaT

yabA

yabC yazA

yabB

metS

yaaI

yabD

yabE

abrB

472

28

577

GeF-seq

ChAP-seq

ChAP-chip

23

tadA

60,000bp

70,000bp

80,000bp

90,000bp

spoIIE rnmV

ksgA

yabG

veg

sspF ispE

purR

yabJ

gcaD

prs

ctc

pth

yabK mfd

spoVT

661

yabM

yabN

yabO yabP yabQ

divIC

561

yabR

yabS

99

yabT

tilS

hprT

ftsH

coaX

257

hslO

yacD

cysK

pabB

pabA

pabC

sul

folB folK

dusB yazB

lysS

672

GeF-seq

ChAP-seq

ChAP-chip

127

spoVG

110,000bp

rrnW-23S

ctsR rrnW-5S

mcsA

mcsB

clpC

radA

disA

yacL

ispD

120,000bp

ispF

cysE

cysS

mrnC

rlmB

yacP

secE rpmGB nusG

sigH

687

rpsL rplK

rplA

rplJ

rplL

ybxB

639 659

196

140,000bp

rpoB

105 488

rpoC

404

rplGB

rpsG

fusA

tufA

ybaC

rpsJ rplC

rplD

rplW rplB

201

rpsS rplV rpsC

rplP

rpsQ rpmC rplNA rplX rplE

rpsH rpsNA

rplF

rplR rpsE

rplO rpmD

695

secY

adk

infA rpsM ybzG rpmJ rpsK

mapA

rpoA

647

rplQ

515

GeF-seq

ChAP-seq

ChAP-chip

698

gltX

130,000bp

160,000bp

rplQ

ybxA

ybaE

ybaF

truA

rplM

rpsI

ybaJ

ybaK

cwlD

salA

170,000bp

180,000bp

kbaA

gerD

ybaR

190,000bp

ybaS

ybaN

sigW

ybbA

feuC

feuB

feuA

ybbB

ybbC

ybbD

ybbE

ybbF

ybbH

murQ

ybbJ

rsiW

ybbP

ybbR

glmM

ybbK

GeF-seq

ChAP-seq

ChAP-chip

40

210,000bp

glmS

adaA

adaB

ndhF

ybcC

ybcF

ybcH ybcI

220,000bp

ybzH

ybcL

ybcM

skfB skfA

skfC

skfE

alkA

ChAP-chip ChAP-seq

skfG

skfH

ybdG

ybdJ

ybdK

ybzI

ybdM

364

GeF-seq

skfF

230,000bp

612 619

110

79

ybdO

ybdN

ybxG

ybxH csgA

cypC

ybxI

212

240,000bp

ybeC

ybyB

271

504 222

ybeF ybfA

glpQ

glpT

ybfB

purT

ybfE

ybfF

ybfG

ybfH

mpr

ybfJ

ybfK

pssA

ybfM

psd

ybfN ybfO

ybfI

538

656

520

260,000bp

ybfO

ybfP

ybfQ

ybgA

gltP

nagP

ybgB

270,000bp

ilvE

glnJ

nagBB

ybgF

ybgG

glnT

glnL

ycbC

ycbD

280,000bp

gudP

gudD

ycbG

garD

ycbK rtpA

ycbJ

ycbL

ycbM

290,000bp

ycbN

ycbO

cwlJ

glsA

phoD yczK

ycbR

tatCD tatAD

ycbU

ycbP

ansZ

pcp

lmrA

211 104

114

yccF

yczC

177 193

49

natA

natK

natB

yccK

natR

352

ycdA

525

GeF-seq

ChAP-seq

ChAP-chip

629

lmrB

estA

310,000bp

ycdB

ycdC

rapJ

ycdA

ycdF

ycdG

adcA

adcC

320,000bp

adcB

yceC

cwlK

1 27 306

yceE

yceF

yceG

yceH

yceI

yceB

opuAA

yceJ

opuAB

opuAC

yceK

80

ycgA

ycgB

amyE

340,000bp

ldh

lctP

ycgE

amhX

303

ycgF

ycgG

mdr

138

268

ycgI

nadE

aroK

ycgH

tmrB

ycgK

cah

ycgL

ycgM

ycgN

ycgO

ycgP

ycgJ

101

GeF-seq

ChAP-seq

ChAP-chip

569

yceD

330,000bp

360,000bp

370,000bp

ycgT

ycgQ

ycgR

nasA

ycgS

nasF

nasE nasD

nasC

folEB

yciB

yciC yczL

nasB

yckC

yckA

yckD

380,000bp

bglC

hxlR

yckB

nin

nucA

tlpC

hxlB

390,000bp

srfAA

srfAB

comS

srfAC

hxlA

GeF-seq

ChAP-seq

ChAP-chip

83

85 326 386

410,000bp

srfAC

srfAD

ycxA

420,000bp

ycxD

ycxB

ubiX

sfp sfp

ycxC

yczE

tcyC

tcyB

187

yclA

yclE

yclG

gerKA

dtpT

gerKC

gerKB

yclJ

yczF

yclH

yclK

rapC

440,000bp

phrC

yclN

yclO

yclP

yczN yczM yclM

yclI

yclQ

yczG

ycnB

ycnC

ycnD

ycnE

gabT

gabD

glcU

gdh

ycnL

gabR

ycnI

ycnJ

ycnK

635

GeF-seq

ChAP-seq

ChAP-chip

509

tcyA

yclD bsdD

ubiD

430,000bp

460,000bp

mtlA

mtlF

mtlD

ycsA

sipU

ycsD

yczH

ycsE

ycsF

ycsG

ycsI

kipI

470,000bp

kipA

kipR

lipC

yczI

yczO

ChAP-chip ChAP-seq

ycsN

mtlR

ydaB

yczJ

68

GeF-seq

pbpC

480,000bp

ydaD

ydaC

223

678 498

ydaE

ydaF

ydaG

ydaH

lrpC

topB

ydaJ

490,000bp

ydaK

ydaL

ydaM

ydaN

ydaO

mutT

ydaP

ydbA

ydzA

ydzK mntH

623

264

275

123 468

377

676

ydaS ydaT

gsiB

ydbB ydbC

dctS

ydbD

dctB

dctR

mtlA

510,000bp

520,000bp

530,000bp

ndoA dctR

dctP

ydbI

ydbJ

ydbK

ydbL

ydbM

ydbO

ydbN

ddl

murF

cshA

ydbS

ydbT

acpS

ydbP

ydcC

alrA

endB

ydcG rsbRA

rsbS rsbT

rsbU

rsbV rsbW

sigB

rsbX

ydcF

ydcH

ydcI

ydzL sacV ydcO

ydcK

ydcA

ydcL

626

501

175

320

immA

yddA ydcP

ydcQ

ydcR

ydcS ydcT

yddD yddC

yddB

yddE

yddF yddG

yddH

yddI

immR

yddJ

yddM phrI

rapI

yddK

660

467

340 131

530 686

381

GeF-seq

ChAP-seq

ChAP-chip

240

540,000bp

560,000bp

lrpA

yddQ

yddN

yddR

yddT ydzM

yddS

ydzN

ydeA

570,000bp

cspC

ydeD

lrpB

ydeB

401

279

692

633

ydzE ydeC

ydeG

ydeH

ydeI

ydeE

ydeL

ydeJ

253

ydeK

288 558

324

ydeM

ydeO

ydeN

ydeQ

ydzF

ydeS

ydeP

ydzO

590,000bp

ydzS ydzS ydfB

aseR ydfA

ydeR

ydfD

ydfF

ydfC

ydfE

ydfH

ydfG

ydfI

ydfJ

ydfN

ydzQ ydzP

nap

ydfK

ydfL

ydfO

ydfP

ydfQ

ydfM

ydzH

ydzR

474

GeF-seq

ChAP-seq

ChAP-chip

147

ydeF

580,000bp

610,000bp

ydfS

ydzR ydfR

ydgC

cotP

ydgD

ydgE

ydgB ydgA

ydgG

vmlR

ydgF

620,000bp

ydgH

ydgK

dinB

ydgI

ydgJ

ydhD

ydhE

ydhG

ydhB

ydhF

phoB

ydhJ

ydhH

ydhK

gmuB gmuA gmuC

ydhI

gmuD

640,000bp

gmuR

gmuE

gmuF

gmuG

thiL

pbuE

ydhU

645

ydiB

ydiC

rimI

gcp

moaC

ydhU

rex

tatCY tatAY

groES

ydiL ydiK

ydiF

579

634

GeF-seq

ChAP-seq

ChAP-chip

588 681

ydhC

630,000bp

660,000bp

groEL groES

ydiM

ydzV ydzU

ydiO

ydiP

ydiR

ydzT ydzT ydzT ydzT ydzT

ydzW ydzW ydzW

41

ydiS

ydjA

ydjB

ydzW ydzW ydzW ydzW

473

ydjC

gutB

gutP

ydjE

680,000bp

pspA

ydjG

ydjH

ydjI

gutR

44

516

iolT

ydjM

ydjJ

10

690,000bp

ydjN

yeaB

bdhA

202

ydzJ ydjO ydjP

559

yeaA

cotA

gabP

yeaC

yeaD

yebA

guaA

pbuG

yebC

yebD yebE

yebG

purE

purK

ydzX

162

335 624

318

611

GeF-seq

ChAP-seq

ChAP-chip

391 102

670,000bp

710,000bp

purK

purB

purC

purQ purS

purL

purF

purM

purN

purH

720,000bp

purD

yecA

yezC

GeF-seq

ChAP-seq

ChAP-chip

389

350

yerA

yezF

yerB

yerC

pcrB

pcrA

730,000bp

ligA

yerH

yerI

yerD

gatC gatA

sapB

551

308

12

opuE

740,000bp

gatB

swrC

yerO

dagK

yefA

yefC

yeeA

yeeB

yeeC

yefB

yeeG

yeeD yezA

8

204

465

yezG

yeeF

760,000bp

yeeG

rapH

phrH yeeI

yeeK

yezE

yesE

cotJB cotJA cotJC

yesF

770,000bp

780,000bp

790,000bp

yetJ yesJ

yesK

yesL

yesM

yesN

yesO

yesP

yesQ

yesR

yesS

rhgT

yesU

yesV

yesW

yesX

yesY

yesZ

yetA

lplA

lplB

lplC

lplD

yetF

yetI

yetG

270

yezD

yetK

yetM

yetH

yetO

yetL

91

ltaSA

yfnH

yfnG

yetN

444

GeF-seq

ChAP-seq

ChAP-chip

183

yetI

810,000bp

yfnG

yfnF

yfnE

yfnD

yfmT

yfnC

yfnB

yfmS

820,000bp

yfmR

yfmQ

yfmP

yfmO

yfmN

yfnA

yfmL

830,000bp

yfmK

yfmM

yflT yfmA

yfmG

yfmJ

yfmI

yfmF

yfmD

yfmC

yflS

citS

citT

yflP

citM

yflN

nosA

yflK

yfmB

yflH yflJ yflI

yflL

124

yflB yflD

nagP

mapB

yflA

yflE

93

yfkR yfkS

yfkT

379

158

348

yfkQ

235

GeF-seq

ChAP-seq

ChAP-chip

152

yfmE

pel

840,000bp

860,000bp

870,000bp

880,000bp

890,000bp

pdaA treP

treA

treR

yfkO

yfkQ

yfkM

yfkN

yfkJ

yfkL

yfkI yfkH

yfkE

yfkK

yfkD

yfjT

yfkF

yfkC

yfjP

yfkA

yfjR

yfzA

dusC

yfjM

yfjL

acoA

acoB

acoC

acoL

acoR

sspH

yfjQ

yfjF yfjE

675

360

86 448

609

malA

yfjD

yfjC

yfjB

malR

malP

malQ

yfiC

catD

catE

yfiF

yfjA

376

317

GeF-seq

ChAP-seq

ChAP-chip

428

yfjO

910,000bp

yfiG

yfiH

yfiI

yfiJ

yfiK

yfiL

yfiM

yfiN

estB

920,000bp

yfiQ

yfiT

padR

yfiS

yfiU

yfiZ

yfiV

yfhA

yfhB

yfhC

recX

yfhH

yfhI

yfhJ

yfhE yfhD yfhF

yfiY

422

yfhK

yfhL yfhM

940,000bp

csbB

yfhO

yfhQ

sspK

yfhP

fabL

sspE ygaB

ygaC

ygaD

ygaF

yfhS

ygaE

546

gsaB

perR

ygxA

ygzB

543

439

GeF-seq

ChAP-seq

ChAP-chip

480

yfiR

mprF

930,000bp

960,000bp

ygzA

spo0M

ygaJ

thiC

senS

ygzC

ygaK

GeF-seq

ChAP-seq

ChAP-chip

524

970,000bp

ssuB

ssuA

ssuC

ssuD

ygaN

katA

174

rpsNB

ygaO

532

trnSL-Gly1

ygzD

yhbA

yhbB

cspR

980,000bp

yhbD

yhbE

yhbF

prkA

yhbH

yhbI

yhbJ

yhcA

yhcB

yhcE yhcC yhcD

990,000bp

yhcF yhcG

yhcH

yhcI

yhcJ

yhzB

cspB

20

652

tcyP

yhcK

yhcN

yhcM

yhcO

yhcR

yhcQ

yhcS

yhcU

yhcT

yhcV

yhcW

yhcX

1,010,000bp

yhzG yhxA

glpP

glpF

glpK

glpD

pgcA

yhcY

yhcZ

1,020,000bp

yhdA

yhdC

spoVR

1,030,000bp

lytE

citA

yhdF

ctrA

yhdH

yhdJ

1,040,000bp

yhdN

plsC

yhdR

yhdY yhdX

yhdT

yhdL yhdB

lytF

nsrR

ygxB

phoA

356 265

yhdI

yheI yheJ

dat

yheH

yhdV

yhdK

sigM

yhdP

cueR

crcBA

yhdW

yheN

nhaC

nhaX

yheG

433

yheF

529

GeF-seq

ChAP-seq

ChAP-chip

243 550

citR

yhdZ

1,060,000bp

yheB

sspB

yheE yheD

yheA

yheC

yhaX

1,070,000bp

hemZ

yhaR

yhaZ

yhaU

khtT

natA

khtS

natB

yhaO

yhaN

yhaM

yhaL

yhzD

yhzE

yhaI

prsA

67

yhaJ

605

yhzF

scoC

yhaH

ecsA

trpP

serC

ecsB

1,090,000bp

ecsC

pbpF

hinT

yhaA

606

yhfA

hemE

hemH

hemY

yhgD

yhgE

yhfC

yhgB yhgC

yhfE

yhfF

fabHB

yhfI

gltT

429

yhfJ

yhfH

74

GeF-seq

ChAP-seq

ChAP-chip

436

1,080,000bp

1,110,000bp

yhfJ

yhfK

lcfB

yhfN

yhfO

yhfM

yhfP

1,120,000bp

yhfQ

yhxC

aprE

phoE

yhfS

yhfT

bioY

hemAT

comK

yhfW

yhzC

1,130,000bp

yhjA

yhxD

yhjE

yhjB

yhjC

sipV

yhjG

yhjH

yhjD

1,140,000bp

yhjM

glcP

207

ntdB

ntdA

421

yhjN

636 121

601

addB

yhjO

yhjQ

addA

sbcD

sbcC

yisB

gerPE gerPC gerPF gerPD

yhjR

646

GeF-seq

ChAP-seq

ChAP-chip

455

ntdC

yhjP

1,160,000bp

yisK

gerPA gerPB

wprA

asnO

yisI yisJ

yisP

yisN

yizA

yisR

degA

yisS

yisQ

yisV

yisT

249

1,180,000bp

yisY

yisU

yisX

yitC

yisZ

yitA

1,190,000bp

yitD

yitB

yitL

yitE

yitF

yitG

yitH

yitI

yitJ

yitK

572

yizB yitQ

yitM

yitO

yitR

nprB

yitT

yitP

yitS

48 366 603 682 66

246

ipi

yitV

yizC

yitW

yitY

yitZ

argC

argJ

argB

argD

carA

yitU

15

595

GeF-seq

ChAP-seq

ChAP-chip

4

yisL

1,170,000bp

1,210,000bp

carA

carB

argF

yjzC

yjaU

yjaV

med

comZ

yjzD

GeF-seq

ChAP-seq

ChAP-chip

221

fabHA

fabF

1,220,000bp

yjaZ

appD

yjzB

192

142

appF

appA

appA

appB

appC

yjbA

oppA

trpS

230

493

347

1,230,000bp

oppB

oppC

oppD

oppF

yjbB

yjbC

spxA

mecA

yjbE

coiA

1,240,000bp

pepF

yjbL

yizD

563

yjbH

662

yjbI

yjbJ

yjbK

yjbM

ppnKA

yjbO

yjbQ

prpE

tenA

tenI

thiO

thiG thiS

thiF

thiD

fabI

cotO

cotZ

gerPB

1,260,000bp

1,270,000bp

yjcZ yjcA

cotY

cotX

yjzK

spoVIF

cotW cotV

yjzE

yjcD

metI

yjcF

yjcG

metC

trnSL-Val2

yjcH

yjcK

yjcL

yjcN

yjzG yjzF yjcO

yjcP

yjcQ

yjcR

yjcS

yjdA

1,280,000bp

manR

yjcM

manP

manA

yjdF

yjdB

yjdI

yjdG

165

yjdH

yjeA

yjzH yjdJ

ctaO

489

yjfC

cotT

yjfA

yjgC

yjfB

yjgA

yjgD

yjhA

yjgB

yjiB

yjiC

yjjA

yjiA

677 37 22

284

yjhB

yjzI

316

yjlB

yjkA

yjkB

rex

ndh

yjlA

92 90

582

GeF-seq

ChAP-seq

ChAP-chip

407

1,290,000bp

1,310,000bp

ndh

uxaC

exuM

yjmC

yjmD

uxuA

uxuB

exuT

exuR

1,320,000bp

uxaB

uxaA

yjoB

yjnA

323

phrA

yjoA

xlyB

yjqB

yjpA

334

xkdB yjzJ

yjqC

yjqA

xkdA

568

xkdD ykzK xtrA xpf

xkdC

xtmA

xtmB

xkdE

xkdF

1,340,000bp

xkdG

ykzL xkdH xkdI

xkdJ

xkdK ykzM

xkdM

xkdN

xkdO xkzB

xkdP

xkdQ

xkdR xkdS

xkdT

xkdV xkzA

xkdU

xepA xkdW xkdX

xhlB xhlA xlyA

spoIISA spoIISB

xre

394

254

pit

412

GeF-seq

ChAP-seq

ChAP-chip

440

rapA

1,330,000bp

1,360,000bp

mhqA

pit

ykaA

ykcB

ykcC

proG

ykbA

1,370,000bp

dppA

dppB

dppC

dppD

dppE

ykfA

ykfB

ykfC

ykfD

ykhA

htrA

ykgB

hmp

ykjA

ykgA

ykkA

ykkB

ykkC ykkD purU

proB

1,390,000bp

proA

ohrA

ykzH

ohrB

ykzN

ohrR

594

657

guaD

rsbRB

metE

ispA

688

ykoG

thiX

thiW

thiV

ykoH

ykoI

ykoJ

ykzD

thiU

ykoL ykzB ykoM

mgtE

ykzO

tnrA

ykoN

52 209

244

GeF-seq

ChAP-seq

ChAP-chip

17

1,380,000bp

1,410,000bp

ykoP

ykoN

ykoS

ykoT

ykoQ

ykoX

ykoU

ykoV

1,420,000bp

ykoY

sigI

rsgI

ykoW

ykzE ykzP

ktrD

sspD ykrK

415

kinE

ogt

mtnE

ykrP

mtnA

mtnK

454

mtnW

mtnX

mtnB

mtnU

1,440,000bp

eag spo0E

mtnD

ykvA

604

mhqR

kinD

390

ykvI

motB

motA

261

queC

queD

queE

queF

ykvO

clpE

ykvP

ykzQ ykvQ

ykzR

ykvR

ykvN

500

ykzS

ykvT

ykvU

ykvS

33

139

395

255

295 190 443

GeF-seq

ChAP-seq

ChAP-chip

353

htpX

1,430,000bp

1,460,000bp

ykvU

stoA

zosA

ykvY

ykvZ

glcT

ptsG

ptsI ptsH

1,470,000bp

splA splB

mcpC

ykwB

ykwC

pbpH

ykwD

ChAP-chip ChAP-seq

kinA

cheV

patA

106

GeF-seq

1,480,000bp

ykzT

fadH

ykyB

ykuC

ykuD

1,490,000bp

fadG

ykzU

ykuH

ykuI

ykuJ ykuK

ykzF ykuL

ccpC

ykuN

ykuO

ykuP

dapH

dapL

ykuE

ykuS

ykuU

ykuV

rok

ykuT

549

598 191

14

mobA

moeB

moeA

mobB

moaE

yknT

94 481

72

285

673

moaD

yknU

1,510,000bp

yknU

yknV

yknW

yknX

yknY

yknZ

fruR

fruK

1,520,000bp

fruA

sipT

ykpA

panE

abh

ykoA

ykqA

ktrC

adeC

ykrA

mreBH ykpC

ampS

668

566

ykyA

pdhA

1,540,000bp

pdhB

pdhC

pdhD

ykzW

yktA

ykzI suhB

ykzC

ylaC ylaB

ylaA

ylaD

bipA

ylaH

ylaK

ylaJ rnjA

ykzG

defB

ykzV

197

slp

speA

111

yktB

yktD

73

nprE

658

ylaE

491

ylaF

571

ylaI

39

GeF-seq

ChAP-seq

ChAP-chip

21

kinC

1,530,000bp

1,560,000bp

ylaK

glsB

ylaN

ftsW

pycA

ctaB

ylaL

1,570,000bp

ctaC

ctaD

ctaE

ctaF ctaG

ylbB

ctaA

ylbD

ylbE ylbF

ylbG

ylbH

coaD

ylbA

556 115

615

ylbK

ylbL

ylbJ

ylbN

ylbM

rpmF ylbO

ylzH

ylbQ

yllA

1,590,000bp

mraZ

mraW

ftsL pbpB

spoVD

murE

mraY

murD

spoVE

murG

murB

divIB

ylxW

ylxX

sbp

ftsA

ftsZ

bpr

ylbP

179

580

57 486

205

378

GeF-seq

ChAP-seq

ChAP-chip

305

ylbC

1,580,000bp

1,610,000bp

bpr

spoIIGA

sigE

sigG

ylmA

thiQ

ylmC

ylmD

ylmE

1,620,000bp

sepF

ylmG ylmH

divIVA

ileS

ylyA

lspA

rluD

pyrR

pyrP

1,630,000bp

pyrB

pyrC

pyrAA

pyrAB

pyrK

pyrD

pyrF

pyrE

1,640,000bp

cysH

cysP

sat

cysC

sumT

sirB

sirC

yloB

gmk ylzA

yloC

coaBC rpoZ

priA

defA

fmt

rsmB

yloN

yloA

273

644

GeF-seq

ChAP-seq

ChAP-chip

157

1,660,000bp

yloN

prpC

prkC

cpgA

rpe

thiN

spoVM

yloU yloV

sdaAB

sdaAA

1,670,000bp

recG

fapR

plsX

fabD

fabG

acpA rnc

smc

1,680,000bp

ftsY

ylqC rpsP ylqD rimM

ylxM ffh

rpmB

trmD

rplS

rbgA

rnhB

ylqG

ylqH

1,690,000bp

sucC

sucD

dprA

topA

trmFO

codV

clpQ

clpY

codY

flgB flgC

fliE fliF

fliG

fliH

fliI

fliJ

ylxF

fliK

flgD

ylqB

96

219

GeF-seq

ChAP-seq

ChAP-chip

650

1,710,000bp

flgD

flgE

fliL ylzI

GeF-seq

ChAP-seq

ChAP-chip

321

1,720,000bp

1,730,000bp

1,740,000bp

fliR fliM

fliY

cheY fliZ

684

fliP

fliQ

flhB

flhA

flhF

ylxH

cheB

cheA

cheW

cheC

cheD

sigD

ylxL

rpsB

tsf

pyrH

476 400

frr

uppS

517

cdsA

dxr

rseP

proS

polC

ylxS

nusA

ylxR

rplGA infB

ylxP rbfA

339

truB

ribC

rpsO

pnpA

ylxY

570

mlpA

ymxH

spoVFA

spoVFB

asd

dapG

dapA

rnjB

1,760,000bp

rnjB

tepA

ylzJ spoIIIE

ymfC

ymfD

ymfF

ymfH

ymfI

1,770,000bp

ymfJ ymfK

ymfK

ymfM

pgsA

cinA

recA

pbpX

ymdA

ymdB

spoVS

1,780,000bp

tdh

kbl

ymcB

ymcA

cotE

mutS

1,790,000bp

mutL

pksA

ymzD

302

117

531

pksC

pksD

pksG

pksH

pksI

pksJ

ymcC

217 25 319

562

pksF acpK

pksE

622 482

229

GeF-seq

ChAP-seq

ChAP-chip

336

pksB

1,810,000bp

pksJ

1,820,000bp

1,830,000bp

pksL

1,840,000bp

pksM

pksN

GeF-seq

ChAP-seq

ChAP-chip

484

1,860,000bp

pksN

1,870,000bp

ymzE ymzE

pksR

pksS

ymzB

ymaE

ymaC

ymaD

aprX

ymaF

ebrB ebrA

ymaH

ymzC ymzA

nrdI nrdE

nrdF

ymaB

ymaG

spoVK

ynbA

ynbB

glnR

glnA

ynxB

1,890,000bp

ynzF

ynzG

ynaB

ynaC

ynaD

ynaE

ynaF ynaG

ynzI ynaI

xynP

xynB

xylA

cwlC

xylB

yncC

xylR

43

290 654 135

34

696

385

yncE

yncB

alrB

186

294

GeF-seq

ChAP-seq

ChAP-chip

241

miaA

1,880,000bp

1,910,000bp

yncE

yncF

ynzJ

thyA

cotU

yndA

yncM

262

cotC tatAC

yndD

yndE

yndF

yndG

yndH

yndJ

yndK

yndL

yndB

fosB

yndM

351

208

597

yneA yneB

ynzC

1,930,000bp

tkt

yneE

lexA

yneF

ccdA

ynzD

194

247

yneI

yneJ

citB

yneK

423

cotM

yneN

sspN ynzL tlp

1,940,000bp

yneP yneQ

sspO sspP

yneT

yneR plsY

69

parE

parC

alsT

eglS

ynfE

ynfC

576

yngA

xynC

694

278

xynD

169

yngB

yngC

yngD

yngE

dacC

yoxA

76

GeF-seq

ChAP-seq

ChAP-chip

621

ynzK

ynzB

1,920,000bp

1,960,000bp

yngE

yngF

yngG

yngHA yngHB

yngI

yngJ

ynzE

yngK

GeF-seq

ChAP-seq

ChAP-chip

293

yngL

ppsE

1,970,000bp

1,980,000bp

ppsD

ppsC

119

1,990,000bp

ppsB

300

ppsA

460

210

2,010,000bp

iseA

yoxA

ggt

yoeC trnSL-Arg1

yoeA

2,020,000bp

yogA

yoeD

gltC

ftsR

gltB

yoxC yoxB

gltA

proJ

proH

rtp

2,030,000bp

yoaA

yoaE

yoxD

yoaB

yoaC

yozQ

yoaD

yoaG

yoaI

pelB

yoaH

exlX

yoaM

yoaQ

yoaK

yozS

yoaN

yoaO

yoaP

yoaS

yozT yozF

yozG yoaT

cyeA

yoaR

penP

yoaU

452 461

yoaW

yoaZ

yobA

419

327

GeF-seq

ChAP-seq

ChAP-chip

426 699 159

yoaF

2,040,000bp

2,060,000bp

2,070,000bp

2,080,000bp

2,090,000bp

rapK yobB

yobA yozU

yobD

pps

xynA

yozV

yozI

yobE

yozX

yozH

613 227

yobF

yozW

yozY

yozZ

phrK

yozJ

yozM

yobH

297

yobI

yoyA

399

yobJ

651

250

yobK

yobL

yobO

yobW

yobM

csaA

667

602

yobQ

yobR

yobS

yobT

yobU

yocA

yobV

yocC

czrA

yozB

683

yocD

des

desK

desR

yocB

yocH

434

yocN yozN

yoyB

yocI

yocJ

yocK

536

yocL

yocM

511

yozO

505

GeF-seq

ChAP-seq

ChAP-chip

282

514 89 136

yozK yozL

yobN

2,110,000bp

dhaS

sqhC

sodF

yozC

2,120,000bp

yocS

yocR

odhB

odhA

yojO

yojN

sodC

cwlS

425

yojK

rsbRC

yojJ

gerT

yojG

56

yojF yoyC yojE

yodA

yojB yojA

yodF yoyD

yodC

yodB

2,140,000bp

yodD

yodH

yodE

yodI

ctpA

614

yoyE

yodJ

642

deoD

yoyF

yodL yodM

yozD

yodN

cgeA

kamA yozE yokU

yodP

yodQ

yodR

yodS

cgeE yoyG

yodT

cgeD

50

cgeB

cgeC

269

GeF-seq

ChAP-seq

ChAP-chip

354

norM

2,130,000bp

2,160,000bp

cgeB

ypqP

yotL

yotM yotN

phy

sspC

yotD yotJ yotG yotE yotB yotK yotI yotH yotF yotC

yosU

yosX

307

yosW

yosV yojW

2,180,000bp

2,190,000bp

yosA

yosT

yosS

yosP yosR

yosQ

nrdEB

nrdIB yosL

yosJ yosH yosK yosI

yosG

yosE yosF yosD

yosC

yosB

yorZ

yoqW

yorY yorW mtbP yorX yorV

yorS yorT

560

yorR

yorP yorN yorQ yorO yorM

441

yorL

yorK

yorJ

yorI

113

yorH

yorG

yorF

yorE

35

yorD

yorC

yorB yorA

yoqZ

yoqY

ligB

yoqX

yoqT

yoqU

yoqO

yoqS yoqR yoqP

yoqM

yoqN

yoqL

64 502 679

310

yoqJ yoqK

yoqH yoqI

yoqE yoqG yoqF yoqD

410

GeF-seq

ChAP-seq

ChAP-chip

330

2,170,000bp

2,210,000bp

2,220,000bp

yoyI yoyH

yopS

yoqD

yoqC

yopY yoqB yoqA yopZ yopX

yopW

yopT yopV yopU

yopR

yopQ

yopP

yopN yopO yopM

yopK yopL

yopJ

yopI

yopH

yopF yopG yopE

ChAP-seq

ChAP-chip

296

GeF-seq

2,230,000bp

yopD

yonO yonP

yopC

yopB

98 103

yopA

172 417

yonX

yonV

yoyJ yonU yonT

yonS

yonJ yonK

yonN

yonR

yonH

yonG

2,240,000bp

yonF

yonE

yonD

yonC

yonB

yonA

yomX yomZ yomY

yomW

yomV

yomU

youA

yomT yomS yomR

yomO yomQ yomP

yonI

188

71

yomN

yomM

yomK

yozP

349

yomL

yomJ

youB

380

496

134

yomI

2,260,000bp

yomI

yomH

yomG

yomF

2,270,000bp

yomE

yomD

bhlB bhlA

blyA

yoyK yoyK

yolC

bdbB

yolJ

bdbA

sunT

sunA

199

sunI

uvrX

yolD

yolB yolA

233

607

yokL

189

yokK

yokJ

yokI

yokH

yokF

2,290,000bp

yokE

yokD

yokA

yokG

yokC

373

ypqP

ypoP

yokB

280

msrB

228

yplP

msrA

ypmS ypmT

dinF

ypmR

scuA

yplQ

ypmP ilvA

ypkP

168

dfrA

thyB

ypjQ

ypjP

ypiP

499

GeF-seq

ChAP-seq

ChAP-chip

523

2,280,000bp

2,310,000bp

metA

ypiP

yphP

ilvD

ypgR

ypgQ

ugtP

cspD

bsaA

ypzA

ypdP

2,320,000bp

ypdQ

sspL

ypeP ypeQ

degR

kduI

ypbS ypzF ypbR

exoA

ypbQ

bcsA

pbuX

xpt

ypwA

kdgT

kdgA

kdgK

kduD

ypzG

kdgR

ypvA

312 405

671

2,340,000bp

yptA

ypqA

ypsC

gpsB ypsA

cotD

yprB

yprA

ypqE

yppF

yppG

sspM

yppE

yppD

recU

ponA

yppC

ypoC

nth

dnaD

asnS

aspB

ypmB

226

ypmA dinG

333

617

GeF-seq

ChAP-seq

ChAP-chip

176

2,330,000bp

2,360,000bp

2,370,000bp

2,380,000bp

2,390,000bp

ypjC

dinG

panD panC

panB

birA

cca

ypjH

ypjG

mgsA

dapB

ypzI

ypjD

ypjB

ypjA

qcrC

qcrB

qcrA

ypiF

267 148

ypiA

aroE

tyrA

432

hisC

trpA

trpB

trpF

trpC

trpD

trpE

aroH aroB

aroF

cheR

ndk

hepT

menH

547

hepS

folEA mtrB

215

hbs

spoIVA

yphF

yphE

643

gpsA

seaA ypzH

engA

81

yphA

fni

ypfD

ypfA ypfB

cmk

ypeB

sleB

206

GeF-seq

ChAP-seq

ChAP-chip

590

ypiB

2,410,000bp

2,420,000bp

fer

sleB

prsW

ypdA

gudB

mecB

ypbF

ypbE

ypbD

recQ

ypbB

serA

fmnP

ypuF

ypzE

218 398

424

2,440,000bp

aroC

344

rsiX

sigX

resE

resD

resC

resB

resA

rluB

spmB

spmA

dacB

ypuI

spcB

scpA

ypzC

ypzK

ribH

ribAB

ribE

ribD

ypuD

sipS

ypzD

ypuC ypzJ ypuC ypuB

663

ypuA

ppiB

lysA

24

163

spoVAF

spoVAEA

spoVAD spoVAEB

spoVAA spoVAC spoVAB

445

sigF

spoIIAA spoIIAB dacF

fur pupG

299 5

drm

55

ripX

yqzK

655

GeF-seq

ChAP-seq

ChAP-chip

116

ypbG

2,430,000bp

2,460,000bp

ansR

fur

spoIIM

yqkK mleA

mleN

ansB

GeF-seq

ChAP-seq

ChAP-chip

581

ansA

yqkF

yqxK

nudF

533

2,470,000bp

yqkD

yqkE

yqzH

yqkB yqkC yqkA

yqjZ yqjY

yqjX polYB

yqjV

2,480,000bp

yqjU

yqjT coaA

proI

dsdA

yqjQ

yqjP

yqjM

yqjN

yqjL

2,490,000bp

zwf

rnz

yqzJ oxaAB

gndA

polYA

yqjF

bmrU

yqjE

yqjD

yqjC

yqjB

yqjA

artR

608

artQ

artP

88

yqiW

bmr

bmrR

bkdB

bkdAB

bkdAA

2,510,000bp

2,520,000bp

yqzF

bkdAA

lpdV

buk

bcd

ptb

bkdR

2,530,000bp

2,540,000bp

yqiG

prpB

prpD

prpC

mmgC

mmgB

mmgA

yqiK

yqiI

yqhQ

yqiH

spo0A

spoIVB

ahrC

yqxC

16

dxs

xseA xseB

ispA

folD

nusB

128

yqhY

accC

accB

spoIIIAH spoIIIAG

spoIIIAC spoIIIAA spoIIIAD spoIIIAB

spoIIIAF spoIIIAE

yqhV

efp

yqhT

yqhS

yqhR

yqhL

yqhO

586

mntR

371

yqhM

yqhH

gcvPB

gcvPA

gcvT

239

GeF-seq

ChAP-seq

ChAP-chip

630

recN

yqhP

2,560,000bp

yqhH

sinR sinI

yqhG

yqzG

tasA

sipW

yqhB

comGG comGD comGB yqzE comGF comGE comGC

yqxM

331

comGA

trnSL-Gln1 yqgY

yqxL

rsbRD

mgsR

2,580,000bp

yqgW

yqgX

yqzD yqzC

yqgV yqgU

78 411

2,590,000bp

yqgT

362

yqgS

glcK

181

yqgN yqgO

yqgQ glpG

392

yqgM rpmGA

yqgL

yqgB

pstBB

pstBA

pstA

pstC

pstS

pbpA

yqgE

sodA

648

yqfZ

yqgC

ispG

yqfW

yqgA

yqfT

yqfX

zur

yqfU

yqfQ

nfo

ispH

cshB

yqfO

680

trmK

cccA

453

248

GeF-seq

ChAP-seq

ChAP-chip

632

2,570,000bp

2,610,000bp

2,620,000bp

2,630,000bp

antE

2,640,000bp

yqeW

rpsT

yqzM

comER

sda

yqeD

aroD sigA

dnaG

yqxD

yqfL

ccpN

glyS

glyQ

recO

yqzL era

cdd

237 252

yqfF

phoH

yqfD

yqfC yqfB

yqfA

yqeZ

yqeY

232

rpsU

rimO

rsmE

prmA

690

dnaJ

dnaK

grpE

hrcA

hemN

lepA

yqxA spoIIP

gpr

holA

comEC

542

comEB

comEA

yqeM

yqeL yqeK

nadD

yqeI

yqeH

446

yqeG

552

yqeF

120 574

cwlH

369

GeF-seq

ChAP-seq

ChAP-chip

367

dgkA yqfG

2,660,000bp

yqeD

yqeB

spoIVCB

yqeC

nucB

yqzI phrE

rapE

spoIVCA

arsC

yqcK

arsR

yqcG

yqcF

yqcI

478

2,690,000bp

yqdB

yqxJ yqxI

670

2,680,000bp

cwlA

yqxH

yqxG

yqcD yqcE yqcC

yqcA yqcB

yqbT

yqbS

yqbQ yqbR

yqbP

yqbN yqbN

yqbO

512 256

11

yqaP

yqbM

yqbJ yqzN

yqbK

yqaE

yqaN yqbI

yqbH yqbG

yqbF yqbE

yqbD

yqbC

yqbB

yqbA

yqaT

yqaS

554

yqaR

yqaQ

418

yqaO

yqaM yqzO

yqaL

yqaK

yqaG yqaI yqaH

yqaJ

yqaF yqdA

yqaD

224 286

375

GeF-seq

ChAP-seq

ChAP-chip

304

arsB

2,670,000bp

2,710,000bp

yqaB

spoIIIC

yqaC

yrkS

ChAP-seq

ChAP-chip

332

GeF-seq

yrkO

psiE

200

yrkQ

yrkP

2,720,000bp

yrkN

blt

yrkL

155

yrkK

463 628 140

yrkJ

yrkH yrkI

yrkF

yrkE

yrzM yrkD yrzN yrkC

yrkB bltR

610

2,730,000bp

bltD

yrdQ

yrkA

yrdR yrzO

2,740,000bp

gltR

yrdP

czcD

brnQ yrdK

yrdN

540

yrpB

6

azlD azlC

azlB

yrdF

cypA

yrdD yrdC yrdD yrdD

yrdB

313

yrdA

63

450

yrpC

yrpD

aadK

yrpG

yrpE

495

sigZ

yraM

yraO

yraN

yraL

yraK

csn

575

649

2,760,000bp

yraF yraG

yraK

yraJ

yraI

yraD yraE

adhB

yrzP adhA

yraH

yraA

yraB

aapA

sacC

462

levG

levF

levE

levD

yrhO

levR

sigV

2,780,000bp

rsiV

oatA

yrhK

yrhP

456

2,790,000bp

yrhE

cypB

bscR

112

yrhH

528

yrzI

539

yrhG

yrhD

yrzA

yrhF

yrhC mccB

45

689

mccA

mtnN

yrrT

yrrS

pbpI

greA

udk

yrrO

167

yrrN

yrrM

yrrL

yrzB yrrK

yrzL alaS

182

GeF-seq

ChAP-seq

ChAP-chip

337

2,770,000bp

2,810,000bp

glnQ

alaS

glnH

glnM

2,820,000bp

glnP

yrvN

yrzR yrzQ yrrD

yrrI

yrrC

yrrB

trmU

iscS

2,830,000bp

yrvJ

cymR

yrvM

aspS

hisS

spoVB

yrzK

dtd

relA

apt

recJ

yrvD

36

yrvC

secDF

150

yrzE

comN

yrbG

yrzT yrzH yrbD

yrzF

yrbF tgt

ruvB yrzS

queA

ruvA

bofC

csbX

nifS

yrbE

yrbC

132

372

coxA

safA

nadA

513

nadC

nadB

171

GeF-seq

ChAP-seq

ChAP-chip

470

2,840,000bp

2,860,000bp

nifS

2,870,000bp

nadR

2,880,000bp

yszA

2,890,000bp

ysxD

ysnD

ysnE

ysnF

ysxB pheA

yszB

obg

spo0B

rpmA

rplU

spoIVFB

spoIVFA

minD

minC

mreD

mreB

radC

maf

spoIIB

comC

folC

valS

ysxE

spoVID

hemL

hemB

hemD

hemC

hemX

hemA

ysxC

631

lonA

lonB

clpX

361

tig

ysoA

leuD

leuC

leuB

leuA

ilvC

ilvH

ilvB

266

GeF-seq

ChAP-seq

ChAP-chip

346

mreC

2,910,000bp

2,920,000bp

2,930,000bp

2,940,000bp

ysfB yslB

ysnB

ysnA

rph

gerM

racE

ysmB

gerE ysmA

sdhB

sdhA

sdhC

rnhC

lysC

uvrC

trxA

xsa

etfA

etfB

fadB

fadR

lcfA

yshE

mutSB

polX

309

yshA

pheT

pheS

glcD

glcF

ysgA

ysfE

cstA

277

abfA

araQ

araP

araN

araM

araL

araD

araB

araA

abnA

693

GeF-seq

ChAP-seq

ChAP-chip

521

yshB

sspI

2,960,000bp

ysdB

abnA

ysdC

yscB

ysdA rplT

infC rpmI

ChAP-chip ChAP-seq GeF-seq

ysaA

lrgB

31

2,970,000bp

lrgA

lytT

lytS

ytbD

thrS

ytxC

ytxB

dnaI

564

dnaB

nrdR

speD

gapB

2,980,000bp

2,990,000bp

ytbE

ytcD

ytvI

coaE

637

ytaF

mutM

polA

phoR

phoP

mdh

icd

citZ

ytwI

ytrH ytrI

ytzA

pyk

pfkA

accA

accD

118

281

ytsJ

58

dnaE

ytzJ

nrnA

ytpI

ytoI

ytnM

ytnL

3,010,000bp

3,020,000bp

3,030,000bp

ytlI

ytnL

rbfK

ytnJ

ytnI ytmO

tcyN

tcyM

tcyL

tcyK

tcyJ

ppnKB

ytmI

ytkL

argH ytzD

argG

moaB

ackA

ytxK

tpx

ytfJ

ytfI

yteJ

sppA

braB

ytcJ

567

ytcI

sspA thiI

370

hisJ

iscS

ytsP

ezrA

rpsD

yttP

acuA

ytrP

acuB

acuC

acsA ytzK

tyrS

291

ytxE

ytxD

ccpA

aroA

ytxJ ytxH

146

ytxG

murC

ytpS

301

GeF-seq

ChAP-seq

ChAP-chip

368

ytkK

3,040,000bp

3,060,000bp

ytoQ

ytpS

ytpR

ytpQ

ytpP

ytzB

ytoP

3,070,000bp

ytzH

malS

ytnP

trmB

ytkP

ytmP

amyX

ytlR

ytlQ

3,080,000bp

pbuO

ytlP

ytzE

ytjP

ythQ

ythP

ytfP

ytzG

3,090,000bp

opuD

ytdP

yteU yteV

ytgP

yteT

yteS

yteR

msmR

yteP

ytcQ

ytcP

ytbQ

bioI

bioB

bioF

bioK

bioW

amyD

ytaP

109

477

GeF-seq

ChAP-seq

ChAP-chip

343

bioD

msmE

3,110,000bp

amyD

amyC

melA

ytvA

ytwF

leuS

ytvB

3,120,000bp

yttA

yttB

3,130,000bp

ytqA

bceB

bceA

bceS

bceR

ytrF

ytrE

ytrD

ytrB

ytrA

ytzC

ytoA

ytpB

ytpA

pckA

ytnA

asnB

ytlA

metK

ytlC

ytlD

ytmB ytmA

ytzI

ytkD

129 216

ytkC

dps

328

ytjA

ytkA

luxS

ythA

ytiB

ythB

ytzL

rpmEB

mntD

mntC

mntB

mntA

menC

menE

menB

ytxM

260

GeF-seq

ChAP-seq

ChAP-chip

526

ytrC

ytqB

3,140,000bp

3,160,000bp

yteA

ytcA

ytcB

3,170,000bp

ytcC

cotI

3,180,000bp

ytaB

3,190,000bp

thiT

yuaE

yuaC

yuaB

ktrA

ktrB

cdoA

yulF

uppP ytxM

menD

menF

ytdA

ytxO

cotS

cotSA

glgA

glgD

glgC

glgB

yuaI

18

yuaG

yuaF

yuaD

553

gbsB

gbsA

485

640

yubF lytG

464 145

669

84

yubD

691

yubA

374

yulE

yulD yulC

30

GeF-seq

ChAP-seq

ChAP-chip

13

glgP

3,210,000bp

3,220,000bp

tgl

yulC

yulB

yuxG

tlpB

mcpA

tlpA

mcpB

GeF-seq

ChAP-seq

ChAP-chip

107

3,230,000bp

mstX yugO

yuzH

yugU

yugT

yugS

180

yugP

75

yuzI

yuzA

yugN

203

yugM

pgi

yugK

yugJ

yugF

yugI

yugH

yugG

patB

yugE

kinB

3,240,000bp

kapB

yuxJ

pbpD

yuxK

kapD

yufL

yufK

593

yufM

yufN

yufO

yufP

yufQ

maeN

mrpA

yufS

mrpB

mrpC mrpD

3,260,000bp

mrpD

mrpG mrpF

mrpE

3,270,000bp

yuzC

yuxO

comA

comQ comX

comP

3,280,000bp

yuzE

yukF

ald

yukJ

yueF degQ

yuxH

pncB

pncA

yueI

yueH yueG

yuzF

yueE

yueD

yueC

yueB

yukB

dhbF ybdZ

yukD yukE

287 143 170

641

bioYB

dhbB

dhbE

dhbC

dhbA

besA

yuiH

653

yuiD

yuiF

pepA

yuiC

yuiB yuiA

198

GeF-seq

ChAP-seq

ChAP-chip

355

yukC

3,290,000bp

3,310,000bp

yumC

guaC

yumB

yutJ

yuzG

paiB

paiA

yutM

dapF

yutK

3,320,000bp

yutI

yuzB

yuzD

yutG

yuxL

thrB

thrC

hom

yutH

yutC

yutF

yutE

3,330,000bp

lytH

yutD

pucR

lipA

yunB

yunC yunD

yunE

yunF

yunG

3,340,000bp

pucJ

pucK

pucL

pucM

pucH

yuzJ

bsn

pucE

pucD

pucC

pucB

pucA

pucG

frlR

pucF

yurJ

frlM

frlN

frlO

156

GeF-seq

ChAP-seq

ChAP-chip

587

frlD

3,360,000bp

3,370,000bp

3,380,000bp

yurS sspG

yusN yuzM

yuzL

yusO

yusP

3,390,000bp

yusT

yusZ

mrgA

cssR

cssS

yuxN

gerAA

gerAB

gerAC

yusH frlO

frlB

yurQ

yurR

yurT

yuzN

sufB

iscU

sufS

sufD

sufC

yuzK yurZ

metN

metP

metQ

yusD

yusE yusF

yusG

yusI

fadE

fadA

fadN

fadM

yusQ

yusR

yusS

yusU yusV

yusW

yusY

yusY

htrB

yuzO

fumC

yvzF

liaR

342

42

liaF

liaG

liaH

liaI

627

yvqJ

665

GeF-seq

ChAP-seq

ChAP-chip

2

liaS

3,410,000bp

yvrD

yvqJ

yvqK

yvrA

yvrB

yvrC

yvrJ

yvrE

yvrG

yvrH

214 108

3,420,000bp

oxdC

yvrL

sigO rsoA

3,430,000bp

fhuD

yvsG

yvgJ

yvgL

yvgM

3,440,000bp

yvgO

yvaA

csoR yvrN

yvrO

yvrP

fhuC

fhuB

lysP

sspJ

yvgK

yvgN

nhaK

cysI

cysJ

137 77 616

231

helD

yvgT

bdbC

bdbD

copB

copA

copZ

yvaB

451

yvaC

213

yvaD

yvaE yvaF

yvaG

153

506

ChAP-seq

ChAP-chip

475

fhuG

GeF-seq

1421.495 pt

3,460,000bp

yvaM

yvaG

smpB

rnr

yvaK

GeF-seq

ChAP-seq

ChAP-chip

32 487

secG

rghRA rghRB

yvaP

yvzC

3,470,000bp

yvaQ

yvaV

opuBD

opuBC

opuBB

sdpA

sdpB

spbC

3,480,000bp

yvbF

opuBA

sdpI

sdpR

opuCD

opuCC

opuCB

opuCA

yvbH

yvbG

yvbI

3,490,000bp

yvbK

yvbJ

araR

eno

pgm

tpiA

pgk

gapA

cggR

araE

cyeB

yvbT

yvbU

rsbQ

yvbW

yvbX

yvbY

yvfW

yvfV

yvfU

yvfT

yvfS

yvfR

358 238

442

548

126

685

272

3,510,000bp

rsbQ

rsbP

3,520,000bp

yvfH

ganB

ganA

ganQ

ganP

cycB

ganR

3,530,000bp

yvfG

yvfI

sigL

slrR

epsO

epsN

epsM

epsL

epsK

epsJ

epsI

epsH

epsG

epsF

epsE

epsD

epsC

epsB

3,540,000bp

pnbA

sacB

epsA

racX yveG yveF

padC

388

38

yveA

yvdT

yvdS yvdR

pbpE

cotR

yvdQ

259

clpP

yvdP

pgcM

malL

malK

459 435

458

GeF-seq

ChAP-seq

ChAP-chip

625

levB

3,560,000bp

3,570,000bp

yvdC

malK

yvdJ

mdxG

mdxF

mdxE

mdxD

mdxR

yvdD

yvcT

yvdB

3,580,000bp

3,590,000bp

yvzJ

yvdA

yvcS

yvcR

yvcQ

yvcP

yvpB

yvcN

crh whiA

yvcK

yvcJ

yvcI

trxB

cwlO

yvcD

bmrA

yvzA yvcB

yvcA

hisI

hisA

hisH

hisB

hisD

hisG

nagA

hisZ

yvoF

19

ppaX

59

yvoD

lgt

nagBA

yvoA

hprK

yvnB

130

357

GeF-seq

ChAP-seq

ChAP-chip

519

hisF

pelC

3,610,000bp

yvnA

yvnB

yvmB

cypX

yvmA

3,620,000bp

yvkN

yvlB yvlD yvlC

yvmC

yvlA

yvkC

yvzB

uvrA

uvrB

3,640,000bp

yvkA

yvyE

csbA

swrAA swrAA ctpB

minJ

ftsX

ftsE

557

cccB yvjA

503 345

prfB

secA

yvyD

555

yvzG fliT fliS

fliD

yvyC

fliW csrA

hag

yviE

flgL

flgK

yvyG

flgM yvyF

comFC

comFA comFB

yviA

degU

yvhJ

degS

tagO

600

tuaH

618

GeF-seq

ChAP-seq

ChAP-chip

402

yvkB

3,630,000bp

3,660,000bp

3,670,000bp

lytR

tuaH

tuaG

tuaF

tuaE

tuaC

tuaA tuaA

tuaB

lytC

lytB

393

lytA

gtaB

3,690,000bp

yvzE

ggaB yvzH

mnaA

510

ggaA

164

yvzI

tagA

tagH

tagG

tagF

122 236

283

tagE

tagB

tagC

gerBA

tagD

87

lytD

292

65

gerBB

gerBC

ywtF

yvyI

ywtE

ywtG

pgsA pgsE

pgdS

pgsC

pgsB

359

GeF-seq

ChAP-seq

ChAP-chip

457

tuaD

3,680,000bp

3,710,000bp

rbsR

rbsK

rbsD

rbsA

rbsC

rbsB

ywsB

pgsB

ChAP-chip ChAP-seq

alsR

ywrO

522

GeF-seq

ywsA

620

3,720,000bp

alsD

alsS

406

ywrK

cotG

ywrJ

cotB

cotH

ywrF

ywrE

3,730,000bp

ywrC

ywrD

ywrB

ywrA

3,740,000bp

ywqM

ywqN ywqO

289

ywqB

ywqL

573 133

ywqK

ywqH ywqI

ywqJ

62

ywqG

ywqF

497

ywqE

ptkA

ywqC

ywqA

ywzD

251

ywpF

ywpJ

518

glcR

ssbB

431 438

ywpG

ywpD

ywpE

166

rapD

mscL

fabZ

ywoH

flhP

flhO

mbl

160

usd spoIIID

ywoG

3,760,000bp

ywoG

amtB

ywoF

pucI

ywoD

ywoC

glnK

bcrC

ywoB

ywnH

ywnJ

ywnG

clsA

spoIIQ

3,780,000bp

ywnC

ywnF

mta

ywmA

ywnB

585

3,790,000bp

ywnA

ureC

ureB ureA

ywzE ywzF

ywmF csbD

rapB

moaA

403

fdhD

ywmD ywmE

315

ywmC

spoIID

murAA

ywmB

ywzB

ywlA

atpC

atpD

atpG

atpA

atpH

atpB atpE

atpF

atpI

591 384

298

upp

396

glyA

ywlG

ywlF

ywlE

ywlD

ywlC

ywlB

ywkD

spoIIR

ywkF prmC

racA

prfA

ywkB

242

GeF-seq

ChAP-seq

ChAP-chip

195

3,770,000bp

3,810,000bp

3,820,000bp

ywjG

ywkB maeA

rho rpmEA

tdk

ywjI

murAB

ywjH

fbaA

spo0F

clsB

pyrG

rpoE

acdA

ywjD

3,830,000bp

ywjC

fadF

3,840,000bp

albA sboX sboA

ywiC

ywjB

ywjA

ywiE

narI

narH

narG

arfM

fnr

narK

argS

albD

albE

albF

albG

ywiB

ywhL

pbpG

ywhK

speB

61 664 507

427

ywhH phrF

rapF

589 263

speE

508

GeF-seq

ChAP-seq

ChAP-chip

437

narJ

albC albB

3,860,000bp

pbpG

3,870,000bp

ywhB

ywhD

ywhC

rsfA

ywhA

thrZ

mmr

ywgB

ywgA

ywfO

ywfI

ywzC

ywfM

ywfL

cysL

3,880,000bp

3,890,000bp

ywfH

ywdL

pta

bacF

bacE

bacD

bacC

bacB

bacA

ywfA

rocC

rocB

rocA

rocG

yweA

spsL

spsK

spsJ

spsI

spsG

spsF

spsE

spsD

spsC

spsB

spsA

ywdH

ywdK

ywdJ

ywdI

ywdF

ywdE

ywdD

258

GeF-seq

ChAP-seq

ChAP-chip

161

ung

3,910,000bp

pdxK

ywdD

ywzG

ywcJ

ywdA sacA

sacP

3,920,000bp

vpr

sacT

ywcE

ywcI

ywcH

nfrA

rodA

ywzA

qoxD qoxC

420

qoxB

qoxA

slrA

galT

galK

ywcD

3,940,000bp

ywcB ywcA

cidA lrgB

ywcC

ywbO

efeN

efeM

efeU

thiE

thiM

ywbF

ywbE

ywbI

ywbC

ywbD

173

epr

ywbB

sacX

sacY

ywbA

ywaE

gspA

95

tyrZ

ywaD

ywaF

ywaC

413

GeF-seq

ChAP-seq

ChAP-chip

7

3,930,000bp

3,960,000bp

dltA ywzH

ywaC

menA

dltB

dltD dltC

dltE

3,970,000bp

ilvK

katX

licH

licA licC

licB

licR

aag yxzF

yxlH

3,980,000bp

yxlA

yxlG

yxlF

yxlD yxlE yxlC sigY

cimH

yxkO

cydD

cydC

cydB

ChAP-chip ChAP-seq

yxkI

yxzE

cydA

yxkH

144

GeF-seq

3,990,000bp

3

aldY

msmX

yxkF

yxkC

yxkD

yxjO

galE

149

yxjN

yxjM

yxjL

pepT

yxjJ

yxjI

yxkA

9

314

185

yxjH

yxjG

4,010,000bp

yxjG

yxjA

yxjF

scoB

scoA

yxjC

4,020,000bp

citH

yxjB

yxiT

yxiT

4,030,000bp

4,040,000bp

yxiO

yxiS katE

bglS

licT

hutP

yxiP

yxzJ yxzI yxiK

yxiM

hutI

hutG

hutM

yxiB yxiJ yxiI

yxzG

yxiH

yxiG

yxzC yxiF

yxxG

wapA

yxxF

82 141

578

hutU

234

382

yxiE

535

541

bglH

bglP

yxxE yxxD

545

97

yxiD

yxiC

abnB

yxzL

pdp

383 409

363

GeF-seq

ChAP-seq

ChAP-chip

638

deaD

hutH

4,060,000bp

4,070,000bp

yxeE

pdp

nupC

deoC

deoR

yxxB

yxeR

yxeQ

yxeP

yxeO

yxeN

yxeM

yxeL

yxeI yxeJ

yxeK

yxeH

yxeG

yxeF

yxeD

4,080,000bp

4,090,000bp

yxeB

iolR

yxeC

yxeA yxdM

yxdL

yxdK

yxdJ

iolJ

iolI

iolH

iolG

iolF

iolE

iolD

iolC

iolB

iolS

yxcE

yxcD

csbC

yxbG

mmsA

htpG

yxcA

yxnB aslA

yxbB

yxbF

yxbD

yxbC

537 60 494

338 311

534

asnH

700

GeF-seq

ChAP-seq

ChAP-chip

47

aldX

4,110,000bp

asnH

yxaM

yxaI

yxaL

yxaJ

666

yxaH

qodI

yxzK yxaC

yxaF

yxaD

gntR

yxaB

gntK

gntP

gntZ

ahpC

ahpF

yydK

glxK

599 245 584 154 544 51

4,130,000bp

bglA

274

yyzN

yyzE

4,140,000bp

fbp

yydJ

583

yydI

yydH

565

125 492 397 416 46

yydG

527

yycS

yydF

430

yydD

100 483 449

yydC

225

yydB

184

yydA

yyzF

rapG

yycR

yyzG

yycQ yycP

yycO

phrG

yycN

rocR

argI

rocE

rocD

yyzO

479

596

htrC

70

yycJ

yycI

322

GeF-seq

ChAP-seq

ChAP-chip

26

yxnA

4,120,000bp

4,160,000bp

yycD

yycI

walH

walK

walR

yycE

dnaC

yycA

cotF

yyzB

rplI

yybT

yybS

408

ChAP-seq GeF-seq

4,210,000bp

yyaC

engD

yyaE

GeF-seq

ChAP-seq

ChAP-chip

276

yyzH

ppaC

yybR

yyzM yyaD

yyaB

parB

151 329

341

parA

noc

rsmG

trmF

trmE

jag

oxaAA

592

rnpA

rpmH

4,180,000bp

yybO

yybP

414

ChAP-chip

29

trnY-Lys trnY-Glu trnY-Asp trnY-Phe purA

yycB yycC

4,170,000bp

yybN

yyzJ yyzI

447

yyzL yyzK

674

yybM

yybL

yybK

yybJ

yybG

4,190,000bp

yybE

yybD

yybC

yyaT

yyaS

yyaQ

yyaP

yyaO yyaN

yyaM

yyaL

yyaJ

engD

ssbA yybI

178 365 466 471 469

yybH

yybF

yybB

yybA

yyaR

tetB

tetL

220

490

yyaK

697

325

maa

53

yyaH

387

ccpB

exoAA

rpsR

rpsF