Ph.D. (Inorganic Chemistry) 1976 ... 1976-1980 - Assistant Professor of
Chemistry, University of Rochester ... A. P. Sloan Research Fellow, 1980-1981.
Camille ...
GEORGE L. McLENDON Curriculum Vitae
EDUCATION: B. S. (magna cum laude) 1972 University of Texas at El Paso Ph.D. (Inorganic Chemistry) 1976 Texas A&M University Thesis advisor: A. E. Martell RESEARCH INTERESTS: Macromolecular Recognition (Protein-Protein; Protein-Nucleic Acid) (Long Distance) Electron Transfer in Chemical and Biological Systems Protein Engineering (site directed mutagenesis) PROFESSIONAL EXPERIENCE: 2008-present Dean of the Faculty of Arts and Sciences and Dean of Trinity College Duke University 2004-2008 Dean of the Faculty of Arts & Sciences, Duke University 2004-present Professor of Chemistry and Professor of BioChemistry, Duke University 1996-2004 - Chair, Department of Chemistry, Princeton University 1995-2004 - Russell Wellman Moore Professor of Chemistry, Princeton University 1994-1995 - Chair, Department of Chemistry, University of Rochester 1990-1995 - Tracy H. Harris Professor of Chemistry, University of Rochester 1990-1995 - Professor of Biochemistry, University of Rochester 1984-1990 - Professor of Chemistry, University of Rochester 1980-1984 - Associate Professor of Chemistry, University of Rochester 1976-1980 - Assistant Professor of Chemistry, University of Rochester 1973-1976 - NSF Fellow-, University Health Fellow, Texas A&M University
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AWARDS AND HONORS: Academy of Distinguished Graduates Award, Texas A&M University 1998 Golden Nugget Award: Outstanding Alumnus, University of Texas, El Paso, 1996 American Chemical Society Akron Section Award, 1992 American Chemical Society Eli Lilly Award in Biological Chemistry, 1990 Fellow, Worcester College, Oxford (Honorary), 1990 Guggenheim Fellow, 1989-1990 American Chemical Society Pure Chemistry Award, 1987 A. P. Sloan Research Fellow, 1980-1981 Camille and Henry Dreyfus Teacher Scholar, 1979-1984 Graduate Research Award Texas A&K 1976 S. Dabney Award, Phi Lambda Upsilon, 1976 ENDOWED LECTURESHIPS: A.D. Little Lectures, MIT Frontiers Lectures, University of Iowa H. Wood Lecturer, Case Western Reserve University Rosemont Lecturer, Johns Hopkins University Watkins Lecturer, Wichita State University Frontiers Lecture, Texas A & M University W. Denkewalter Lecturer, Loyola University Research Scholar Lecturer, Drew University Merck-Bucknell Lecturer, Bucknell University W. Heinlen Hall Lecturer, Bowling Green State University Arthur Vernon Lecturer, Northeastern University R. A. Welch Lecturer Naff Memorial Lecturer, University of Kentucky
INVITED LECTURES: Over 200, including >100 US universities and ~30 nations around the world PROFESSIONAL SERVICE: Chair, Review Committee, Department of Chemistry, Texas A& M University, April, 2005 Chair, Review Committee, Chemistry Unit, Ecole Polytechnique Fdderale de Lausanne, January 2005 Award Committee for the ACS Award in Pure Chemistry, (1999-2001) Chair, Bioinorganic Subdivision, American Chemical Society (1998-1999) National Science Foundation Advisory Board for Chemistry (1988-1991) Visiting Committee, Solar Energy Research Institute (1987-1990, Chair 1990) Member Editorial Boards: Accounts of Chemical Research (1987-1993), Journal of Biological lnorganic Chemistry (1995- ). Advisory Panel for Physical Chemistry, NSF (1987) "Physics News" Committee for Chemical Physics, American Physical Society (1988-1991) Member, Executive Board, Rochester Section, American Chemical Society (1978-1982) Chairman, Harrison Howe Award Committee, Rochester Section, American Chemical Society (1982) Chair Elect and Chair, Bioinorganic Subdivision, American Chemical Society (1998-1999) 2
REVIEW ACTIVITIES: National Institutes of Health: Special Study Section on Research Resources, Physical Biochemistry Study Section (1995 - 2000 ). MBT Study Section (2000-2005). National Science Foundation: Biophysics Review Panel National Science Foundation: Presidential Faculty Fellows Selection Committee Department of Energy/BES: Review Panel for Electron Transfer Manuscript Reviewer for: Journal of the American Chemical Society, Biochemistry, Inorganic Chimica Acts, Biophysical Chemistry, Nature, Science, Inorganic Chemistry, Journal of Molecular Biology, Coordination Chemistry Reviews, Journal of Biological Chemistry, Journal of Mathematics Science, Journal of Physical Chemistry, Journal of Chemical Physics, Journal of Biological Inorganic Chemistry Proposal Reviewer for: National Science Foundation (Inorganic Chemistry, Chemical Dynamics, Chemical Physics, Biophysics, International Programs Programs Instrumentation), Department of Energy, Petroleum Research Foundation, Research Corporation. CONFERENCE ORGANIZER: Rochester Conference on Photoinduced Electron Transfer Chair electron Donor Acceptor Gordon Conference ACS Pacific Basins Meeting Symposium on Long Range Electron Transfer Electrochemical Society Symposium on Electron Transfer in Complex Systems Materials Research Society New Directions in Cluster Research NATO Workshop on Photocatalysis
TEACHING – DUKE UNIVERSITY: Chem 22 – General Chemistry Chem 49S – Energy and Society: From Molecules to Policy MMS 95
Entrepreneurship (joint with Fuqua school of Business)
Econ 99S
Biotechnology Startups
TEACHING – PRINCETON UNIVERSITY: Chem 522 Advanced Inorganic Chemistry Chem 407 Inorganic Chemistry I 3
Freshman Research Seminar 123 Chem 202 General Chemistry Chem 371 Experimental Chemistry Chem 201 General Chemistry Chem 203 Freshman Chemistry Chem 307 Junior Level Inorganic Chemistry Chem 509 Biophysical Chemistry Cbem 50S Physical Biochemistry Chem 542 Inorganic Biochemistry Chem 542 Biophysics Chem 536 Topics in Organic Chemistry: Chemistry of Drug Development CURRENT COMMITTEE SERVICE: DUKE UNIVERSITY President’s Senior Leadership Group University Priorities Committee COMMITTEE SERVICE: PRINCETON UNIVERSITY Development Leadership Council Committee on the Implementation of the Wythes Plan McGraw Center for Teaching and Learning Advisory Committee (Chair) Environmental, Safety, and Risk Management Ad Hoc Advisory Committee on Implementation of the Wythes Report Institute for Integrative Genomics, Executive Committee Graduate Admissions Committee, Chemistry Department UNIVERSITY SERVICE: Princeton Faculty Advisory Committee on Appointments and Advancements Chemistry Department Executive Committee Graduate Admissions Committee, Chemistry Department Search Committee for Director Princeton Materials Institute Priorities Committee (sets operating budget for University) Review Committee: University Science Fellowships
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OTHER EXTERNAL SERVICE: Chair of Visiting Committee; Department of Chemistry, Vanderbilt University, Special Study Section: NIH Panel on Active Sensors: ONR ADVISORY BOARDS:
Labcyte:
Chief scientific advisor (Advanced technologies for drug discovery)
Tetralogic:
Chair, Scientific Advisory Board Member, Board of Directors (Apoptosis based diagnostics and therapeutics)
Amplyx
Scientific Advisory Board Drug modification for improved PK
Viamet
Scientific Advisory Board Metalloenzyme drug targeting
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PUBLICATIONS: 1.
Stabilities of Binuclear Cobalt Oxygen Adducts: A Linear Free Energy Relationship, G. McLendon and A. E. Martell, Chem. Commun. 1975, 223.
2.
Interaction of Co(II)-Glycylglycine Chelates with Molecular Oxygen. Species in Solution, G. McLendon and A. E. Martell, Inorg. Chem. 1975, 14, 1423.
3.
Cobalt Complexes of Ethylenediamine-N,N'-diacetic Acid and Ethylene-diamine-N,N’-diacetic Acid: Two-Nitrogen Oxygen Carriers, G. McLendon, R J. Motekaitis, and A. E. Martell, Inorg. Chem. 1975, 14, 1993.
4.
Combination of Dioxygen with N,N-Bis (2-Aminoethyl) Glycinatocobalt-(II) and with Diethylenetriamine-N-Acetatocoba1t (II), G. McLendon, D. MacMillan, M. Hariharan, and A. E. Martell, Inorg. Chem. 1975, 15, 2322.
5.
Oxygen Complex Formation of Cobalt(II)-tris(2-aminoethyl)amine, G. McLendon and A. E. Martell, J. Coord. Chem 1975, 4, 235.
6.
Inorganic Oxygen Catriers as Models for Biological Systems, G. McLendon and A. E. Martell, Coord. Chem. Rev. 1976, 19, 1.
7.
Oxygen Complexation by Fused Pyridyl Cobaltous Chelates: Equilibria, Reactions and Electron Structure of the Complexes, R. F. Bogucki, G. McLendon, and A. E. Martell, J. Am. Chem. Soc. 1976, 98, 3202,
8.
Kinetics and Mechanism of the Dimerization of the Fe(III)-EDTA Complex, G. McLendon, A. E. Martell, and R. J. Motekaitis, Inorg. Chem. 1976, 15, 2306.
9.
Dioxygen Complexation by Cobalt Amino Acid and Peptide Complexes. I. Stoichiometry and Equilibria, G. McLendon, W. Harris, and A. E. Martell, J. Am. Chem. Soc. 1976, 98, 8379.
10.
Redox Properties of Peroxo and Superoxo Bridged Cobalt Complexes, G. McLendon and A. E. Martell, Inorg. Chem. 1976, 15, 2662.
11.
Sequence Structure Relationships in Metalloproteins. I. A Proposed Coordination Model for Plastocyanine, G. McLendon and A. E. Martell, J. lnorg. Nucl. Chem. Bioinorg. Sect. 1977, 39, 191.
12.
Primary-Tertiary Structure Relationships in Metalloproteins. A Predictive Model of Hemerythrin, G. McLendon, W, Harris, and A. E. Martell, Bioorg. Chem. 1977, 7, 117.
13.
Iron(II)-tetrasulfophthalocyanine as an Oxygen Carrier in Aqueous Solution, G. McLendon and A. E. Martell, Inorg. Chem. 1977, 16, 1812.
14.
Electronic Spectra and Structure of a Mononuclear Dioxygen Complex [Co(CN)5O2]3-, G. McLendon, S. Pickens, and A. E. Martell, Inorg. Chem 1977, 16, 1812.
15.
A Correlation Between Myoglobin Thermodynamic Stabilities and Species Metabolic Rates, G. McLendon, Biochem. Biophys. Res. Comm. 1977, 77, 959. 6
16.
Electronic Spectra and Structure of Dioxygen Complexes II. Bis(N,N'dimethylethylene-diamine)chloro Superoxo Cobalt (II), S. Pickens, G. McLendon, A. B. P. Lever and A. E. Martell, Inorg. Chem. 1978, 17, 2190.
17.
Model Systems for Blue Copper Proteins. An Electrochemical Study of a Mercaptopropionylglycine, G. McLendon, J. Inorg. Nucl. Cham. 1978, 40, 755.
18.
Macrocycle Promoted Oxygenation Reactions: Equatorial and Axial Ligand Effects, G. McLendon and M. Mason, Inorg. Chem. 1978, 17, 362.
19.
Axial Ligand Effects on Myoglobin Stability, G. McLendon and K. Sandberg, J. Biol. Chem. 1978, 253, 3913.
20.
Equilibrium and Kinetic Studies of Unfolding of Homologous Cytocbrome c's, G. McLendon and M Smith, J. Biol Chem. 1978, 253, 4404.
21.
Is Protein Turnover Thermodynamically Controlled? G. McLendon and E. Radany, J. Biol. Chem 1978, 253, 6335.
22.
Metal Binding and Radioprotective Properties of Glycyl Histamine, R. O'Connor, A.E. Martell, and G. McLendon, Int. J. Rad. Res. 1979.
23.
Metalloporphyrin-Ligand Equilibria: A Ligand Field Rationale, G. McLendon and M. Bailey, 1norg. Chem 1979, 18, 2120.
24.
An Electrochemical Study of Dioxygen Adducts, W. Harris, G. McLendon, M. Mason, and A. E. Martell, Inorg. Chem. 1980, 19, 20.
25.
Application of Marcus Theory to the Electron Transfer Reactions of Metal Bound Dioxygen, G. McLendon and W. Mooney, Inorg. Chem. 1980, 19, 12.
26.
Functional Design of Heme Proteins: Reaction with Linear Ligands, M. Smith and G. McLendon, J. Am. Chem. Soc. 1980, 102, 5666.
27.
Metal Electronic Effects on Myoglobin Conformational Stability, G. McLendon and P. Murphy, J. Biol. Chem. 1980, 255, 4035.
28.
Preparation and Conformational Characterization of Cr(III) Hemoglobin, M. Fiechtner, G. McLendon, and M. Bailey, Biochem. Biophys. Res. Comm. 1980, 92, 277.
29.
Metalloporphyrins Catalyze the Photoreduction of Water to H2, G. McLendon and D. S. Miller, Chem. Comm. 1980, 533.
30.
Structural Characterization of the Cyanophycin Granule Polypeptide from Alabena Cylindrica, G. McLendon, N. Lowry, and R. Simon, Biochim. Biophys. Acta 1980, 626, 277.
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31.
Assignment of the Quarternary Structure of Fe/Zn Hybrid Hemoglobins: Implications for Allosteric Theories, M. Fiechtner, M. Bailey, and G. McLendon, Biochem. Biophys, Res. Comm. 1980, 96, 618.
32.
Model Systems for Photocatalytic Water Reduction: Role of pH and Metal Colloidal Catalysts, D. Miller and G. McLendon, Inorg. Chem. 1981, 20, 950.
33.
Catalytic Water Reduction at Colloidal Metal "Microelectrodes": Theory and Experiment, D. Miller, A. Bard, G. McLendon, and J. Ferguson, J. Am. Chem. Soc. 1981, 102, 5336.
34.
Comparative Magnetic Resonance of Cytochrome c and Its Active Site Octapeptide, M. Smith and G. McLendon, J. Am. Chem Soc. 1981, 102, 4912.
35.
Quantitative Electrochemical Kinetics Studies of "Microelectrodes": Catalytic Water Reduction by Methyl Viologen/Colloidal Platinum, D. Miller and G. McLendon, J. Am. Chem. Soc. 1981, 102, 6791.
36.
Outer Sphere Electron Transfer Reactions of the Isolated Active Site Heme Octapeptide from Cytochrome c, G. McLendon and M. Smith, Inorg. Chem. 1982, 22, 847.
37.
Zwitterion Mediator Quenchers: Coulombic Minimization of the Back Reaction in Photocatalysis, P. Brugger, M. Gratzel, T. Guarr, and G. McLendon. J. Phys. Chem. 1982, 86, 944,
38.
Collisionless Photoinduced Electron Transfer in Rigid Glycerol Solution, T. Guarr, M. McGuire, S. Strauch, and G. McLendon, J. Am. Chem. Soc. 1983, 105, 616.
39.
Quantum Effects of High Frequency Modes in Inorganic Electron Transfer. Kinetic Isotope Effects in Redox Reactions of Fe(aq), T. Guarr, E. Buhks, and G. McLendon, J. Am. Chem. Soc. 1983, 105, 3763.
40.
Photocatalytic Water Reduction to H2. Principles of Catalysis by Colloidal Metal "Microelectrodes", G. McLendon, in Energy Resources Through Photochemistry, M. Gratzel (ed.), Academic Press, New York, 1983.
41.
The Distance Dependence of Photoinduced Electron Transfer: Time Resolved Electron Transfer Emission Quenching in Rigid Solution, S. Strauch, G. McLendon, M. McGuire, and T. Guarr, J. Phys. Chem. 1983, 87, 3579.
42.
Bimetallic Porphyrins: Synthesis and Rapid Intramolecular Electron Transfer of Meso Tritolyl Monopyridyl Ruthenium (III) Pentaamine Porphyrin, C. Franco and G. McLendon, Inorg. Chem. 1984, 23, 2370.
43.
Photoinduced Electron Transfer within a Protein Complex Formed Between Physiological Partners: Reduction of Fe(III) Cytochrome b5 by α2Zn β2Fe(III)CN Hemoglobin, K. Simolo, G. McLendon, A. G. Mauk, and M. Mauk, J. Am. Chem. Soc. 1984, 106, 5012.
44.
Kinetics of CO Binding to Cytochrome c Peroxidase: pH and CO Concentration Effects, A. English, G. McLendon, and K Taylor, J. Am. Chem. Soc. 1984, 106, 6448.
45.
Quenching of Zn Cytochrome c Excited States by Cytochrome b5, J. Winkler, D. Nocera, G. McLendon, and H. Gray, J. Am. Chem. Soc. 1985, 107, 739. 8
46.
Long Range Photoinduced Electron Transfer in a Rigid Polymer, T. Guarr, M. E. McGuire, and G. McLendon, J. Am. Chem. Soc. 1985, 107, 5104.
47.
Characterization of Partially Ligated Hemoglobins: NMR, CD, and Stopped Flow Studies of ZnFe Hybrid Hemoglobins, K. Simolo, S. Chen, G. Stucky, and G. McLendon, J. Am. Chem. Soc. 1985, 107, 2865.
48.
Quantum Mechanical Effects in Inorganic Electron Transfer, T. Guarr and G. McLendon, Coord. Chem. Rev. 1985, 68, 1.
49.
Long Distance Electron Transfer in Polymers and Proteins, G. McLendon, K. Simolo, E. Magner, K. Taylor, T. Guarr, M. McGuire, and J. Miller, Coord. Chem. Rev., 1985, 64, 113.
50.
Dependence of Biological Electron Transfer Rates an Exothermicity: The Cytochrome c/Cytochrome b5 Couple, G. McLendon and J. R Miller, J Am. Chem. Soc. 1985, 107, 7811.
51.
Electrocatalysis and Photocatalysis, G. McLendon and R. Memming in Photocatalysis, NATO ASI Series 1986, 174, 703.
52.
Determinants of Hemoglobin Allostery: EXAFS Studies of ZnFe Hybrids, Z. R Korszum, G. Stucky, K. Simolo, K. Moffat and G. McLendon, Biochemistry 1986, 25, 3773.
53.
Does Solvent Relaxation Control Electron Transfer Rates: A Study in Rigid Solution, M. McGuire and G. McLendon, J. Phys. Chem 1986, 90, 2549.
54.
Picosecond Time Resolved Fluorescence Spectroscopy of Ethidium Bromide. Evidence for a Non-Activated Reaction, J. Sommer, M. McGuire, G. McLendon, and T. Nordlund, J. Phys. Chem. 1986, 90, 5173.
55.
Direct Measurements of Intramolecular Electron Transfer Rates Between Cytochrome c and Cytochrome c Peroxidase. Effects of Exothermicity and Sequence on Rate, E. Chung, G, McLendon, K. Taylor, A. English, and J. R. Miller, Proc. Natl. Acad. Sci. 1986, 83, 1330.
56.
Bifunctional Porphyrins: [Meso(tritolyl (pyridyl Ru(III)(NH3)L' L = NH3,-, Pyr, 5Clpyr)], C. Franco and G. McLendon, Proc. NA TO Workshop Photocatalysis, Reidel Press 1986, 174, 189.
57.
The Tunnel at the End of the Light: Thermal and Photoinduced Long Distance Electron Transfer in Proteins, G. McLendon, J. R. Mller, K. Simolo, A. G. Mauk, and A. English, ACS Simolo, A. G. Mauk and A. English, ACS Symposium Series 1986, 307, 152, A. B. P. Lever (ed.), American Chemical Society, Washington, D.C.
58.
Photophysics of Quantized Colloidal Semiconductors. Dramatic Luminescence Enhancement by Binding of Simple Amines, T. Dannhauser, M. O'Neill, K Johanssen, D. Whitten, and G. McLendon, J. Phys. Chem. 1986, 90, 6047.
59.
Photoinduced Long Range Electron Transfer in the Zn-Substituted Cytochrome c: Cytchrome c Peroxidase Complex, K. T. Conklin and G. McLendon, Inorg. Chem. 1986, 25, 4804. 9
60.
Time Resolved Fluorescence Spectra of Ethidium Bromide, J. Sommer, M, McGuire, G. McLendon, and T. Nordlund, in Ultrafast Phenomena, G. Fleming (ed.), 1986, p. 367.
61.
Reactions of Cytochrome b2 with Metal Substituted Cytochrame c's: Evidence for Conformational Gating, G. McLendon, K. Pardue, and P. Bak, J. Am. Chem. Soc. 1987, 109, 7540.
62.
Synthesis and Electron Transfer Rates of Coplanar Bis Porphyrins: Models for Heme Protein Electron Transfer Reactions, D. Heiler, G. McLendon, and P, Rogalskyj, J. Am. Chem. Soc. 1987, 109, 604.
63.
The Dependence of Biological Electron Transfer Rates on Exothermicity: The Cytochrome c: Cytochrome c Peroxidase (ES) Couple, K. Taylor and G. McLendon, J. Am. Chem. Soc. 1987, 110, 3345.
64.
Electronic and Nuclear Factors in Intramolecular Electron Transfer Processes, F. Scandola and G. McLendon, Nouv. J. Chim. 1987, 11, 191.
65.
Replacement of the Invariant Lysine 77 by Arginine in Yeast iso 1 Cytochrome c Results in Enhanced and Normal Activities in vitro and in vivo, D. Holzschu, L. Principio, K. Taylor, R. Rao, G. McLendon, and F. Sherman, J. Biol. Chem. 1987, 262, 7125.
66.
Electrophoresis, G. McLendon, in The World Book Encvclopedia, 1987.
67.
Reactions of Delocalized Excited States in Restricted Environments, C. Backer, J. R. Corvan, T. Dannhauser, B. Suddaby, K. Takaji, G. McLendon, and D. Whitten, NATO ASI Series Reidel Press, 1987.
68.
Vibrational Energy Relaxation Processes in Heme Proteins, L. Genberg. F. Heisel, D. Miller, and G. McLendon, J. Phys. Chem. 1987, 91, 5521.
69.
The Control of Long Distance Electron Transfer in Biological Systems, G. McLendon, Acc Chem. Res. 1988, 21, 160.
70.
Site Specific Mutation at the Cytochrome c: Cytochrome c Peroxidase Binding Site: Effects on Electron Transfer Rates, J. Hazzard, G, McLendon, M. Cusanovich, G. Tollin, and F. Sherman, Biochemistry 1988, 27, 4445.
71.
Replacements of the Evolutionarily Invariant Lys 32 in Yeast Cytochrome c: Effects on Binding and Reactivity with Physiological Partners, L. Principio, K. Conklin, J. Short, G. McLendon, G. Das, D. Hickey, and F. Sherman, J. Biol. Chem. 1988, 263, 18290.
72.
Determinants of Electron Transfer Rates: The Cytochrome c:Cytochrome c Peroxidase System, J. S. Rogalskyj, E. Magner, and G. McLendon, Prog. Clin. Biol. Res. 1988, 274, 387
73.
Formation of a Tight Binding Complex Inhibits Electron Transfer Between Cytochrome c and Cytochrome c Peroxidase, J. Hazzard, G. McLendon, M. Cusanovich, and G. Tollin, Biochem. Biophys, Res. Comm. 1988, 151, 429.
74.
Long Distance Electron Transfer in Biological Systems, G. McLendon, Welch Foundation Lecture Series, W. O. Baker (ed.), 1988. 10
75.
There and Back Again: Long Distance Electron Transfer from Semiconductors to Proteins, M. O’Neil, D. Corvan, K. Johansson, and G. McLendon, in Photochemical Energy Conversion, J. Norris (ed.), American Elsevier, New York, 1988.
76.
Energy Relaxation in Proteins Probed by Transient Gratings, L. Genberg, D. Miller, and G. McLendon in Ultrafast Phenomena, AlP Conf. Proc. 1988, 72, 671.
77.
Fractal Structures in Semiconductor Clusters, M. O'Neil and G. McLendon, Chem. Phys. Lett. 1988, 147, 565.
78.
Thermodynamic Stabilities of Yeast iso-1 Having Amino Acid Substitutions for Lysine 32, D. Hickey, G. Das, G. McLendon, and F. Sherman, J. Biol. Chem. 1988, 263, 18298.
79.
Energy Relaxation in Heme Proteins, L. Genberg, F. Heisel, G. McLendon, and R. J. D. Miller, J. Lumin., 1988, 40, 573.
80.
Dramatic Thermostabilization of Yeast iso-1 Cytochrome c by an Asn 57 → Ile 57 Replacement, D. Hickey, G. Das, G. McLendon, D. McLendon, and F. Sherman, Proc. Natl. Acad. Sci. U.S.A., 1989, 86, 496.
81.
Photochemical Generation and Reactions of Heme Cation Radicals in Heme Proteins. E. Magner and G. McLendon, Biochem. Biophys. Res. Comm. 1989, 159, 472.
82.
Electron Transfer Reactivity of Excited State and Ground State Zn Cytochrome c, E. Magner and G. McLendon, J. Phys. Chem. 1989, 93, 7130.
83.
Conformational Dynamics and Electron Transfer in Protein Complexes, G. McLendon, J. Inorg. Biochem. 1989, 36, 206,
84.
Electron Transfer Rates in Mitochondrial Proteins: Regulation and Specificity, G. McLendon, Q. Zhang, K. Pardue, F, Sherman. A. Corin, R. Ciacarelli, J. Falvo, and D. Holzschu, in Molecular Electronics: Biosensors and Biocomputers, F. T. Hong (ed.), Plenum Press, 1989, pp. 131-141.
85.
Picosecond Measurements of Exciton Trapping in Semiconductor Clusters, M. O’Neil, J. Marohn, and G. McLendon, Chem. Phys. Lett. 1990, 168, 208.
86.
Dynamics of Electron Hole Pair Recombination in Semiconductor Clusters, M. O’Neil and G. McLendon, J. Phys. Chem. 1990, 94, 4356.
87.
Electronic Coupling and Protein Dynamics in Biological Electron-Transfer Reactions, J. S. Bashkin and G. McLendon, in Electron Transfer in Biology and the Solid State: Inorganic Compounds with Unusual Properties, ACS Advances in Chemistry Series No. 226, M. K. Johnson, R. B. King, D. M. Kurtz, Jr., C. Kutal, M. L. Norton, and R. A. Scott (eds.), American Chemical Society, Washington, D.C., 1990, pp. 147-159.
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88.
Influence of Medium Dynamics on Solvation and Charge Separation Reactions: Comparison of a Simple Alcohol and a Protein "Solvent", J. Bashkin, G. McLendon, S. Mukamel, and J. Marohn, J. Phys. Chem. 1990, 94, 4758.
89.
Protein Conformational "Annealing": Binding to Cytochrome c Refolds the Active Site Region of Recombinant Cytochrome c Peroxidase, R. Hake, G. McLendon, and A. Corin, Biochem. Biophys. Res. Comm. 1990, 172, 1157.
90.
Macromolecular Recognition in the Cytochrome c:Cytochrome c Peroxidase Complex Involves Fast Two-Dimensional Diffusion, Q. P. Zhang, J. Marohn, and G. McLendon, J. Phys. Chem. 1990, 94, 8628.
91.
Enhanced Thermal and Photochemical Reactivity at Charged Interfaces in Microheterogeneous Media, C. A. Backer, J. R. Corvan, S. P. Spooner, D. Armitage, G. McLendon, and D. G. Whitten, J. Surf. Sci. Tech. 1990, 6, 59.
92.
Reorganization Energies for Protein-to-Protein Electron Transfer and Interfacial Dynamics: Playing Fast and Loose, G. McLendon, R. Hake, A. Corin, and Q. Zhang, Mol. Cryst. Lig. Cryst. 1991, 194, 225.
93.
Probing the Role of Surface Residues in the Complex Formed Between Cytochrome c Peroxidase and Cytochrome c, Q. Zhang, R. Hake, V. Billstone, J. Simmons, J. Falvo, D. Holzschu, K. Lu, G. McLendon, and A. Corin, Mol. Cryst. Liq. Cryst. 1991, 194, 343.
94.
The Dynamics and Oxidation State Dependence of Complex Formation Between Cytochrome c Peroxidase and Cytochrome c, R. Hake, Q. Zhang, L. Marohn, G. McLendon, and A. Corin, Mol. Cryst. Lig. Cryst. 1991, 194, 351.
95.
Direct Observation of Picosecond "Protein Quakes” in Hemoglobin, L. Genberg, L. Richard, R. J. D. Miller, and G. McLendon, Science 1991, 251, 1051.
96.
Control of Biological Electron Transport via Molecular Recognition and Binding: The "Velcro" Model, G. McLendon, in Structure and Bonding, Vol. 75, Springer-Verlag, Berlin, Heidelberg, 1991, pp. 159-174.
97.
Electron Transfer Between Bound Proteins, G. McLendon, in Metal Ions in Biological Systems, Vol. 27, H. Sigel (ed.), Marcel Dekker, New York, 1991, pp. 183-198.
98.
The Effect of Size Restriction on Silver Bromide. A Dramatic Enhancement of Free Exciton Luminescence, K. P. Johansson, G. McLendon and A. P. Marchetti. Chem. Phys. Lett. 1991, 179, 321.
99.
Migration of Small Molecules Through the Structure of Hemoglobins: Evidence for Gating in a Protein Electron Transfer Reaction, J. Feitelson and G. McLendon, Biochemistry 1991, 30, 5051.
100. Dependence of Electron Transfer Rate on Donor-Acceptor Angle in Bis-Porphyrin Adducts, A. Helms, D. Heiler, and G. McLendon J. Am. Chem. Soc. 1991, 113, 4325. 101. Distance and Angle Effects on Electron Transfer Rates in Chemistry and Biology, G. L. McLendon and A. Helms, in Advances in Electron Transfer Reactions. Vol. 1, P. Mariano (ed.), JAI Press, Inc., New York, 1991, pp. 149-161. 12
102. Electron Transfer in Inorganic, Organic, and Biological Systerns, J. R. Bolton, N. Mataga and G. McLendon (eds.), ACS Adv. Chem. Ser. 228, American Chemical Society, Washington, D.C., 1991. 103. Effects of Reaction Free Energy in Biological Electron Transfer In Vitro and In Vivo, G. McLendon, D. Hickey, A. Berghuis, F. Sherman, and G. Brayer, in Electron Transfer in Inorganic, Organic, and Biological Systems, J. R. Bolton, N. Mataga, and G. McLendon (eds.), ACS Adv. Chem. Ser. 228, American Chemical Society, Washington, D.C., 1991, pp. 179-189. 104. Crystal Structure and Chemical Reactivity of Heme Phenoxide Adducts, A. M. Helms, W. D. Jones, and G. McLendon, J. Coord. Chem. 1991, 23, 351. 105. Enhanced Thermodynamic Stabilities of Yeast Iso-1-cytochromes c with Amino Acid Replacements at Positions 52 and 102, D. R. Hickey, A. M. Berghuis, G. Lafond, J. A. Jaeger, T. S. Cardillo, D. McLendon, G. Das, F. Sherman, G. D. Brayer, and G. McLendon, J. Biol. Chem. 1991, 266, 11686. 106. Subunit Interactions Change the Heme Active-Site Geometry in p-Cresol Methyl- Hydroxylase, G. McLendon, S. Bagby, J. A. Charman, P. C. Driscoll, W. S. McIntire, F. S. Mathews, and H. A. O. Hill, Proc. Natl. Acad. Sci. USA 1991, 88, 9463. 107. The Role of the Intemal Hydrogen Bond Network in First-Order Protein Electron Transfer Between Saccharmoyces cerevisiae Iso-1-cytochrome c and Bovine Microsomal Cytochrome b5, D. Whitford, Y. Gao, G. J. Pielak, R. J. P. Williams, G. McLendon, and F. Sherman, Eur. J. Biochem. 1991, 200, 359. 108. Direct Electrochemistry of Proteins: Investigations of Yeast Cytochrome c Mutants and Their Complexes with Cytochrome b5, A. L. Burrows, L.-H. Guo, H. A. O. Hill, G. McLendon, and F. Sherman, Eur. J. Biochem. 1991, 202, 543. 109. Effects of Surface Amino Acid Replacements in Cytochrome c Peroxidase on Complex Formation with Cytochrome c, A. F. Corin, G. McLendon, Q. Zhang, R. A. Hake, J. Falvo, K. S. Lu, R. B. Ciccarelli, and D. Holzschu, Biochemistry 1991, 30, 11585. 110. Interactions in Multi-Subunit Redox Proteins. NMR Study of the Cytochrome Subunit of p-Cresolmethylhydroxylase, W. S. McIntire, F. S. Mathews, S. Bagby, J. A. Charman, H.A.O. Hill, P. C. Driscoll, and G. McLendon, in Flavins and Flavoproteins 1990, Proceedings of the Tenth International Symposium, Como, Italy, July 15-20, 1990, B. Curti, S. Rouchi, and G. Zanetti (eds.), Walter de Gruyter, Berlin, New York, 1991, pp. 809-812. 111. Electron Transfer Between Proteins, G. McLendon, in Radiation Research: A 20th Century Perspective, Vol. 1, W. C. Dewey, M. Edington, R. L M. Fry, E. J. Hall and G. F. Whitmore (eds.), Academic Press, San Diego, CA, 1991, p. 51, 112. Protein to Protein Electron Transfer, G. McLendon, in Radiation Research, A 20th Century Perspective, Vol. 2, W. C. Dewey, M. Edington, R. J. M. Fry, E. J. Hall, and G. F. Whitmore (eds.), Academic Press, San Diego. CA, 1992, pp. 75-80. 113. Electron-proton Coupling in Cytochrome c Studied Using Protein Variants, Y. Gao, G. McLendon, G. J. Pielak, and R. J. P. Williams, Eur. J. Biochem. 1992, 204, 337. 13
114. Effect of Size Restriction on the Static and Dynamic Emission Behavior of Silver Bromide, K. Johansson, A. P. Marchetti, and G. L. McLendon, J. Phys. Chem. 1992, 96, 2873-2879. 115. Spectroscopic Studies of Quantized Silver Bromide Crystallites, K. P. Johansson, G. L. McLendon, and A. P. Marchetti, in Proceedings of the Society for Imaging Science and Technologv. Symposium on Electronic.and Ionic Properties of Silver Halides, B. Levy (ed.), The Society for Imaging Science and Technology, Springfield, VA, 1992, p. 287. 116. Effect of the Asn52 → Ile Mutation on the Redox Potential of Yeast Cytochrome c: Theory and Experiment, B. Langen, G. D. Brayer, A. M, Berghuis, G. McLendon, F. Sherman, and A. Warshel, J. Mol. Biol. 1992, 224, 589. 117. Interprotein Electron Transfer, G. McLendon and R. Hake, Chem. Rev. 1992, 92, 481. 118. Redox-Dependent Molecular Recognition in Proteins: Site-Directed Mutagenesis Suggests That Cytochrome c Oxidation State Governs Binding and Recognition to Cytochrome c Peroxidase, R. Hake, G. McLendon, A. Corin, and D. Holzschu, J. Am. Chem. Soc. 1992, 114, 5442. 119. Tuning the Redox Potential of Cytochrome c Through Synergistic Site Replacements, S. Komar-Pauicucci, J. Bixler, G. Bakker, F. Sherman, and G. McLendon, J. Am. Chem. Soc. 1992, 114, 5443. 120. Electron Transfer in Bis-Porphyrin Donor-Acceptor Compounds with Polyphenylene Spacers Shows a Weak Distance Dependence, A. Helms, D. Heiler, and G. McLendon, J. Am. Chem. Soc. 1992, 114, 6227. 121. Electrochemical Probes of Protein Folding, J. Bixler, G. Bakker, and G. McLendon, J. Am. Chem. Soc. 1992, 114, 6938. 122. Increased Stability of Mutant Forms of Yeast Cytochrome c, D. R. Hickey, G. McLendon, and F. Sherman, in Stability of Protein Pharmaceuticals, Part B. In Vivo Pathways of Degradation and Strategies for Protein Stabilization. T. J. Ahern and M. C, Manning, (eds.), Plenum Press, New York, Chapt. 6., 1992, pp. 183-208. 123. Effects of Surface Amino Acid Replacements in Cytochrome c Peroxidase on Intracomplex Electron Transfer from Cytochrome c, A. F. Corin, R. A. Hake, G. McLendon, J. T. Hazzard, and G. Tollin, Biochemistry 1993, 32, 2756. 124. AgBr Photophysics from Optical Studies of Quantum Confined Crystals, A. P. Marchetti, K. P. Johansson, and G. L McLendon, Phys. Rev. B 1993, 47, 4268. 125. Thermodynamic and Kinetic Aspects of Binding and Recognition in the Cytochrome c/Cytochrome c Peroxidase Complex, G. McLendon, Q. Zhang, S. A. Wallin, R. M. Miller, V. Billstone, K. G. Spears, and B. M. Hoffman, J. Am. Chem. Soc. 1993, 115, 3665. 126. Electron Transfer and Energy Transfer in the Hb:Hb Reductase (cyt b5) System, J. Simmons, G. McLendon, and T. Qiao, J. Am. Chem. Soc. 1993, 115, 4889.
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127. Photoredox Chemistry of Metal Complexes in Microheterogeneous Media, R. Cowdery- Corvan, S. P. Spooner, G. L. McLendon, and D. G. Whitten, ACS Adv. Chem. Ser. 1993, 238, 261. 128. Electron Transfer Reactions at CdS Semiconductor Cluster Interfaces. Adsorption and Microenvironment Effects on Oxidative Reactions, J. R. Cowdery-Corvan, D. G. Whitten, and G. L. McLendon, Chem. Phys. 1993, 176, 377. 129. Electron Transfer from Cytochrome b5 to Met Hemoglobin, T. Qiao, D. Horn, J. Simmons, R, Chandler, and G. McLendon, J. Phys. Chem. 1993, 97, 13089. 130. Light-Emitting Porous Silicon After Standard Microelectronic Processing, C. Peng, L Tsybeskov, P. M. Fauchet, F. Seifert, S. K. Kurinec, J. M. Rehm, and G. McLendon, Mat. Res. Soc. Sym. Proc. 1993, 298, 179. 131. Comparative Photophysics of Direct and Indirect Band Gap Semiconductor Clusters, K. Johannson, R. Corvan, M.O'Neil, J. Rehm, A. Marchetti, D. G. Whitten, and G. McLendon, Isr. J. Chem. 1993, 33, 67. 132. Size Dependence of Radiative Rates in the Indirect Band Gap Material AgBr, W. Chen, G. McLendon. A. Marchetti, J. M. Rehm, M. I. Freedhoff, and C. Myers, J. Am. Chem. Soc. 1994, 116, 1585. 133. Structural Dynamics in an Electron-Transfer Complex, M.-F. Jeng, S. W. Englander, K. Pardue, J. Short Rogalskyj, and G. McLendon, Nature (Structural Biology) 1994, 1, 234. 134. The Role of a Conserved Internal Water Molecule and Its Associated Hydrogen Bond Network in Cytochrome c, A. M. Berghuis, J. G. Guillemette, G. McLendon, F. Sherman, M. Smith, and G. D. Brayer, J. Mol. Biol. 1994, 236, 786. 135. Ion Implantation of Porous Silicon, C. Peng, P. M. Fauchet, F. Seiferth, S. K. Kurinec, J. M. Rehm, and G. McLendon, Appl. Phys. Lett. 1994, 64, 1259. 136. "Gated" Electron Transfer in Hemoglobin and Hemoglobin Hybrids, J. Feitelson and G. McLendon in Methods in Enzymology, Vol. 232C, Academic Press, New York, 1994, pp. 86. 137. Prospects for Light-Emitting Diodes Made of Porous Silicon From the Blue to Beyond 1.5 µM, P. M. Fauchet, C. Peng, L. Tsybeskov, Ju. V. Vandyshev, A. Dobois, L. McLoud, S. P. Duttagupta. J. M. Rehm, G. L. McLendon, E. Ettedgui, Y. Gao, A. Raisanen, T. E. Orlowski, L. J. Brillson, and G. E. Carver, S.P.I.E. Proceedings 1994, 2144, 34. 138. Electron Transfer in Cytochrome c Depends upon the Structure of the Intervening Medium, T. B. Karpishin, M. W. Grinstaff, S. Komar-Panicucci, G. McLendon, and H. B. Gray, Structure 1994, 2, 415. 139. Themodynamics of the Equilibrium Unfolding of Oxidized and Reduced Saccharomyces cerevisiae Iso-1-Cytochromes c, S. Komar-Panicucci, D. Weis, G. Bakker, T. Qiao, F. Sherman, and G. McLendon, Biochemistry 1994, 33, 10556. 140. Reactivity of Alkanethiols Toward Gold Films Deposited on Silica and Mica, L. H. Guo, J. Facci, R. Moser and G. McLendon, Langmuir 1994, 10, 4588. 15
141. Intense Room Temperature Light Emission in Porous Silicon: From Less Than 450 nm to Beyond 1.5 µM, P. M. Fauchet, C, Peng, L. Tsbeshov, J. Vandyshev, A. Dubois, A. Raisanen, T. E. Orlowski, L. J. Brillson, J. E. Fouquet, S. L. Dexheimer, J. M. Rehm, G. L. McL.endon, E. Ettedgui, Y. Gao, F. Seiferth, and S. K. Kurinec, Proc. 7th Int. Sym. Silicon Mar. Sct. Tech. 1994, 10, 499. 142. Luminescence Properties of Indirect Bandgap Semiconductors: Nanocrystals of Silver Bromide, W. Chen, J. M. Rehm, C. Meyers, M. I. Freedhoff, A. Marchetti, and G. McLendon, Mol. Cryst. Liq. Cryst. 1994, 252, 79 (Proceedings 6th International Conference on Photophysics of Solids). 143. Direct Electrochemistry of Cytochrome c, H. A. O. Hill and G. McLendon, in Cvtochrome c Handbook, R. Scott and A. G. Mauk (eds.), 1994. 144. Photophysical Probes of a Protein/Semiconductor Electrode Interface, L.-H. Guo, S. Mukamel, and G. McLendon, J. Am. Chem. Soc. 1995, 117, 546. 145. The Zinc Coordination Site of the Bacteriophage Mu Translational Activator Protein. COM, R. T. Witkowski, S. Hattman, L. Newman, K. Clark, D. L. Tierney, J. Penner- Hahn, and G. McLendon, J. Mol. Biol. 1995, 247, 753. 146. Effect of Gold Topography and Surface Pretreatment on the Self-Assembly of Alkanethiol Monolayers, L.-H. Guo. J. S. Facci, G. McLendon, and R. Mosher, Langmuir 1995, 11, 4588. 147. Quantum Confinement Effects on 100-400 Å Diameter Silver Bromide Microcrystals, M. L. Freedhoff, G. McLendon, and A. Marchetti, Mat. Res. Soc. Symp. Proc. 1995, 358, 301. 148. Electron Transfer from Quantum Confined-States, M. O’Neil, G. McLendon, and A. Nozik in Surface Electron Transfer Processes, R. J. D. Miller (ed.), VCH Publishers, New York, 1995, pp. 311-364. 149. Stabilizing Amino Acid Replacements at Position 52 in Yeast Iso-1-cytochrome c: In Vivo and in Vitro Effects, L. I. Linske-O'Connell, F. Sherman, and G. McLendon, Biochemistry 1995, 34, 7094. 150. Site Specific Combinations of Stabilizing and Destabilizing Amino Acid Replacements in Yeast Cytochrome c: In Vivo and In Vitro Effects, L. I.. Linske-O'Connell, F. Sherman, and G. McLendon, Biochemistry 1995, 34, 7103. 151. Distance Dependence of Electron Transfer Rates in Bilayers of a Ferrocene Langmuir-Blodgett Monolayer and a Self-Assembled Monolayer on Gold, L.-H. Guo. J. S. Facci, and G. McLendon, J. Phys. Chem. 1995, 99, 8458. 152. Electron Transfer Processes in Metalloproteins, G. McLendon, in Handbook on Metal Ligand Interactions, Binoinorg. Chem. 1995, 1, 317. 153. Structural and Functional Effects of Multiple Mutations at Distal Sites in Cytochrome c, T. Lo, S. Komar-Panicucci, F. Sherman, G. McLendon, and G. Brayer, Biochemistry 1995, 34, 5259. 154. Investigation of Chemical Adsorbate Effects of Blue on Red Emitting Porous Silicon Samples, J. Rehm, G. McLendon, L. Tsybeskov, and P. Fauchet, MRS Soc. Sym. Proc. 1995, 358, 393. 16
155. How Methanol Affects the Surface of Blue and Red Emitting Porous Silicon, J. Rehm, G. McLendon, L. Tsybeskov, and P. Fauchet, Appl. Phys. Lett, 1995, 66, 3669. 156. Modulated Growth of Saccharomyces by Altexing the Driving Force of Cytochrome c: Does Marcus Theory Apply in vivo? S. Komar-Panicucci. F. Sherman, and G. McLendon, Biochemistry 1996, 35, 4878. 157. Luminescence Properties of AgBr: From Nanocrystals to Microcrystals, M. Freedhoff, J. Rehm, W. Chen, C. Meyers, A. Marchetti, and G. McLendon, NATO Adv. Studies Workshop, Reidel Press 1996, 3, 12, 281. 158. X-ray Photoemission Study of the Interface Formation Between Calcium and Self- Assembled Alkanethiol Monolayers, H. Razafitrimo, E. Ettedgui, Y. Gao, L.-H. Guo, and G. L. McLendon, Appl. Phys. Lett. 1995, 67, 2621. 159. Determining the Conduction Band and Valence Baud Shift of Porous Silicon Using Electron Transfer, J.M. Rehm, G.L. McLendon; P.M. Fauchet, Proc. Intl. Symp. Advanced Luminescent Materials 1995, The Electrochem. Soc., Pub., 1996, 212. 160. Kinetic Studies of the Hemoglobin: Hemoglobin Reductase (Cytochrome b5 ) Reaction, T. Qiao, R. T. Witkowski, and G. McLendon, J. Biol. Inorg. Chem. 1996, 1, 432. 161. Femtosecond Electron-Transfer Dynamics at a Sensitizing Dye-Semiconductor (TiO2), J. Rehm, G. McLendon, Y. Nagasawa, K. Yoshihara, L. Moser and M. Grätzel, J. Phys. Chem. 1996, 100, 9577. 162. Conduction and Valence Band Edges of Porous Silicon Determined by Electron Transfer, J. M. Rehm. P.M. Fauchet, and G.L. McLendon, J. Am. Chem. Soc. 1996, 118, 4490. 163. Optical Properties of Nanocrystalline Silver Halides, Michal Freedhoff, Alfred Marchetti. and George McLendon, J. Lumin. 1996, 70, 400. 164. Conformational Dependence of Electron Transfer Across De Novo Designed Metalloproteins, M. Mutz, E. Gaillard, J. Wishart, A. Corin, and G. McLendon, Proc. Natl. Acad. Sci. 1996, 93, 9521. 165. Photo-active and Electro-active Protein Films Prepared by Reconstitution with Metalloporphyrins Self-Assembled on Gold, L.H. Guo, G. McLendon, H. Razafitrimo and Y. Gao, J. Mater. Chem. 1996, 6, 369. 166. Unusual Temperature Dependence of Electron Transfer Rates in the Hemoglobin Reductase System, T. Qiao, R. Henderson, and G. McLendon, Inorg. Chim. Acta (special issue in honor of H.B. Gray) 1996, 242, 7. 167. Radiolysis and Photochemistry in the Study of Natural and Designed Redox Proteins, M. Mutz, J. Wishart, E. Gaillard, and G. McLendon, ACS Adv. Chem. Ser. 1997, 254. 168. Photoinduced Electron Transfer Between Ccp (D37K) and Zn Cc: Probing the Two Domain Binding and Reactivity of the Peroxidase, J. Zhou, S. Tran, G. McLendon, and B.M. Hoffman, J. Am. Chem. Soc. 1997 119, 269. 169. Mutagenesis of Yeast Cytochrome c1, S. Hatch and G. McLendon, Protein Science 1997, 6, 83. 17
170. Extragenic Compensation in Complex Formation: Restoration of Binding of a Charge Reversal Mutant of Cytochrome c Peroxidase (D217K) by a Compensatory Charge Reversal in Cytochrome c (K77D), R. Hake, A. Corin, G. McLendon, J. Am. Chem. Soc. 1997, 119, 10557. 171. A Protein Designed by Binary Patterning of Polar and Nonpolar Amino Acids Displays Native-like Properties, S. Roy, G. Ratnaswamy, J.A. Boice, R. Fairman, G. McLendon, and M. H. Hecht, J. Am. Chem. Soc. 1997, 119, 5302. 172. Optical Properties of Semiconductor Nanocrystals: Cu2O, A.P. Marchetti, M.I. Freedhoff, P, Rodney, G. McLendon, Mater. Sci. Forum 1997, 239, 679. 173. Optical Properties of Cuprous Oxide Nanocrystals, P.L Rodney, M.L Freedhoff, A.P. Marchetti, G.L. McLendon, and P.M. Fauchet, Mat. Res. Soc. Symp. Proc., 1997, 452, 383. 174. Nanoencapsulation of Cytochrome c and Horseradish Peroxidase at the Galleries of alpha-Zirconium Phosphate, C.V. Kumar and G. L. McLendon, Chem. Mater. 1997, 9, 863. 175. Equilibrium Metal Binding of the Translational Activating Protein, COM, R. T. Witkowski, G. Ratnaswamy, K. Larkin, G. McLendon, and Stanley Hattman, Inorg. Chem. 1998, 37, 3326. 176. Stereoselection in Designed Three-Helix Bundle Metalloproteins, M.A. Case, M. Reza Ghadiri, M. W. Mutz, G. L. McLendon, Chirality 1998 10, 35. 177. Metal and RNA Binding Properties of the hdm2 RING Finger Domain, Z. Lai, D. A. Freedman, A. Levine, G. McLendon, Biochemistry 1998, 7, No. 48, 17005-17015. 178. Thermodynamic and Structural Effects of a Single Backbone Hydrogen Bond Deletion in a Metal Assembled Helical Bundle Protein, J. Zhou, M. A. Case, J. F, Wishart, G. McLendon, J. Phys. Chem. B 1998, 102, 9975. 179. From Molecules to Materials: Current Trends and Future Directions. A.P. Alivisatos. P.F. Barbara, A.W. Castleman, J. Chang, D. A. Dixon, M. L. Klein, G. McLendon, J. S. Miller, M. A. Ratner, P.J. Rossky, S.I. Stupp, M.E. Thompson, Adv. Mater. 1998 10, 1297. 180. De Novo Design of Protein Function: Predictable Structure-Function.Relationships in Synthetic Redox Proteins, M. W. Mutz, M.A. Case, J. F. Wishart, M. Reza Ghadiri, G. L. McLendon, J. Am. Chem. Soc. 1999, 121, 858. 181. Monitoring Cysteine and Histidine Ligands in Zinc-Finger Peptides via Ultraviolet Resonance Raman Spectroscopy, M. Vargek, X. Zhao, Z. Lai, G. L. McLendon, and T. G. Sprio, Inorg. Chem. 1999, 38, 1372. 182. Stoichiometry, Free Energy and Kinetic Aspects of Cytochrome c: Apaf-1 Binding in Apoptosis, C. Purring, H. Zou, X. Wang, G. McLendon, J. Am. Chem. Soc. 1999, 121, 7435. 183. Metal Binding to the HIV Nucleocapsid Peptide, G. McLendon, H. Hull, K. Larkin, W. Chang, J. Biol. Inorg. Chem. 1999, 4, 171. 18
184. Applying Marcus' Theory to Electron Transfer In Vivo, G. McLendon, S. Komer- Panicucci and S. Hatch, Electron Transfer: From Isolated Molecules to Ciomolecules, Part Two, edited by Zoshua Jortner and M. Bixon, Adv. Chem. Phys. 1999, 107, 591. 185. Zinc-dependent protein folding, E. H. Cox, G. L. McLendon, Curr. Opin. Chem. Biol. 2000 4, 162-165. 186. Cytochrome b562 Variants: A Library for Examining Redox Potential Evolution, S. L. Springs, S. E. Bass, and G. L. McLendon, Biochemistry 2000, 7, 6075. 187. The Active Site Structure of Thalassiostra weissflogii Carbonic Anhydrase 1, E. H. Cox. G. L. McLendon, F. M. M. Morel, T. W. Lane, R. C. Prince, I. J. Pickering, and G. N. George, Biochemistry 2000, 39, 12128. 188. Cytochrome c Binding to Apaf-l: The Effects of dATP and Ionic Strength. C. Purring-Koch and G. McLendon, Proc. Natl. Acad. Sci. 2000, 97, 11928. 189. A Virtual Library Approach to Investigate Protein Folding and Internal Packing, M. A. Case, and G. L. McLendon, J. Am. Chem. Soc. 2000, 122, 8089. 190. Cytochrome b(562) Variants: A Library for Examining Redox Potential Evolution, S. L. Springs, S. E. Bass, G. L McLendon, J. Inorg. Biochem. 2001, 86, 73. 191. A Mutational Epitope for Cytochrome c Binding to the Apoptosis Protease Activation Factor-1 (Apaf-1), T. Yu, X. Wang, C. Purring-Koch, Y. Wei and G. L. McLendon, J. Biol. Chem. 2001, 276, 13034. 192. Disruption of Protein-Protein Interactions: Design of a Synthetic Receptor that Blocks the Binding of Cytochrome c to Cytochrome c Peroxidase, Y. Wei, G. L. McLendon, A. D. Hamilton, M. A. Case, C. B. Purring, Q. Lin, H. S. Park, C.-S. Lee, and T. Yu, Chem. Commun. 2001, 1581. 193. Carbon Monoxide Binding by de novo Heme Proteins Derived from a Designed Combinatorial Library, D. D. Moffet, M. A. Case, J. C. House, K. Vogel, R. Williams, T. G. Spiro, G. L. McLendon, M. H. Hecht, J. Am. Chem. Soc. 2001, 123, 2109. 194. A Multigeneration Analysis of Cytochrome b562 Redox Variants. Evolutionary Strategies for Modulating Redox Potential Revealed Using a Library Approach, S. L. Springs, S. E. Bass, G. Bowman, I. Nodehuau, C. E. Schutt and G. L. McLendon, Biochemistry 2002, 41, 4321. 195. Molecular Targeting of Inhibitor of Apoptosis Proteins Based on Small Molecule Mimics of Natural Binding Partners, R. A. Kipp, M. A. Case, A. D. Wist, C. M. Cresson, M. Carrell, E. Griner, A. Wiita, P. A. Albiniak, J. Chai, Y. Shi, M. F. Semmelhack, and G. L. McLendon, Biochemistry 2002, 41, 7344. 196. Additional IAP Binding Peptides and Assays for Identifying Compounds That Bind IAP, G. L. McLendon, R. A. Kipp, M. A. Case, and Y. Shi, U.S. Provisional Patent Application No. 60/395,918. Filed July 16, 2002. 197. The Kinetics of Translocation of Smac/DIABLO fom the Mitochondria to the Cytosol in HeLa Cells, S. L. Springs, V. M. Diavolitsis, J. Goodhouse, G. L. McLendon, J. Biol. Chem. 2002, 277, 45715. 19
198. Effect of redox potential of the heme on the peroxidase activity of cytochrome b562, S. Mazumdar, S. L. Springs, G. L. McLendon, Biophys. Chem, 2003, 105, 263. Special issue honoring Walter Kauzmann. 199. Do Main Chain Hydrogen Bonds Create Dominant Electron Transfer Pathways? An Investigation in Designed Proteins, Y. Zheng, M. A. Case, J. F. Wishart, and G. L. McLendon, J. Phys. Chem. B 2003, 107, 7288. Special Festschrift Issue honoring Professor Arnim Heaglein. 200. The Antiproliferative Action of Doxorubicin an a Novel Analog: Arrest of G1/S Transit Does not Result from Inhibition of eIF-5A Hydroxyation, H. M. Hanauske-Abel, E. C. Wolff, N. Hardegen, P. M. J. Clement, G. L. McLendon, A. R. Hanauske, B. M. Cracchiolo, M. H. Park, Clin. Cancer Res. 2003, 16, 6072C. 201. IAP-Binding Peptides and Peptidomimetics for Use in Diagnostic and Therapeutic Methods, George McLendon, U.S. Provisional Application No. 60/446,903, Filed February 12, 2003. 202. Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Analysis of Metal-Ion Selected Dynamic Protein Libraries, H. J. Cooper, M. A. Case, G. L. McLendon, and A. G. Marshall, J Am. Chem. Soc. 2003, 125, 5331. 203. Cytochrome c and the Suicide Hotline, G. L. McLendon, J. Inorg. Chem. 2003, 36, 206. 204. Two-dimensional Model for Peptide-Protein Binding, C. M. Cresson-Tarsa, F. H. Sillinger, S. Torquato, and G. L. McLendon, Biochem. 2003, 42, 8632. 205. Kinetic of Proton-Coupled Electron-Transfer Reactions to the Manganese-Oxo “Cubane” Complexes Containing the Mn4O46+ and Mn4O47+ Core Types, M. Maneiro, W. F. Ruettinger, E. Bourles, G. L. McLendon, G. C. Dismukes, Proc. Natl. Acad. Sci. 2003, 100, 3707. 206. Using Nanografting to Achieve Directed Assembly of De Novo Designed Metalloproteins on Gold, M. A. Case, G. L. McLendon, Y. Hu, T. K. Vanderlick, G. Scoles, Nano Lett. 2003, 3, 425. 207. Do Main Chain Hydrogen Bonds Create Dominant Electron Transfer Pathways? An Investigation in Designed Proteins, Y. J. Zheng, M. A. Case, J. F. Wishart, G. L. McLendon, J. Phys. Chem. B 2003, 107, 7288. 208. A High-Throughput Screen for Identification of Molecular Mimics of Smac/DIABLO Utilizing a Fluorescence Polarization Assay, C. J. Glover, K. Hite, R. DeLos, D. Scudiero, R. J. Fisher, M. J. Fivash, L. R. Smith, J.-W. Wu, Y. Shi, R. Kipp, G. McLendon, E. A. Sausville, and R Shoemaker, Anal. Biochem. 2003, 320, 157. 209. T-Jump Induced Helix to Coil Transition in GCN4 Derivative, A Model Coiled-Coil System: UV Raman Study, G. Balakrishnan, Y. Hu, M. A. Case, G. L. McLendon, Biophys. J. 2004, 86, 499A. 210. Mapping the Electron Transfer Interface Between Cytochrome b(5) and Cytochrome c, Y. Ren, W. H. Wang, Y. H. Wang, G. L. McLendon, Biochemistry 2004, 43, 3527.
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211. Design of a Functional Protein for Molecular Recognition: Specificity of Ligand Binding in a Metal-Assembled Protein Cavity Probed by F-19 NMR, A. J. Doerr, M. A. Case, I. Pelczer, G. L. McLendon, J. Am. Chem. Soc. 2004, 126, 4192. 212. Dynamics of Carbon Monoxide Binding to CooA, M. Puranik, S. B. Nielsen, H. Youn, A. N. Hvitved, J. L. Bourassa, M. A. Case, C. Tengrouth, G. Balakrishnan, M. V. Thorsteinsson, J. T. Groves, G. L. McLendon, G. P. Roberts J. S. Olson, T. G. Spiro, J. Biol. Chem. 2004, 279, 21096. 213. Hemoglobin Site-Mutants Reveal Dynamical Role of Interhelical H-Bonds in the Allosteric Pathway: Time-Resolved UV Resonance Raman Evidence for Intra-Dimer Coupling, G. Balakrishnan, C. H. Tsai, Q. Wu, M. A. Case, A. Pevsner, G. L. McLendon, C. Ho, T. G. Spiro, J. Mol. Biol. 2004, 340, 857. 214. Time-resolved Absorption and UV Resonance Raman Spectra Reveal Stepwise Formation of T Quaternary Contacts in the Allosteric Pathway of Hemoglobin, G. Balakrishnan, M. A. Case, A. Pevsner, G. L. McLendon, J. Mol. Biol. 2004, 340, 843. 215. Metal Assembled Modular Proteins. Towards Functional Protein Design, M. A. Case and G. L. McLendon, Acc. Chem. Res. 2004, 37, 754. 216. Design, Folding, and Activities of Metal-Assembled Coiled Coil Proteins, A. J. Doerr, G. L. McLendon, Inorg. Chem. 2004, 43, 7916. 217. Endonuclease-like Activity of Heme Proteins, W. B. Tan, W. H. Cheng, A. Webber, A. Bhambhani, M. R. Duff, C. V. Kumar, and G. L. McLendon, J. Biol. Inorg. Chem. 2005, 10, 790. 239. Tryptophan and Tyrosine to Terbium Fluorescence Resonance Energy Transfer as a Method to “Map” Aromatic Residues and Monitor Docking, J. E. Allen and G. L. McLendon, Biochem. Biophys. Res. Commun. 2006, 349, 1264. 242. Structure-activity Based Study of the Smac-binding Pocket within the BIR3 Domain of XIAP, A. D. Wist, L. Gu, S. J. Riedl, Y. Shi, and G. L. McLendon, Bioorg. Med. Chem. 2007, 15, 2935. 243. Biochemical Basis for Enhanced Binding of Peptide Dimers to X-Linked Inhibitor of Apoptosis Protein, K. E. Splan, J. E. Allen, and G. L. McLendon, Biochemistry 2007, 46, 11938. 244. Mutagenic Evidence for the Optimal Control of Evolutionary Dynamics, R. Chakrabarti, H. Rabitz, S. L. Springs, and G. L. McLendon, Phys. Rev. Lett. 2008, 100, 258103.
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