Glial cell line-derived nenrotrophic factor (GDNF ... - Springer Link

0 downloads 0 Views 994KB Size Report
ROBERTA VISCONTI~ GABRIELLA DE VITA, GELSY LUPOLI, MICHELE MARINACCIO, ALFREDO. FUSCO, MASSIMO SANTORO e GIANCARLO VECCHIO, ...
Rend. Fz}. Acc. Lincei s. 9, v. 8:t39-149 (1997)

Patologia.

activity.

--

G l i a l C e i l L i n e - D e r z v e d N e u r o t r o p h i c Factor ( G D N F )

stimulates Ret

N o t a di FRANCESCA CARLOMAGNO, ROSA MARINA MELILLO, GIULIANA SALVATORE,

ROBERTA VISCONTI~ GABRIELLA D E VITA, GELSY LUPOLI, MICHELE MARINACCIO, ALFREDO FUSCO, MASSIMO SANTORO e GIANCARLO VECCHIO,

presentata(*) dal Corrisp.

G.

Vecchio.

Aus'Iv,aCT. - - Ret is a receptor-like tyrosine kinase involved in several neoplastic and developmental diseases affecting thyroid gland and tissues of neuroectodermal origin. Rearrangements of the ret gene are observed in a sizeable fraction of human thyroid papillary carcinomas.