Health Informatics Morocco 2016 July 13-15, 2016 ...

Health Informatics Morocco 2016 EURO-MEDITERRANEAN MEDICAL INFORMATICS and TELEMEDICINE 2th Moroccan National Conference e-Health and Telemedicine in Mediterranean Countries

July 13-15, 2016 National School of Public Health (Rabat, Morocco)

Organized by National School of Public Health – ENSP The Polydisciplinary Faculty of Nador – FPN International Institute of TeleMedicine –IITM

With the Support of The US National Library of Medicine

in partnership with The Euromeditterranean Medical Informatics and Telemedicine Association - EMMIT American University of Leadership Morocco Foundation - AULM The Faculty of Medicine & Pharmacy of Fes - FMPF The Moroccan Society for Telemedicine & eHealth – MSfTeH The International Society for Telemedicine & eHealth – ISfTeH The Faculty of Sciences of Oujda – FSO Observatory for Communication & Audiovisual Med- OCCAM International Federation of Medical Students Associations Morocco – IFMSA Med ociation - Rabat ISCB-Regional Student Group Northern Africa Council – ISCB-RSG-NA Association of Moroccan Medical Doctors Abroad – C3M Moroccan Artificial Intelligence & Medtech Community – MAIMC

with the support of

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Table of Contents Messages from chairs of the MedInfo 2016 Conference .................................................... 3 Welcome address ............................................................................................................... 4 Introduction ......................................................................................................................... 5 Keynote speakers ............................................................................................................... 6 Programme ......................................................................................................................... 9 Oral presentations ............................................................................................................. 15 Special Session Presentations........................................................................................... 35 Committees........................................................................................................................ 40 Sponsors............................................................................................................................ 41 Partners.............................................................................................................................. 42

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EMMIT 2016 Conference Presentation Building on the successful First edition of the Mororccan National Medical Informatics and Tele-Medicine conference organized in 2013 in Nador, North of Moroccc, the aim of MedInfo 2016 held in Rabat, on July 2016 is to bring together once again experts from academia, public sectors, industry, national and global healthcare institutions such as WHO and ISfTeH, to stimulate research discussions, share experience with healthcare providers and policy makers. The 2nd Medical Informatics and Telemedicine event this year (MedInfo 2016) is organized by the School of Public Health and the Polydisciplinary Faculty of Nador and the International Institute of Tele-Medicine, in partnership with the EuroMediterranean Medical Informatics and Telemedicine association, with the support of many other partners including the International Society for Telemedicine & eHealth, The Moroccan Society for Telemedicine & eHealth, the faculty of Medicine of Fes, The American University of Leadership, the Moroccan Society of Medical Informatics, the Moroccan Doctors Juniors Associations, to name some. This conference edition will provide a forum to discuss achievements and current experiences in specific areas in medical informatics and telemedicine, focusing on innovation methods and approaches. Its overall goal is to increase interaction and collaboration among professionals from both health and Information & Communication technology sectors within and between the Mediterranean countries for scientific and social development in the Mare Nostrum. The Euro-Mediterranean Medical Informatics and Tele-Medicine conference series have been providing a forum for discussions and an environment that fosters creation of new collaboration in an interdisciplinary environment for a decade. They led to the emergence of the Euro-Mediterranean Medical Informatics and Telemedicine Association and number of regional cooperation. We hope that this year conference will accomplish the expectations announced in the recommendations of the previous ones, and will enhance collaboration between all participants coming from the Mediterranean, Europe, Africa and the Middle East. The organization of the MedInfo2016 Conference has come through the hard work of the local organizing committee, together with the International Institute of Tele-Medicine personnel and members of EuroMediterranean Medical Informatics and Tele-Medicine Association. The program was put together through the work of the scientific committee chaired by Prof. Francesco Sircurello. We are very grateful to all our sponsors, particularly to the US National Library of Medicine, the Moroccan National School of Public Health that accepted to host the event, and The Polydisciplinary Faculty of Nador. We are also excited about the list of participants who are coming in from the Mediterranean and around the world. Finally, we would like to add our welcome to all of you to the beautiful city of Rabat, the capital of Morocco, the Kingdom of peace and hospitality. Francesco Sicurello, Asmae Khattabi, Samia Chakri & Hassan Ghazal Chairs of the conference, http://www.msfteh.org/medinfo2016/

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Welcome address Dear Attendees, Welcome! On behalf of the organizing groups, namely the Euro-Mediterranean Association of Medical Informatics & Telemedicine, the International Institute of Medicine, The Polydisciplinary Faculty of Nador, The National School of Public Health, and the International Society for Telemedicine & eHealth, we are truly happy you have chosen to join us in Rabat for the 2nd eHealth and telemedicine Morocco conference, 2016. We are deeply grateful to the “The National School of Public Health” for hosting the conference and the satellite workshops, the National Library of Medicine for important financial support, to The Polydisciplinary Faculty of Nador for outstanding support and to all other partners for endorsement of this event. Over the course of the conference, you will have the pleasure of experiencing 4 keynotes, over 25 talks, and posters. This year’s scope includes a special focus on issues relevant to Mediterranean countries for their engagement in Telemedicine and ehealth. May you enjoy the next three days with exciting talks, contemporary science, and take full advantage of the ample networking opportunities. This year’s conference was organized under the leadership of the conference co-chairs Francesco Sicurello, Samia Chakri, Asmae Khattabi and Hassan Ghazal, together with the members of the Scientific and organizing Committees. Special thanks go to Prof. Belalia Abdelmounim Director of the National School of Public Health, Prof. Azdi Moussa Ali, Dean of the Polydisciplinary Faculty of Nador, Dr. Abaacrouch Mina and Pr. Nejjari Chakib, Former Directors of the National School of Public Health, who fully supported the organization of this edition. eHeath and Telemedicine conference series is dedicated to providing high quality meetings to the scientific community. We believe each individual on the organizing committee has helped advance this mission. We thank them and our sponsors for their commitment and devotion. Finally, the entire Moroccan Medical and Medical Informatics community has enthusiastically welcomed the guests to Rabat city and fully embraced what we are trying to achieve. We encourage you to extend your personal words of appreciation and recognition to both the hosts and participants, with special thanks to the organizers from other countries who have helped for the course of the last 2 months, to build the conference program and components. Together with our partners and sponsors, we encourage you to make the best of every learning & networking moment and of every part of the conference talks and discussions. An opportunity like this to share uptodate science in such a wonderful setting does not happen every day! Sincerely, Ghazal Hassan, Khattabi Asmae, Chakri Samia, Local chairs On behalf of local organizing committee, 11 July, 2016 Dear Conference Attendees, We welcome you to Rabat for the 2th conference on Telemedicine and Medical Informatics Morocco. To have this conference new edition in the mid-Summer and immediately after the holy month of Ramadan is testimony of the dedication of the Moroccan Scientific and Medical community. The Program Committee would like to express its gratitude to the local hosts for facilitating the organization. Over months, the Program and Scientific Committees have worked to process invitations for keynote speakers, to manage paper’ submission and evaluation, to organize the technical program, to prepare the material for the conference, among other things. This was a team of dedicated volunteers who accepted to take this responsibility, in addition to their already full agendas and busy personal lives. We would like to thank Kamal, Hayat, Kawtar, Saad, Salim, Imane, Laila, Soumya, Soad, Sahar, and Younes, to name some of the ones that were leading the hard work along with many other members of the community. Please forgive if we come to miss some names. On behalf of our societies and institutions, we say thank you to all of you. Francesco Sicurello, Program Chair, On behalf of the Program Committee 4

Introduction ICT in healthcare today encompasses not only administrative management of services but the management of the patient’s information during the process of treatment and care (in ambulatory, hospital ward and for disease prevention, rehabilitation, etc.). This is the field of Medical informatics, regarding in particular the management and treatment of data collected in many healthcare structures (medical records, clinical/epidemiological data bases, Hospital Information Systems, etc.). These data are important for administrative activities, clinical practices, for biomedical researches and studies in statistics and epidemiology. In last recent years many biomedical data sprang of the research on human genome and molecular biology (with the construction of vast and specific data banks), producing a new branch, the bioinformatics, rapidly evolving. A third branch, the neuroinformatics that is possible to relate to medical informatics, regards the brain cognitive processes. Today and in the future, thanks to the discoveries of the biomedical research and pharmacology, molecular biology and neurosciences these branches must and will cooperate together. Biomedical informatics is a new discipline due to the fact that now many projects are conducted at molecular and cellular level (effects of genomic and proteomic programs). This synergy between bio, neuro and medical informatics has an influence on electronic health records and on decision support system in medicine. Moreover the very speed exchange of data and information through the network permits to researchers and clinicians to have in short time the results of the biomedicine research ready to clinical treatments and care. By means the telecommunications systems based on advanced communication infrastructures that cover the entire Mediterranean area and others countries in the world, it is possible now to develop and install many telemedicine services. The Internet diffusion permits the access to specialist knowledge of excellence centres even from remote countries, in order to give patients the better cure. Moreover, the development of web sites and portals permits to put on line medical information, protocols, guidelines, useful to support the diagnostic/therapeutic processes of care and for the continued education in medicine. The remarkable developments of ICT and networks in health care generated a big revolution in healthcare organization and in the “doctor-patient” relationships. By means of new telemedicine systems it will be possible to do at distance many medical activities as tele-consulting, tele-diagnosis, tele-monitoring, tele-training, etc., in different fields of medicine (cardiology, radiology, dermatology, oncology, etc.). In this way it’s possible to diffuse the assistance and care to a large number of citizens/patients (in developed and developing countries) for prevention, treatment and care of diseases (acute and chronic due to the ageing of population). Prof. Francesco Sicurello Program Chair of MedInfo 2016 IITM – International Institute of Tele-Medicine University Technological Centre of Desio University of Milano Bicocca

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Keynote speakers

Francesco Sicurello Prof. Francesco Sicurello has Degree in Physics (Electronics and Cybernetics), with many years of experience (from 1978) in Medical Informatics, Telemedicine, e-Health and statistical software for data analysis in epidemiology and biomedicine. He is president of IITM (International Institute of Tele-Medicine) / Italian Association of Telemedicine and Medical Informatics (@ITIM). From 1999 till now he is professor of Medical Informatics and Telemedicine at University of Milan-Bicocca. From 2007 to 2012 professor of Ontology and its applications at University of Insubria (Como). From 1996 to 1999 professor of Electronic Documents at University of Macerata. From 1984 to 2001 professor of Informatics applied in Medicine and Statistical Software at University of Milan. From 2004 to 2014 he had been Coordinator of Technological University Centre of Desio (MB). Since 2000 to 2012, he was referent for Telemedicine in the Scientific and Technological Cooperation of Italian Ministry of Foreign Affairs. He was expert in health informatics and head of operating unit (2001-2008) at the Health General Directorate (Research and Innovation Office) of Lombardia Region. For about 10 years (1990-1999) he had been Head of a Research Operating Unit of Medical Informatics at Institute of Biomedical Technologies at National Council of Research in Milan. For 5 years (1996-2000) he was director of Informatics Service at National Institute of Neurology in Milan. He also worked as responsible of medical informatics and data analysis in hospitals as Policlinic of Milan, Desio Hospital. From 1978 to 1986 he was designer, developer and responsible at Desio Hospital of epidemiological medical information system in the frame of the health and epidemiologic surveillance program of population involved in the dioxin environment disaster in the Seveso city area (at north of Milan). His activity consists on studies and designs of Health/Hospital Information Systems, computerization of medical record and clinical database, statistical software applications and artificial intelligence techniques in biomedicine (expert systems, artificial neural networks, etc.), Telemedicine systems, telecare services, web sites and portals in medical applications. He is responsible of several research projects on Medical Informatics and Telemedicine, involved in Italian, European and International R&D Programmes. He is author of around 400 publications (national and international) in Medical Informatics, Telemedicine and software for data analysis and mining, artificial neural networks, Neuroinformatics and Artificial Intelligence, knowledge management and ontology.

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Peter Tonellato Prof. Peter Tonellato earned his Phd in applied mathematics from the University of Arizona following study at both the University of Oxford and Hiroshima University. Past positions include Founding Director, Bioinformatics Research Center, Medical College of Wisconsin and Founder and CEO, of Pointone Systems, LLC, the first personalized medicine software company that provided genetic enabled ‘best practice’ clinical decision support systems to hospitals and health care facilities. Previous work includes the creation of the Rat Genome Database (rgd.mcw.edu), the first disease-centric repository of phenotype and genetic data and the Program in Genomic Applications (pga.mcw.edu) data mining system for a heterogeneous collection of phenotypes, microarray expression and genotypes. Currently, Professor Tonellato has joint appointment with Harvard Medical School as director of the Laboratory for Personalized Medicine (LPM) in the Department of Biomedical Informatics (lpm.hms.harvard.edu) and the Zilber School of Public Health, University of Wisconsin, Milwaukee where he directs the Laboratory for Public Health Informatics and Genomics (LPHIG) and Professor of Computer Science in the College of Engineering and Applied Science and of Health Informatics in the College of Health Sciences. Dr. Tonellato and his labs develop strategies, methods, bioinformatic tools, and analyses to study and test the accuracy and clinical efficacy of genetic discoveries and accelerate their translation to practical clinical use. LPM and LPHIG design and executeinsilico experiments to explore and solve barriers to translation from discovery to clinical use to public health.

Abdarrahman Annea Mr. Abdarrahman Anne is a librarian and lecturer at the Faculty of Medecine, University of Science of Science and Technology. He received a Master degree in Libranship from the Belorussian Univesity of Culture, Minsk(Belorussia) in 1994 and a Master Degre in Information Sciences from the Ecole Nationale Superieure des Sciences de l’Information et des Bibliotheques (Villeurbanne, France) in 2003. Passionate about Open Source and Free Software, he holds Linux Professional Institute Certification Level I (LPIC 1).He has worked as system librarian in charge of databases and ICT related matters at the library of the Faculty of Medicine, in Bamako for 10 years. In 2006-2007 he spent one year as a Associate Fellow at the National Library of Medicine (Bethesda, USA). He gave many trainings in information retrieval, library automation, free software and Linux system administration.

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Najeeb Al-Shorbaji Dr Najeeb AL SHORBAJI isVice-President for Knowledge, Research and Ethics eMarefa (www.e-marefa.net), Amman, Jordan Former Director of Department of Knowledge Management and Sharing, World Health Organization (WHO) Has been working as Director, Department of Knowledge Management and Sharing at the World Health Organization Headquarters (WHO/HQ) in Geneva since September 2008 till 2015. Prior to that he held the posts of Information Scientist, Regional Advisor for Health Information Management and Telecommunication and Coordinator for Knowledge Management and Sharing at the WHO Eastern Mediterranean Regional Office since February 1988. He is from Jordan, and holds a PhD in Information Sciences since 1986. Dr Al-Shorbaji’s portfolio covered WHO publishing activities and programmes, library and information services, knowledge networks, eHealth, knowledge translation and WHO Collaborating Centres. Through his career in WHO, he initiated and lead a number of information and telecommunication technology projects and knowledge networks. He is a member of a number national and international professional societies and associations specialised in information management and health informatics. He has authored over 80 research papers and articles presented in various conferences and published in professional journals.

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TECHCNICAL PROGRAM Wednesday, July 13 08.30 Welcome AND REGISTRATION 10.30 Opening Ceremony (Chairs : Dr. Asmae Khattabi /Pr. Hassan Ghazal) Drs. Asmae Khattabi/Hassan Ghazal, School Public Health/Polydisciplinary Faculty Nador Prof. Francesco Sicurello, President of the Conference, International Institute of Telemedicine Prof. Abdelmounim Belalia, Director of the National School of Public Health Rabat Prof. Ali Azdi Moussa, Dean of the Pluridisciplinary Faculty of Nador Dr. Dan Gerendasy, Chief officer, International Cooperation of NLM Prof. Rajae Cherkaoui, Vice President, University Mohammed V, Rabat Mrs. Samia Chakri, Director, Department eGov, Ministry of Industry, Trade, Investment and Digital Economy Prof. Chakib Nejjari, Dean of the School of Public Health, University Mohammed VI (UMVI), Casablanca ( Prof. Mohammed El Azami Elidrissi, Vice Dean of the Faculty of Medicine of Fes Dr. Anas Lahlou, President of the American University of Leadership Morocco Foundation (AULMF) Prof. Senoussi Mohamed, Vice President of AULMF Arch. Pierapolo Saporito, President of OCCAM – UN affiliated Prof.Ouldim Karim, General Secretary, Moroccan Society of Medical Genetics, UMVI, Casablanca Dr.Hanae Cherradi, Vice-President of the Moroccan Society of Telemedicine and eHealth Prof. Mohammed Bennani Othmani, President of the Moroccan Society of Medical Informatics Dr. Samir Kaddar, President of the Association of Moroccan Physicians Abroad (C3M), Belgium Mr. Abderrahman El Kafil, GNU Health Solidario representative for Mena region Mr. Abderrahman Anne, The Network of African Medical Librarians, University of Bamako, Mali Dr. Ousmane Ly, General Director, National Agency for Telehealth and Medical Informatics, Ministry of Health, Mali 9

Ms Alžběta Tylová, National Officer Reseach Exchange, IFMSACzech, Faculty of Medicine Prague Ms. Kaouthar Slimani, Moroccan Artificial Intelligence &

MedTech Community

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Mr. Saad Chaabi, President, Doctors Juniors Association (Med’ociation) Mr. Salim Hjiaj, President, International Federation of Medical Students (IFMSA)-Morocco Dr. Souilmi Yassine, International Society for Computational Biology (ISCB), International Student Council – Vice Chair for Africa Ms. Allali Imane, ISCB Student council, Regional Student GroupNorth Africa , President Mr. Omar Cherkaoui, President, IFMSA, MD candidate, Faculty of Medicine of Rabat Prof. Peter Tonellato, Director, Lab for Personalized Medicine, Harvard Medical School, USA Special Session with Keynote speakers Francesco Sicurello (President of IITM, University of MilanoBicocca, Italy) Peter Tonellato M. (Harvard Medical School, Boston, MA, US) Lunch

Wednesday, July 13 SESSION I: MEDICAL DATA BASES AND HEALTH INFORMATION SYSTEMS (CHAIRS: M. BENNANI/ S. NASSIRI)

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1) Le rôle important du LIMS (Laboratory Information management System) pour l'innovation biotechnologique Abdelaali BRIACHE 2) Information system for the registration and the management of the familial colorectal cancer Soukaïna AZOUGH 3) Important Success criteria and factors to integrate an Information System for envenomed patients Adil Echchelh 4) Modeling of actions to take when a patient is envenomed by developing a web based information system Abdelmajid Soulaymani 5) The availability and security aspects by an e-health Information system. Abdelghani El Malhi 6) Les référentiels sémantiques dans l'interopérabilité des systèmes d'information de santé Manar Jallal 7) Exchanging medical information between distributed hospital information systems Sanae Mazouz

16.00 Coffee Break SESSION II: INTELLIGENT SYSTEMS AND E-HEALTH (CHAIRS: F. SICURELLO/S.CHAKRI) 16.30 8) A new method for estimating the space filling of the human lung Kaoutar Lamrini Ouahabi 9) ToxiFlow: A system of collection, storage and exploitation of data Safae Nassiri 10) One health approach: Decision support system for surveillance of West Nile Virus in the Mediterranean Basin Patrizia Colangeli 11) Integrated scheme for modelling the operating procedures of clinical and environmental Analysis at the National Institute of Hygiene of Morocco Chaqsare Souad 12) The zoonoses data collection in Italy: an expert system for data quality management and improvement Patrizia Colangeli

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13) Application of a mobile platform for instant messaging, classification and transfer of medical data among doctors for faster medical diagnosis Kauthar S Usop 14) Informatisation des centres de transfusion : expérience de Rabat Khadija .Hajjout

Thursday, July 14 SESSION III: TELEMEDICINE AND MOBILE HEALTH (CHAIRS: H. GHAZAL/Patrizia Colangeli) Keynote : Francesco Sicurello: Trends in eHealth and telemedicine 09.00 15) Promoting Population Health Through mHealth: Can Personal Health Management System Alter Personal Health Behavior?” Adam Bouras 16) Mobile Health Apps for people with mental and physical disabilities in Morocco Hayat Sedrati 17) Application of a Mobile Telemedicine Decision Support System for Psychiatric Data Acquisition of Mental Health Care Patients Kauthar S. Usop 18) La Maîtrise Statistique du Processus et analyse du Temps d’Attente des patients au Service d’Admissions et des Urgences Naima Ait Mouddene 10.30 Coffee Break SESSION IV: DEVICES, TELEMONITORING, AND E-CARE (CHAIRS: K. OULDIM/ K. SLIMANI) 11.00 19) ECG signal de-noising using Wavelet Transform Nada Beili 20) Telecardiology: Democratizing access to cardiac care S. Mouram 21) Contribution of ultrasound robotic arm tele-operated during interventional procedure Ayoub Jean 22) Contribution of robotic arm tele-operated during interventional procedure of ablation Sahar Mouram

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23) Awareness of Nurses Towards Information Communication (TeleNursing) in Patient Care in Federal Teaching Hospital IdoEkiti, Ekiti State Nigeria Paul I. Sunmbola 24) Setting up an information system for a newborn screening program Souad Chaqsare

12.30 LUNCH SESSION V: BIOINFORMATICS, MODELLING AND DATA MINING (CHAIRS: M. EL AZAMI EL IDRISSI/ R. ALAMI) Keynote : From Personalized Medicine to Precision Medicine and Precision Public health : Prof. Peter Tonellato 14.00 25) Medical Genomics Big Data Challenges Yassine Souilmi 26) Metagenomics analysis of The Moroccan Human Gut Microbiome Imane Allali 27) Revealing the Microbial diversity of the Moroccan Marine ecosystems using Bioinformatics tools Bouchra Chaouni 28) Laboratory Information Management System adapted to support genomic and metagenomic analysis for diagnosis Patrizia Colangeli, 15.30 Coffee Break SPECIAL SESSION: TELEMEDICINE IN MEDITERRANEAN COUNTRIES Chairs: Pierpaolo Saporito / Asmae Khattabi 16.00 Telemedicine in Mediterranean Countries Francesco Sicurello 16:30 Moroccan Digital egov strategy for Health Samia Chakri 17:00 Telemedicine in Morocco Hassan Ghazal 17:15 Telemedicine in Mena region Najeeb Shorbaji 17:30 Medical Informatics in Morocco Mohammed Bennani 17:45 Telemedicine in Mali Ousmane Ly 18:15 eMedMed project 13

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Pierpaolo Saporito General Discussion: Building a Mediterranean Telemedicine Network SOCIAL DINNER

Friday, July 15 SESSION VI : (CHAIRS: H. GHAZAL/S. CHAQSAR) 09.00 GNU HEALTH Mr. El Kafil Abderrahman 10.30 Coffee break SESSION VII: SPECIAL KEYNOTE SPEAKERS SESSION (CHAIR: F. GABOUN/N.BENTALEB) 11.00 Peter Tonellato: Big data in Public Health 11.30 Francesco Sicurello: Neuroinformatics and tele-rehabilitation 12.00 General Discussion and Recommendations 12.45

Closing Remarks

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Oral Presentations

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(1) Le rôle important du LIMS (Laboratory Information management System) pour l'innovation bio technologique Houda SEKKA, Abdelaali BRIACHE SPLIMS Maghreb-LabVantage Group, Address: 07, Rue Mortada, Quartier Palmier, Casablanca. Maroc. Corresponding author: [email protected] Les laboratoires sont des structures qui gèrent et génèrent des données multiples et de différents genres. Leurs activités sont assurées par des processus strictement régis par des normes et des pratiques connues dans le domaine. Le LIMS Labvantage (Laboratory Information management System) est un système qui permet entre-autres de: 1. Modéliser et automatiser les workflows et les processus de travail par une interface utilisateur graphique intuitive, 2.gerer et tracer toutes les informations des laboratoires : projets, études, tâches microplaques, réactifs, composants etc., 3. Saisir intuitivement les données à partir de terminaux ou application tierce. 4. Fonctionner en conformité Avec les normes Internationales. Notre intervention sera une occasion pour survoler et introduire le LIMS Labvantage. Nous nous focaliserons spécialement sur les principales fonctionnalités qui permettent de gérer les flux important des laboratoires. Keywords : Laboratory Information management System, LIMS Labvantage (2) Information system for the registration and the management of the familial colorectal cancer (1)

Soukaïna AZOUGH, (2)Noufaika ABOUBACAR, (1,3)El Bachir BENJELLOUN, (2)Ahmed AZOUGH (1) Faculty of Medicine and Pharmacy of Fes (FMPF), (2)Faculty of Sciences Dhar El Mahraz (FSDM), (3) HassanII university hospital Corresponding author: [email protected] The familial colorectal cancer is a complex medical issue. It requires special care and attention not only to the patient, but also to his relatives who are individuals at high risk of developing the cancer. This requires the development and maintenance of registries that leads to better outcomes in the screening and the follow up of these individuals. The project consists of a web based information system for the management of a familial colorectal cancer hospital registry. It allows the registration of the families, the establishment of the pedigrees, the registration of the individuals at risk, and the storage of their medical and non-medical information in the aim of organizing the follow up. The software has been conceived and developed under collaboration between the Faculty of Medicine and Pharmacy of Fes (FMPF) and the Computer Science Department of the Faculty of Sciences Dhar El Mahraz Fes (FSDM). Keywords: Familial colorectal cancer, Information system, Registry (3) Important Success criteria and factors to integrate an Information System for envenomed patients Adil Echchelh, Mohamed Ahd, Abdelghani El Malhi, Abdelrhani Mokhtari, Rachida Soulaymani Bencheikh, Abdelmajid Soulaymani Laboratory of electrical engineering and energetic systems, Laboratory of Genetics and Biometry, Faculty of Sciences, Ibn Tofail University BOX13, 14000, Kenitra, Morocco Corresponding author: [email protected] In Morocco, all data related to poisoning or envenomation are elaborated in reports and sheets by the CAPM. Patient’s information are sensitive and needs to be handled with precaution. Storing, treating and analyzing millions of gathered records is critical for the health authorities in order to define the adequate and efficient strategy to battle against this phenomenon. In this work, we propose the

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deployment of a web based centralized information system. The approaches that are being used since a long time are not enough productive and shows many rooms of improvement. E-Health technologies often face adoption and exploitation problems as the return on investment is not thoroughly understandable. The more the data is organized, the easier can be explored. The developed system is able to provide the health professionals with the following fundamentals features: the measurement, the monitoring, the guidance, the data management and their analysis. As the uptake of new technologies in the health sector is still poor and very limited, one of the main objective of this communication is to highlight the benefit and the priority of introducing such tools by advocating a reliable information system. To this end, we determined first the important criteria and factors for Information Systems Integration Success. Then we present the main functionalities offered by the application. Concretely the objective is to obtain a customized data model in order to centralize the information of envenomed patients and then to help building the needed dashboards and the best practices in the treatment. Keywords: E-Health, data model, system information, vital signs, envenomation, data extraction (4) Modeling of actions to take when a patient is envenomed by developing a web based information system Abdelmajid Soulaymani, Abdelghani El Malhi, Adil Echchelh, Abdelrhani Mokhtari, Rachida Soulaymani Bencheikh. Laboratory of Genetics and Biometry, Laboratory of electrical engineering and energetic systems, Faculty of Sciences, Ibn Tofail University BOX13, 14000, Kenitra, Morocco Corresponding author: [email protected] Based on a long experience and collected information about envenomation, Anti Poison and Pharmacovigilance Center of Morocco (CAPM) developed a guideline with clear actions to help both the patients and the health professionals. The application of information technology in health sector has grown exponentially over the last years. The tool will classify the victims based on the value of their vital signs and the Glasgow score. This helps to treat and handle the envenomation competently. This research aimed to model a health care system and make it easier to use by the professionals. It will allow the clinician to monitor the evolution of the different vital signs and eventually suggest the best hospitalization (type of drug, reanimation, release….). The main objective is to improve the effectiveness and the efficiency. The developed application contains sensible data, therefore the general concept is constructed to be secure. Furthermore, it is web oriented, which should facilitate the communication between the various sanitaire structures. The program helps to gather some important statistics and analysis. Keywords: Modeling, Anti Poison Centre, scorpion sting, vital signs, eHealth, information system. (5) The availability and security aspects by an e-health Information system Abdelghani El Malhi, Adil Echchelh, Mohamed Ahd, Abdelrhani Mokhtari, Rachida Soulaymani Bencheikh, Abdelmajid Soulaymani. Laboratory of electrical engineering and energetic systems, Laboratory of Genetics and Biometry, Faculty of Sciences, Ibn Tofail University BOX13, 14000, Kenitra, Morocco Corresponding author: [email protected] Human, organization and technology are the essential components of an e-heath Information System. It contains certainly sensitive data and therefore the need to ensure the high level of security is very high. The achievement to have a networked server platform can help enormously the health care professionals to measure and monitor the daily progress. To guarantee the maximum security a restricted and limited entrance is indispensable; it can be implemented in both layers physical and logical. This work aimed to build a secured concept to handle the vital sings of envenomed patients. As the system availability is critical, we defined three fundamentals strategies: Replication, Backup 17

and Restoration. They allow the users to connect constantly without interruption. After any eventual system failure or a disaster, the SI can be restored from the most recent backup to avoid losing data. High availability is a characteristic of an application, which targets the insurance of an agreed level of operational performance. Keywords: availability, e-health, Information System, system security, backup, restoration. (6) Les référentiels sémantiques dans l'interopérabilité des systèmes d'information de santé Manar Jallal, Mouna Bouhaji, Naima Ait Mouddene, Samy Housbane, Zineb Serhier, Mohammed Bennani Othmani Laboratoire d’Informatique Médicale, Faculté de Médecine et de Pharmacie de Casablanca - CHU Ibn Rochd Casablanca, Maroc, Corresponding author: [email protected] Les systèmes d’information dans le domaine sanitaire doivent être communicants pour favoriser la coopération des professionnels dans le cadre du parcours de santé centré sur le patient, et pour aider à la décision médicale. Ainsi, la communication par des outils informatiques et la constitution de dossiers de patient informatisés demandent l’usage de référentiels sémantiques dont le pilotage est nécessaire. En effet, le principe du partage des données du patient s’impose en raison notamment du développement des connaissances médicales qui contribue à segmenter les savoir-faire, les compétences et les rôles des acteurs. L’application de ce principe permet une coordination renforcée entre les professionnels et demande des systèmes d’information adaptés et évolutifs. Le nécessaire partage des données et l’évolution des périmètres des systèmes d’information posent avec force la question de l’interopérabilité sémantique des systèmes de santé et de la gestion des référentiels. Mais si, dans le cadre de l’’interopérabilité des systèmes d’information, le choix, la maintenance et l’usage des référentiels sémantiques sont des conditions nécessaires, le comportement des acteurs et les modalités d’évaluation des pratiques restent néanmoins des composantes centrales du bon fonctionnement. L’objectif de notre travail est de traiter l’usage des terminologies de référence dans le domaine médical et décrire leur rôle dans l'interopérabilité des systèmes d’information de santé. Keywords : Interopérabilité sémantique ; Système d’Information de Santé ; Terminologie de référence (7) Exchanging medical information between distributed hospital information systems Sanae Mazouz, Ouçamah Mohammed Cherkaoui Malki Department of Computer Science, Faculty of Science Dhar El Mahraz, Fez, Morocco Corresponding author: [email protected] Exchanging and sharing medical information between hospital information systems (HIS) is a prevailing problem. The difficulty of this exchange is due to patient mobility and the presence of a large number of hospital information systems. Therefore, medical data are represented in heterogeneous formats that need to be integrated to build interoperate applications. Interoperability, independently of platforms, aims to ensure cooperation, communication and sharing information and services among several applications. In order to achieve semantic interoperability between distributed and heterogeneous hospital information systems, we propose the use of schema matching technique. For that, we created a semiautomatic schema matching tool, especially designed for the medical field, that aims to find semantic similarity between healthcare documents. This tool led to exchange medical information between distributed hospital information systems without requiring any technical training or making adjustments of the structure of these systems. Keywords: Distributed systems; Hospital information systems; Schema matching; Interoperability.

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(8) A new method for estimating the space filling of the human lung Kaoutar LAMRINI UAHABI, Mohamed ATOUNTI Laboratory of Applied Mathematics and Information Systems, Department of Mathematics and Computer Science, Multidisciplinary Faculty of Nador, University Mohammed First, 62702 Selouane, Nador, Morocco. Corresponding author: [email protected], [email protected] The human body is packed with a multitude of very complex structures. It’s the case for example of the respiratory system and the prodigious tracheal branching. A precise approach to these phenomena necessarily involves a mathematical modeling. Euclidean geometry is unfortunately powerless to resolve such problems. This geometry is largely interested in the smooth sets to which the methods of classical analysis can be applied. These forms have an integer dimension. Sets that are not sufficiently smooth or regular have tended to be ignored. Currently, this attitude has changed. It has been realized that the mathematics of non-smooth sets is very important. Moreover, irregular sets offer a much better presentation of many natural phenomena than do the figures of classical geometry. This is exactly where the fractal geometry intervenes, treating irregular and broken objects, called “fractals”. These fractals have a fractional dimension, which measures the space filling of an object. The fractal geometry is a revolutionary area of mathematics that has profound impact on every branch of science including the various fields of medicine. Biological systems are predominantly irregular, complex and non-linear. Irregularities of biological system cannot be quantified by means of classical Euclidean geometry. Therefore, the fractal geometry presents an ideal tool for a study of some problems of health. The non-linear concept of fractals, introduced and developed over the last decade, provides insights into the organization of complex structures such as the bronchial tree and heart, as well as into the dynamics of healthy physiological variability. In fact, the pulmonary system is a real fractal object. Then, it will be possible to use a modeling via the fractal analysis. About our work, we came by a technique of precise mathematical modeling, to obtain a new value of fractal dimension of the human lung. Moreover, the major axis of our investigation in this research is to have a unique value of this dimension that would be, hopefully, a reference value in the medical field, specifically in the physiology and pulmonary pathology. Keywords: Fractal dimension, pulmonary system, mathematical modeling, lungs, space filling, gas exchange surface. (9) ToxiFlow: A system of collection, storage and exploitation of data Safae Nassiri, Rachida Soulaymani Benchikh Centre Antipoison et de Pharmacovigilance du Maroc- Centre Collaborateur de l’OMS Corresponding author: [email protected] Within the framework of integration of its information system of the sanitary vigilances (Plants, Drugs, Food, Pesticides, Industrial Products, venomous animals, Gases, Household products, etc), the “Centre Antipoison et de Pharmacovigilance du Maroc” (CAPM) proceeded to a modernization of the information system, in an objective of improvement of the quality of the data and the information sharing between the internal departments and the opening towards the outside. In fact, the fast and reliable reporting of the poisonings is an important task for healthcare professionals. ToxiFlow is a system conceived by CAPM to meet the requirements reporting of the poisonings. It’s a system of storage, treatment and exploitation of the data. It’s intended to facilitate the data collection, creating a report of follow-up, and producing a national database on the poisonings, put at the disposal of the specialists to produce information susceptible to prevent the future events. Furthermore, ToxiFlow allows to obtain comparable statistics of activity, to have a shared, reliable and not redundant information 24 hours a day and 7 days a week, to develop common reference tables associating whenever possible a code stemming from an international nomenclature, to have a system

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of production of monitoring indicators, and to share the data between the various levels of responsibility. Keywords: Information system, Sanitary vigilances, Poisoning Reporting, Monitoring indicators, Statistics, Poison Control Center of Morocco (10) One health approach: Decision support system for surveillance of West Nile Virus in the Mediterranean Basin Savini L.(1), Tora S.(1), Di Lorenzo A.(1), Cioci D.(1), Colangeli P. (1), Calistri P.(1), Conte A.(1) 1 Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise “G. Caporale”, Campo Boario, Teramo, Italy, Corresponding author: [email protected] Introduction West Nile Virus (WNV) is a mosquito-borne flavivirus that sporadically causes local outbreaks in humans and horses in Africa, Europe, and Asia. The virus did not receive much attention until it was detected in New York in 1999, after which it rapidly spread across the North American continent and the Caribbean, causing human, equine, and avian infections and deaths. In August 2008 WNV infection re-emerged in northern Italy, spreading through the territories of three regions. Clinical signs of meningo-encephalitis were observed in horses and humans living in the infected area. In the following years new epidemics re-emerged in the same area, but new foci of infection were observed in central and southern Italy. Climate and local environmental conditions are likely to have a large impact on vector-borne diseases, as survival and development rates of ectothermic animals like ticks and insects are highly sensitive to these factors.Since 2010 WNV infection has become a public health in Europe: it has been responsible for an increasing number of epidemic outbreaks in European countries and in neighbouring countries in the Mediterranean basin. Tools to help predicting the risk of outbreak of vector-borne diseases within our changing Mediterranean environment are therefore needed. Materials and Methods The Geographical Information System is composed by Oracle 10g Database Management System and ESRI ArcGIS Server 10.3.1; the web mapping client application has been developed with the ArcGIS Server API for Javascript to facilitate and optimize the mash-up approach. ESRI ArcSDE 10.1 has been used to store spatial data and the Spatial Reference System used is WGS84. Results A GIS-based Information System has been developed, as a tool for: i) disseminating and sharing data analysis by web - the system displays the WNV distribution in the Mediterranean area and allows to search specific data of interest using a set of data filters (ie. date from-to, species, lineage, etc.), ii) helping in an spatio-temporal and epidemiological analysis – the system allows to visualize and download environmental and climatic data (ie. MODIS land surface temperature, vegetation indices) and provide tools like Graphs, Maps and tables to data visualization, management and reports. The system is able to handle multiple vector-borne diseases. Conclusions The System will be used to store the new WNV surveillance plane data for Italy and manage animal and human cases simultaneously. The next step will be to link each outbreak or positivity to his phylogenetic information, which helps epidemiologists to identify the origin of an outbreak or a cluster of diffusion. This relationship will allow a better understanding of the spatiotemporal spread of the virus strains in the Mediterranean Basin. References • Calistri P., Savini L., Ippoliti C. & Conte A., (2007), Web-based geographic information system tools and international surveillance network for bluetongue in the Balkans and south-east Europe (East-BTNet). Vet. It 43 (3), 739 – 744.

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Savini L., Ippoliti C., Conte A., Pelini S., Cerella A., Cioci D., Col angeli P., Brouw A., Calistri P. & Lelli R., 2008. EU-BTNET: a web-GIS for the surveillance of Bluetongue in Europe. Bluetongue Satellite Symposium. Bluetongue in Europe Brescia, Italy, 07/06/2008. Keywords: data collection, WNV, web-GIS, disease distribution, vector-born disease, disease surveillance, analysis tool (11) Integrated scheme for modelling the operating procedures of clinical and environmental Analysis at the National Institute of Hygiene of Morocco Chaqsare Souad1, Elkasmi Sahar1, Akil Elmahfoud1, Ben Aakame Rachid1, Benbouchta Yahya1, El Ouardi Abdelmoula1, Essouri Salah1, Khalil Najat1, Saouifi Mohammed1, Adlaoui El Bachir 1, Seghrouchni Fouad1 1 National Institute of Hygiene, Rabat, Morocco, Corresponding author: [email protected] The digital revolution engendered by technological changes, led the clinical and environmental laboratories to implement new methods and tools of computerization and digitization of all their processes. Along with this digital revolution, the development of biotechnology also generates more new techniques that, because of their better performance, quickly find their place in the practice of clinical and environmental biology. However, to increase the performance and organization levels of these laboratories, the processes setting of these technological tools must always be accompanied by the commitment to the quality standards policies. Furthermore, national level health institutions are generally providing services requiring different disciplines of clinical and environmental biology. Thus, Laboratory information management systems (LIMS) designed for such structures must then manage procedures of different natures and complexities. Therefore, modeling the analytical processes in this context must be done with a view to standardization and uniformity. The objective of this work is to propose an integrated scheme for modeling the operating procedures of clinical and environmental biology according to the standards ISO 15189 and 17025 in order to prototype a LIMS software at the National Institute of Hygiene of Morocco. This scheme incorporates a hundreds of procedures in different disciplines of clinical and environmental biology. Keywords: Model, Laboratory, Processes, Standard, LIMS. (12) The zoonoses data collection in Italy: an expert system for data quality management and improvement. S. Iannetti1, D.Cioci1, P.Colangeli1,M.G.Falcone2. 1 Instituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise “G. Caporale”, Campo Boario, Teramo, Italy, 2 Ministero della Salute, Ufficio III DGSAF, Corresponding author: [email protected] Introduction The European Union (EU) system for the monitoring and collection of information on zoonoses is based on Directive 2003/99/EC, which obliges the EU Member States to collect data on the occurrence of zoonoses, zoonotic agents, antimicrobial resistance, animal populations and food-borne outbreaks. Under Regulation 178/2002, EFSA is assigned the tasks of examining these data and publishing annual European Union Summary Reports (EUSR) in cooperation with the European Centre for Disease Prevention and Control (ECDC), which provides and analyses the data on zoonotic infections in humans. These reports illustrate the evolving situation in the EU and identify the pathogens that cause the most common zoonotic infections in humans. EFSA has developed a Zoonoses Data Model and a common dictionary (contained in pick lists) to be used by each reporting country, based on the Standard sample description, for all the items to be reported, with the aim of collecting data in a unique and uniform way and with the same semantic.In Italy, the zoonoses data collection takes place through the National information system for zoonoses data collection (SINZoo) (Colangeli et al., 2013) developed in compliance with the Directive 2003/99/EC by the Italian 21

reference centre for veterinary epidemiology and risk analysis (COVEPI) on request of the Ministry of Health (MoH), which is the national health authority responsible for the zoonoses data transmission to the EFSA. A common dictionary has been developed in SINZoo, integrated with the EFSA dictionaries and with other categorizations specifically developed at national level. During the first years of usage, data entry was free, without automatic controls, such as for choosing the sampling unit (animal, herd, holding, flock), thus increasing data granularity, but also for choosing the correct sampling stage and sample type according to the area of interest, thus increasing the possibility of inconsistent data. The data quality for a better analysis and understanding of the trend of zoonoses at national level has been increased, year after year, both by the EFSA and by the reporting countries. For this porpose, the EFSA launched in 2014 a granting programme, within the article 36 of EFSA’s Founding Regulation, to support the participating countries in updating and complementing their historical datasets in EFSA’s zoonoses databases. Materials and Methods Data entry into SINZoo is organised in four macro-areas: animal health, food, feed and food-borne outbreaks. It collects data aggregated per year, region/local health district, species/ matrix, kind of sampling context, kind of sampling place. Only data of antimicrobial resistance and food-borne outbreaks are sample based. The system foresees three different ways for data submission: manual data entry through web forms, standard files upload (XML files) and web-services (WS). Data entry is performed by specifically authorized regional operators and data entry/visualization may be customised according to the territorial competence: (Regions, Local health Authorities, veterinary public health institutes). Only the MoH can view data of all regions with any level of aggregation. Uploaded files are stored into temporary tables and processed off-line, according to specific validation rules and quality checks in accordance with national and EFSA’s business rules. The feeders are notified by email on the outcomes of the feeding process. Uploaded files and batch logs are kept into the system so that the full history of data entry can be traced. In this way, zoonoses data are subjected to several controls, which assure that they have been inserted correctly. More specifically, data are checked both during and at the end of the insertion: during data entry, the automatic logic system of truth tables checks that for each zoonoses the combination of the area of interest, each possible sampling context, stage and sampling unit has been entered correctly, thus avoiding inconsistent data. Each combination available in the truth table indicates the context, the stage, the sampling Unit allowed for the reported zoonosis in a specific area and for a category of species/matrix. The relationship among each variable is shown in figure 1. Moreover, for each item belonging to SINZoo there is a link (mapping) with the corresponding code of the Zoonoses Data Models and pick lists through a foreign key on table schema "EFSAMAPPING".

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Figure 1: Truth table structure and relationships At the end of the insertion period, after the final regional data validation, the Experts Panel performs the evaluation of zoonoses data collected, prior to their submission to the EFSA and entry their comments in specific Sinzoo section. This “expert system” was developed in 2014, funded by a EFSA granting programme with the aim of supporting the participating countries in updating and complementing their historical datasets (2008-2011 years) in EFSA’s zoonoses databases. The inconsistencies identified in the historical data are: I. Missing information to retrieve: II. Wrong information to correct: III. New information to provide: The first action put in place to evaluate the correctness of information reported into the historical prevalence dataset was to process the whole dataset by the truth table. In order to retrieve missing or incorrect data, it was considered worthwhile to analyse not all records, but only substantial combinations (SCs) of: matrix, sampling context, sampling strategy, sampler, sample type, sampling stage, sampling unit, sampling area. Each of these SCs was substituted with a new combination where missing or incorrect field/s were replaced according with a set of logical rules. Results The missing information was retrieved following a logical pattern based on the national legislation in place on the zoonoses covered by the project. The same logical pattern was used in SINZoo to build the truth tables specific for each zoonosis, in order to avoid mistakes during its feeding by the reporters. After the missing/unspecified information was retrieved, the rows containing wrong combinations of zoonosis/context/stage/unit were corrected and updated following both the logical pattern of the truth table and logical rules to ensure the coherence of the data retrieved. This control was made easier by the implementation of the web interface. A lot of missing information and inconsistencies was found in the animal prevalence historical data. The reason why a lot of information was missing is that most of the data to be retrieved was not mandatory in the past years. Table 1 shows the percentage of the information retrieved for animal prevalence historical data. Overall, the goal of the project was achieved for most of the information to be retrieved.

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REPORTIN SAMPLING G YEAR CONTEXT

SAMPLE SAMPLING R STRATEGY

SAMPLIN G STAGE

2008 2009 2010 2011

100% 100% 100% -

80% 86% 80% 87%

100% 99% 100% 87%

100% 100% 100% -

SAMP LE TYPE 100% 100% 100% 100%

SAMPLIN G UNIT 100% -

Total 89% 100% 100% 83% 100% 100% Table 1: Percentage of retrieved information for each SCs. Conclusions This project highlighted the importance of the quality of data during the collection and the feeding of any information system. The data to be amended in the EFSA’s zoonoses databases covered different aspects, from correcting double reporting, to updating and revising data on sampling stage, sampling context, sampler, sample type, sampling unit and sampling strategy whenever possible. The need to updated historical data led to improve the rules of the national data collection foreseen by the truth tables and to define new logics and algorithms that may be used for each data reporting. Moreover, the web interface implemented and integrated in SINZoo to retrieve historical data could be used for national data in routine way, to verify the presence of warnings/errors. References 1. “The Italian Information System on Zoonoses Data Collection” P. Colangeli, S. Iannetti, L. Ruocco, L. Forlizzi, D. Cioci and P. Calistri - Zoonoses and Public Health Article first published online : 4 JUN 2012, 1863-2378. Keywords: Data quality, Expert system, Information system, Zoonoses. (13) Application of a mobile platform for instant messaging, classification and transfer of medical data among doctors for faster medical diagnosis Kauthar Usop Mohammad 5 University, ENSET Rabat, Corresponding author: [email protected] With the emergence of mobile applications for instant messaging and data transfer, doctors have adopted these software technologies to better serve the patients especially in times of emergency. Colleagues have the possibility to send a photo of x ray, cross sections and wound or any other medical data via these platforms to seek advice, approval or precaution prior deciding on a set of medical diagnosis. This process has shown convenience for certain doctors in order to shorten the time needed for a medical procedure. The hindrance of such existing platforms are that (1) the personal and professional contacts are shuffled in one latform, thus, disordering the barrier between personal and professional cyber transaction. (2) The media files that are transmitted and received are not segregated according to its type and other signifying labels, thus, the media in the doctor’s phone are merged with other personal media files. (3) The doctors have no way to track back conversations into specific medical case due to the lack of classification of instant messaging in the existing platforms. This research study seeks to help connect doctors to their respective colleagues during medical diagnosis via a mobile application with a platform designed to accommodate the instant messaging according to the medical case, classification of media files according to facility, time of shift and medical case, and give the doctors the ability to segregating their personal instant messaging from the professional ones, for a timely and organized medical diagnosis and close-knit decision support system. Keywords: medical diagnosis, big data, medical data, artificial intelligence, expert system, mobile application, android development, mobile health 24

(14) Informatisation des centres de transfusion: expérience de Rabat Khadija .Hajjout, Amina Balk, Mohamed Benajiba Centre régional de transfusion sanguine de Rabat , Corresponding author: [email protected] La transfusion sanguine est une thérapeutique indispensable et irremplaçable de la médecine moderne. Elle consiste en une chaine de processus allant de la promotion du don de sang à la distribution des produits sanguins. La traçabilité des différentes activités garantit la sécurité transfusionnelle et par conséquent la sécurité des patients qui vont recevoir les produits sanguins. L’informatisation des différents processus contribue à assurer un haut niveau de sécurité. Le centre régional de Rabat a adopté depuis 1994, une application de gestion de sang Progesa de Mak System. Depuis Février 2016, le centre de Rabat a basculé vers une version WEB de l’application : eProgesa. Cette nouvelle version va permettre une meilleure gestion des processus et sera déployée progressivement au niveau de tous les centres du royaume. Ce déploiement va consolider la sécurité transfusionnelle non seulement au niveau régional mais également national en assurant d’une part la traçabilité de tous les dons effectués au niveau des différents centres et d’autre part une meilleure gouvernance pour le le Centre National de Transfusion Sanguine et d'Hématologie (CNTSH). Keywords: Sécurité transfusionnelle, Traçabilité, Informatisation (15) Promoting Population Health Through mHealth: Can Personal Health Management System Alter Personal Health Behavior?” Adam Bouras Department of Health Management and Informatics, School of Medicine, University of MissouriColumbia, CE747 Clinical Support & Education Building, DC006.00, Columbia, MO 65212, USA Corresponding author: [email protected] mHealth provides unprecedented medium to collect valuable information on patients’ episode of care. Several organizations and health studies are implementing and conducting mHealth interventions to improve and measure health outcome on their population. A meta-analysis study showed a conflicting results on effectiveness of these interventions. The study outlined a number of questions to further investigate the effect of mHealth. These questions pertain to assessing the effectiveness mHealth functionalities, the effectiveness of different car interventions in changing health behavior and whether these interventions are influenced by setting and/or by participants’ demographics. In this lecture, I propose outlines that are related to experimental design to investigate how mHealth can be used to help shape current health system and how it can be used to achieve an effective and efficient population health program. Keywords: mhealth, Population health, Experimental design. (16) Mobile Health Apps for people with mental and physical disabilities in Morocco 1,2

Hayat Sedrati, 4Chakib Nejjari, 2,3Hassan Ghazal National School of Public Health, Rabat, Morocco, 2TSE lab, National School of Computer Sciences and Systems Analysis, Mohammed V University in Rabat, Morocco, 3Polydisciplinary Faculty of Nador, University Mohamed Premier, Nador, Morocco, 4 School of Public Health, Morocco Corresponding author: [email protected] Modern aspects have emanated to fight disabling diseases using a promising progress in mobile communications and technologies for healthcare. The mobile health or “mHealth” technology can be an important tool to face scarcity of healthcare providers and problems in accessing to health services in Morocco. Nevertheless, commercial apps stores don’t have a quality label which can help health professionals and the general public to choose relevant and safe apps. The aim of this study is to classify retrieved apps from commercial stores, dedicated to mental and physical disabilities, to 1

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discern which was produced and what is to be improved. To take full advantage of mHealth possibilities, a rigorous evaluation on commercial apps stores is required and more development of physical health apps for patient’s rehabilitation use is needed. An ongoing comparison and assessment of these applications is being conducted in order to evaluate effectiveness and reliability of most pertinent application in a low and middle income country setting such as Morocco. Keywords: mental disability, physical disability, handicap, mHealth, Application, Morocco (17) Application of a Mobile Telemedicine Decision Support System for Psychiatric Data Acquisition of Mental Health Care Patients Nilo T. Bugtai, Kauthar S. Usop, Jericson Luke C. Ang Manufacturing Engineering and Management Department De La Salle University, 2401 Taft Avenue, Malate, Manila, Philippines Email: Corresponding author: [email protected] The conventional process of monitoring mental health patients is to asses them via face to face interaction within the healthcare facility. This happens as frequent as once a week to rarely to a once as a month session. Once diagnosed, there is tendency to becoming a no show patient, especially in heavy stigmatized societies. If the patient is not properly monitored and interacted with, the pharmaceutical and psychotherapy sessions will not be optimized. This research study seeks to provide handheld applications that regularly acquire eurocognitive, physical, cognitive data from the users for further evaluation or diagnosis by clinicians. The patient can have a private, simulated, artificial intelligent psychotherapist that allows the user to express his problems and frustration when monetary, physical or cognitive hindrances are present or when an actual psychologist is of hard access. Therefore, the user can have a cognitive behavioral treatment right from a mobile phone for immediate convenience. It is a fusion between psychology field and AI. The first prototype was done using expert system last 2015.The end result was to be able to help reduce mortality rate due to random crisis that occur far away from any emergency psychiatry available to psychosis patients., Keywords: artificial intelligence, expert system, decision support system, handheld devices, telemedicine, remote cognitive behavioral therapy, mobile health (18) La Maîtrise Statistique du Processus et analyse du Temps d’Attente des patients au Service d’Admissions et des Urgences Naima Ait Mouddene, Mouna Bouhaji, Manar Jallal, Samy Housbane, Zineb Serhier, Mohammed Bennani Othmani Laboratoire d’Informatique Médicale, Centre Hospitalier Université Ibn Rochd, Casablanca, Maroc Corresponding author: [email protected] Aujourd’hui l’amélioration de la qualité des soins et l'usage des méthodes réfléchies et rationnelles dans la gestion du fonctionnement des systèmes de santé est devenu un enjeu majeur des structures hospitalières pour garantir l’amélioration continue de la qualité des soins prodigués aux patients et rejoindre la route de la réussite. En étant l’une de ces structures, le service d’admissions et des urgences (SAU) n’échappe pas à ce contexte c’est pourquoi, les SAU sont obligés d’adopter de nouvelles méthodes à appliquer dans leurs processus de fonctionnements habituels. Depuis son introduction par Walter SHEWART en 1920, la Maîtrise Statistique du Processus (MSP) est une technique de pilotage qui a prouvé son efficacité pour évaluer la qualité d’un processus en poursuivant dans le temps la performance d’un ou de ces plusieurs indicateurs. En effet les délais d’attente des patients dans le SAU, constituent des indicateurs de l’assurance qualité de la prise en charge des citoyens à travers l’établissement de la carte de contrôle d’indicateur, son interprétation et son analyse prenant en compte les facteurs et les conditions de sa réalisation. L’objectif de cette mise au point est de décrire les principes d’une démarche qualité pour construire, comprendre la variabilité et suivre un indicateur de mesure de temps d’attente dans un SAU. L’évaluation quantitative des différents

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délais de passage au SAU permettrait d’identifier les causes qui sont responsables des durées excessives d’attente des patients chose qui nuit à la qualité de leur prise en charge. Keywords : Délai d’attente; Service des urgences; Assurance qualité; Roue de Deming; Processus (19) ECG signal de-noising using Wavelet Transform Nada.Beili, A.Hamyani, Mohammed.Belkasmi Laboratoire TSE, ENSIAS, University Mohammed V, Rabat, Maroc Corresponding author : [email protected] Abstract: ECG is a non-stationary signal. It is used for primary diagnosis of cardiac abnormalities such as arrhythmias, myocardial infarction and conduction defects. But real ECG signal is often contaminated by different noises, which makes a denoising step crucial in order to have a pertinent analysis. This article presents the ECG signal denoising using the wavelet transform. By revealing areas to improve in this method which has become widely used in signal processing. Résumé : ECG est un signal non stationnaire. Il est utilisé pour le diagnostic primaire d'anomalies cardiaques telles que l'arythmie, l'infarctus du myocarde et de troubles de la conduction. Mais ce signal souvent contaminée par des différents bruits, ce qui rend l’étape du débruitage primordiale pour faire une analyse pertinente. Cet article traite le débruitage du signal ECG en utilisant la transformée en ondelettes. En révélant les points à améliorer dans cette méthode qui est devenu largement utilisé dans le traitement du signal. Keywords: ECG, Wavelet transform, thresholding, denoising, non-stationary, orthogonal. (20) Telecardiology: Democratizing access to cardiac care Sahar Mouram*, L. Mouram**, S. Kaddar*** *Department of Cardiology-Electrophysiology - Marne la Vallée Hospital – Paris, France ** ESSEC Business School – Paris, France ***Department of Anesthesiology - Digestive Disease Group–Brussels, Belgium, Corresponding author: [email protected] Background - Developing countries face a plethora of issues in providing adequate cardiac care. Increased mortality rates, sudden deaths due to the lack of early care and prevention, increased healthcare spending and absenteeism are among the consequences of these issues. Telecardiology enables better access to the diagnosis and management of cardiac conditions. Thanks to decreasing costs and drastically improved technology, telecardiology can save lives, money and resources and revolutionize access to cardiac care in the developing world. Methods: - Telecardiology is a platform for the processing and remote interpretation of instantly transmitted electrocardiograms. The platform is secure and it respects patient data confidentiality. The electrocardiograms are processed and interpreted by experts which send by telephone their results within 5 minutes of receiving the ECGs. A full written report is emailed/faxed to the user afterwards. All reports are classified by patient and stored at the platform for future use. Results - Telecardiology has the potential to drastically improve access to reliable cardiac care in the developing world. Some of its most impactful benefits are: faster and more reliable cardiac diagnosis, remote follow-up of implants, democratizing access to cardiac care, saved time and money for patients, empowering general practitioners, enhancing healthcare, etc. - The biggest challenge facing the deployment of telecardiology in the developing world is the cost of the procedure and its coverage. However, economic growth and the development of health insurance create a favorable environment. Other challenges include lack of awareness among healthcare practitioners. Conclusion- Plummeting costs and increased technological performance are revolutionizing the medical sector, allowing for better, cheaper, and more reliable care. Telecardiology democratizes access to cardiac diagnosis and management in the developing world, which saves lives and promotes health and wellbeing of the populations. Keywords: Telecardiology; electrocardiogram; healthcare system 27

(21) Contribution of ultrasound robotic arm tele-operated during interventional procedure Ayoub Jean. Ultrasound department, CHU Trousseau, Tours, France, Corresponding author : [email protected] Background: Some interventional techniques require concomitant use of ultrasound guidance and fluoroscopy. To avoid X-Ray irradiation of the sonographer we suggested to use an ultrasound robotic arm for tele-operating echographic probe during the ultrasound guidance. Methods: A dedicated robotic arm holding a real ultrasound probe is remotely controlled from the expert site (Sonographer staying behind the X-Ray glass protection). The movements on the fictive probe by the expert are reproduced by the robotic arm on the real probe. Just before intervention, the probe and the robotic arm was located on top of the acoustic window of the Portal vein hepatic veins to be visualized during the intervention. This technique has already been validated for teleoperating echographic probe in a patient site from an expert site and allow isolated patient to have access to echographic diagnostic while staying in his living area. Results: this technique was tested with ISDN lines linking the expert site and the robotic arm by the side of the patient exposed to the X-Rays. during two TIPS (Transjugular Intrahepatic porto-systemic shunt) intervention. The expert by teleoperating the echo probe could follow the progression of the catheter from the Hepatic to the Portal vein system and help the surgeon to find his way to drive the needle inside the right portal vein. Conclusion: Robotized tele-echography provides similar information as direct examination and prevents exposure of the sonographer to X-Ray. Keywords: ultrasound robotic arm, teleechographic (22) Contribution of robotic arm tele-operated during interventional procedure of ablation Sahar Mouram*, S. Kaddar** * Department of Cardiology-Electrophysiology - Marne la Vallée Hospital – Paris, France ** Department of Anesthesiology – Digestive Disease Group – Brussels, Belgium Corresponding author: [email protected] Background: Robotic catheter ablation is performed at some centers. Robotic systems could improve navigation of the catheter, keep the catheter in a stable position, and shorten procedure times. In general, robotic catheter ablations have had similar outcomes as traditional (manual) catheter ablation, meaning that the success and complications rates aren’t significantly better or worse. Methods: A robotic ablation starts the same way as a traditional catheter ablation. The physician inserts a catheter into the groin and guides the catheter to the right side of the heart. After making a puncture in the septum, the wall that separates the right and left sides of the heart, the physician leaves the patient’s side and goes to the control system for the robotic system, which is usually located in an adjacent room. Results: Performing catheter ablation with a single point radiofrequency catheter can be technically challenging, particularly for physicians who have not performed many ablations. In theory, using a robot will simplify the procedure and decrease the expertise needed. The primary advantage is that robotic control provides very precise catheter navigation, right to the spot where the operator wants to go. Moreover, once the catheter gets there, it is extremely stable. Catheter instability is one of the reasons for long-term failure of AF ablation. Navigation is also easier with the robot, which will enable less-experienced operators to complete the procedure in a timely fashion. The use of robotic arm during ablation procedure has the benefit to isolate physicians from radiation exposure and eliminates the need to wear protective lead during the procedure. The robotic system can provide significant safety and comfort advantage for physicians. 28

Conclusion: This type of procedure, which is an important part of telemedicine, will positively impact public health and improve the management of atrial fibrillation, a disease that causes severe complications and negatively affects the prognosis of patients. Keywords: Telemedicine; Robotic Arm; AF ablation-healthcare system (23) Awareness of Nurses Towards Information Communication (TeleNursing) in Patient Care in Federal Teaching Hospital Ido-Ekiti, Ekiti State Nigeria. Paul I. Sunmbola1, A.A. Fakua2, P.O. Okimi3, P.M. Awotola4 1 School of Nursing, Federal Teaching Hospital, Ido Ekiti, Ekiti State. Nigeria, 2 School of Nursing, Federal Teaching Hospital, Ido Ekiti, Ekiti State. Nigeria, 3 Federal Teaching Hospital, Ido Ekiti, Ekiti State. Nigeria, 4 School of Nursing, Federal Teaching Hospital, Ido Ekiti, Ekiti State. Nigeria, Corresponding email: [email protected] Introduction: Any nurse who has spoken with a patient over the phone has practiced telenursing; it is not a new role, although advances in technology allow nurses to see, monitor, and/or interact remotely with patients/patient devices. Telenursing is defined as “the use of Telehealth/Telemedicine technology to deliver nursing care and conduct nursing practice.” Telenursing, Telehealth nursing, Nursing Telepractice is interchangeable. Nurses in all settings who employ telecommunications and health technologies, such as, audio, video, or data integrated into their existing practice are providing telehealth nursing. Combined with a body of knowledge and competencies used to deliver nursing care over distance telehealth nurses are successfully caring for patients remotely. Although telenursing is well established in developed nations, developing nations have much less activity. In Africa and particularly South Africa, some effective pilot telenursing schemes have been introduced. A further success has been in a wide variety of telehealth education programs which target nurses. However there is less awareness of telenursing in developing nations and in most health care institution which has reduced the quality and sustainability of the health system in these countries. Method: we conducted an analytical descriptive, non experimental research on all 100 subjects. Instrument for data collection was well-structured questionnaires which was distributed to respondents and analyzed using SPSS16. Results: 70 (70%) of the respondents were females, 30(30%) of the respondents were male. 86% of respondents were are of telenursing, while 66% of respondents does not utilize it in patient care.74% of respondents responded not to have undergone a telenursing seminar. On respondents’ perception on challenges facing use of telenursing equipment in patient care, 79% of respondents either agreed or strongly agreed that governments negative attitude was a challenge, 29% of respondents either disagreed or strongly disagreed that hospital policy was a challenge. Also, 44% of respondents agreed and another 44% strongly agreed that unstable electricity supply was a challenge, 68% of respondents either agreed or strongly agreed that lack of technology knowledge was a challenge. Conclusion: We conclude that the government and hospitals should formulate policies that will remove challenges to the use of telenursing in developing countries. Seminars, workshops, should be organized for nurses to improve the knowledge about the use and maintenance of such equipment. Telenursing should be included in curriculum of training for nurses. Keywords: Telenursing, Nigeria, developing countries, training (24) Setting up an information system for a newborn screening program Souad Chaqsare1, Sanaa Tok2, Mohammed Saouifi2, Fejjal Zakaria3, Diouane Fatima-Zohra3, Afaf Amarti4, Karim Ouldim4, Noureddine Boukhatem6, Swapna Abhyankar5, Hassan Ghazal6,7 1 Informatics Unit, National Institute of Hygiene, Rabat, Morocco, 2Department of Biochemistry/Hematology, National Institute of Hygiene, Rabat, Morocco, 3 High-tech Moroccan School of Computer Engineering, Rabat, Morocco, 4 University Hospital Center Hassan II, 30000 Fez, Morocco, 5 Regenstrief Institute, Inc. Indianapolis, IN, USA, 6 Laboratory of Genetics, 29

Physiology & Ethnopharmacology, Faculty of Sciences Oujda, 7 Polydisciplinary Faculty of Nador, University Mohammed Premier, Nador, Corresponding author: [email protected] eHealth is the use of information and communication technologies (ICT) for health. In its broadest sense, eHealth is about improving the flow of information, through electronic means, to support the delivery of health services and the management of health systems. The successful implementation of eHealth requires strategies that are aligned with the national health priorities. In low and middle income countries (LMICs), maternal, newborn and child health programs have incorporated eHealth strategies to offer services such as pregnancy and birth registries, immunization and nutrition tracking. One of the fields where the necessity and the opportunity of setting up a national eHealth strategy are newborn screening (NBS) programs. NBS for severe metabolic and hematologic disorders, that can cause death or may hinder an infant’s normal physical or mental development, are well established in high-income countries. These disorders can be addressed by effective therapies at the early stages. In LMICs, however, newborn health care is primarily focused on preventing malnutrition and infectious diseases, because these remain the main causes of child mortality in these countries, and detection of genetic diseases is usually not a priority in their public health agendas. Establishing a sustainable NBS program requires building an information system or eHealth infrastructure that allows rapid and effective bi-directional communication between the NBS actors. These systems track clients (babies) from their first contact with the Screening Center through their last follow-up test, producing worksheets, result reports, letters, and summaries for archival storage. Using internationally-accepted health information exchange standards allows data exchange and collaboration with international NBS partners. Recently, a pilot NBS program is being established in Morocco. Screening is done in the first few days of life, and the goal is early identification of healthyappearing newborns before they suffer significant morbidity or mortality. NBS programs are a collaborative effort between public health departments, hospitals, laboratories, and pediatric care providers. Establishing a sustainable NBS program requires building an information system that allows rapid and effective communication between the NBS actors. We are developing a NBS Information System (NBSIS) that will be capable of handling the information processing needs of the prospective Moroccan NBS program. We first analyzed the information workflow of the proposed national NBS program in order to determine its information processing needs, which include: 1) collection of newborn and maternal data; 2) reporting NBS results for both in-range and out-of-range screens (i.e., cases) in real time; 3) exchanging information between various independent, heterogeneous systems; and 4) enabling population-based surveillance. Second, we evaluated the capabilities and limitations of existing information systems. Third, we designed a web application that can be used to collect newborn and maternal clinical data, store laboratory screening results, collect data over time for cases identified by NBS, and allow secure data access to all of the relevant NBS actors. We are evaluating the HL7 health information exchange standard as well as the NBS coding and terminology developed by the US National Library of Medicine for potential adoption and implementation. The NBSIS will be used to track babies from their first contact with the Screening Centers through their last follow-up test and will be capable of producing worksheets and creating result reports for archival storage. Using internationally-accepted health information exchange standards will also allow data exchange and collaboration with international NBS partners. Keywords: Newborn screening, Health Information System, Morocco, national program (25) Medical Genomics Big Data Challenges Yassine Souilmi1,2,3, Jae-Yoon Jung2,5, Alex Lancaste2, Ettore Rizzo4, Saaid Amzazi1, Hassan Ghazal3, Dennis Wall5, Peter Tonellato2 1 Department of Biology, Mohammed V University in Rabat, Rabat, Morocco 2 Departement of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA 3 Department of Biology, Mohamed First University, Oujda/Nador, Morocco 4 Department of Electrical, Computer and Biomedical Engineering, University of Pavia 30

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Department of Pediatrics, Division of Systems Medicine, Stanford University, Stanford, CA 94305, USA, Corresponding author: [email protected] The dramatic fall of next generation sequencing (NGS) cost in recent years positions the price in range of typical medical testing, and thus whole genome analysis (WGA) may be a viable clinical diagnostic tool. Modern sequencing platforms routinely generate petabyte data. The current challenge lies in calling and analyzing this large-scale data, which has become the new time and cost ratelimiting step. To address the computational limitations and optimize the cost, we have developed COSMOS, a scalable, parallelizable workflow management system running on clouds (e.g., Amazon Web Services or Google Clouds). Using COSMOS, we have constructed a NGS analysis pipeline implementing the Genome Analysis Toolkit - GATK v3.1 - best practice protocol, a widely accepted industry standard developed by the Broad Institute. COSMOS performs a thorough sequence analysis, including quality control, alignment, variant calling and an unprecedented level of annotation using a custom extension of ANNOVAR. COSMOS takes advantage of parallelization and the resources of a high-performance compute cluster, either local or in the cloud, to process datasets of up to the petabyte scale, which is becoming standard in NGS. This approach enables the timely and costeffective implementation of NGS analysis, allowing for it to be used in a clinical setting and translational medicine. With COSMOS we reduced the whole genome data analysis cost under the $100 barrier, placing it within a reimbursable cost point and in clinical time, providing a significant change to the landscape of genomic analysis and cement the utility of cloud environment as a resource for Petabyte-scale genomic research. Keywords: Big data, medical genomics, cloud computing, NGS (26) Metagenomics analysis of The Moroccan Human Gut Microbiome Imane Allali 1,2,5, Noureddine Boukhatem 2, Leila Bouguenouch 4, Hanaa Hardi 2, Maria Belen Cadenas5, Karim Ouldim4, Andrea Azcarate-Peril5, Saaïd Amzazi1, and Hassan Ghaza l2 3 1 Laboratory of Biochemistry & Immunology, Faculty of Sciences, University Mohammed V, Rabat, Morocco,2Laboratory of Physiology, Genetics & Ethnopharmacology, Faculty of Sciences of Oujda, University Mohamed Premier, Oujda, Morocco, 3Polydisciplinary Faculty of Nador, University Mohamed Premier, Nador, Morocco, 4Department of Molecular Genetics, University hospital Hassan II of Fez, Fez, Morocco, 5Department of Cell Biology & Physiology, and Microbiome Core Facility, School of Medicine, University of North Carolina, Chapel Hill, NC, U.S.A., Corresponding author: [email protected] Understanding the relationship between the human gut microbiome and health is one of the biggest challenges. The study of the human microbiome has the potential to impact many areas of our health as 90% of our cells are bacteria, and the microbial genome contains 200 times more genes than the human genome. The advances in new sequencing techniques (NGS) have revolutionized microbiology research allowing a great advancement on our understanding of the link between microbiome composition and the host organism. Nowadays, it was recognized that gut microbiome has an important physiological role to the point to be considered as a ‘neglected organ’ that is essential to preserve and understand. In addition, many studies have established a link between the gut microbiome composition and several diseases such as colorectal cancer, obesity, diabetes, allergies, inflammatory bowel disease and crohn’s disease. However, the impact of the microbiome in the etiology of these diseases remains not yet elucidated because of the complexity of the gut microbiome composition. The human gut microbiome is a complex community of 1013 to 1014 microorganisms and it is specific to each population. The aim of this study was to characterize the gut microbiota of the Moroccan population. Dozen Stool samples of Moroccan healthy subjects were characterized by 16S rRNA amplicon sequencing. Obtained reads were analyzed using our bioinformatics pipeline that includes: Trim and filter reads, Operational taxonomic Units (OUT) picking, classification and phylogenetic tree construction, microbial diversity analysis, and functional annotation. Our findings indicate that healthy samples were enriched in Bacteroidetes (N=62.8%) while they were depleted in 31

Firmicutes (N=28.4%). Despite the small number of patients included in the study, we observed overrepresentation in Prevotella genus (N=26.0%) and Bacteroides genus (N=17.8%). This is the first study conducted in the Moroccan population that aimed to characterize the gut microbiome composition. Data from this small cohort warrant a larger study that will include subjects from different Moroccan locations. Understanding the intestinal microbiota composition will open new perspectives for struggle against diseases, prevention rather than cure and will lead to the development of novel strategies for the diagnosis and treatment of diseases. Keywords: metagenomics, next-generation sequencing, computational tools, bioinformatics, data analysis, microbiome, gut, colon (27) Revealing the Microbial diversity extent of the Moroccan Marine ecosystems using Bioinformatics tools 1,2

Bouchra Chaouni, 3Noureddine Boukhatem, 3Soumia Essayeh, 1,3Rajae Chahboun, 3Abderrahim Bouali, 4Said Barijal, 5Mohamed Timinouni, 6Fatima El Otmani, 5Mohammed Bennani, 2El Houssine Zaid, 1,3Hassan Ghazal 1 Laboratory of Physiology, Genetics & Ethnopharmacology, Faculty of Sciences of Oujda, Morocco 2 Laboratory of Physiology, Faculty of Sciences, Mohammed V University in Rabat 3Polydisciplinary Faculty of Nador, University Mohammed Premier, Nador 4Faculty of Sciences & Technologies, Abdelmalek Essaâdi University, Tangier 5Laboratory of Microbiology, Institut Pasteur du Maroc. Casablanca, Morocco, 6Microbiology, Health & Environment Team, Faculty of Sciences, University Chouaib Doukali, El Jadida. Corresponding author: [email protected] A metagenomics approach is used to explore the microbial diversity of Moroccan marine ecosystems. Surface water samples were collected from different marine Moroccan sites including Mediterranean and Atlantic. DNA extracted from filtered samples have been sequenced. In order to determine the community structure; bioinformatics analysis was conducted using various tools. All reads were processed by the NGS analysis pipeline of the SILVA rRNA gene database project (Quast et al., 2013). Each read was aligned using the SILVA Incremental Aligner (Pruesse et al., 2012) against the SILVA SSU rRNA SEED and quality controlled (Quast et al., 2013). After these initial steps of quality control, the unique reads were clustered in operational taxonomic unit (OTUs), on a per sample basis, and the reference read of each OTU was classified. The classification was performed by a local nucleotide BLAST search against the non-redundant version of the SILVA SSU Ref dataset (www.arb-silva.de) using blastn (Camacho et al., 2009). The classification of each OTU reference read was mapped onto all reads that were assigned to the respective OTU. This yields quantitative information (number of individual reads per taxonomic path). In order to perform Taxonomic analysis, we used QIIME, which is an open-source bioinformatics pipeline for performing taxonomic analysis from raw DNA sequencing data. 16s rRNA are annotated using the Greengenes reference database. As for the functional analysis, InterProScan, which is a sequence analysis application that combines different protein signature recognition methods into one resource, is used. Matches are generated against predicted CDS, using a sub set of databases. A summary of Gene Ontology (GO) terms derived from InterPro matches to our sample is provided for functional annotation. The outcome of this pipeline shows that our sites were enriched in a large number of known bacteria representing 27 phyla, 56 classes, 98 orders, 162 families, 229 genus and 80 species plus a high percentage of unclassified microbes. The most abundant phyla are Proteobacteria, Cyanobacteria, while others form a low percentage and some of them are specific to each site. The functional analysis also showed similarities between all the marine sites in terms of their associated biological processes, cellular components and molecular functions. Further investigation of unclassified bacteria will be conducted and the functional annotation of the new genomes for gene discovery and new metabolic pathways prediction will be followed.

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References: Camacho C. Coulouris G. Avagyan V. Ma N. Papadopoulos J. Bealer K. and Madden T. (2009). BLAST+: architecture and applications. BMC Bioinformatics, 10(1):421, 2009. Pruesse E. Peplies J. And Gl ö ckner FO. (2012). SINA: accurate high throughput multiple sequence alignment of ribosomal rna genes. Bioinformatics. Quast C. Pruesse E. Yilmaz P. Gerken J. Schweer T. Yarza P. Peplies J. Gl ̈ockner FO. (2013). The SILVA riboso- mal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Research, 41(D1):D590–D596. Keywords: Microbiome, Marine, metagenomics, Bioinformatics, Morocco, lagoon (28) Laboratory Information Management System adapted to support genomic and metagenomic analysis for diagnosis Patrizia Colangeli, Adriano Di Pasquale, Monica Ferrilli, Silvio Sacchini, Daniele Zippo, Samuel Perticara, Maurilia Marcacci, Marco Di Domenico, Iolanda Mangone,Claudio Patavino, Massimo Ancora, Massimiliano Orsini and Cesare Cammà Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise “G. Caporale” (IZSAM), Campo Boario, Teramo, Italy, Corresponding author: [email protected] Introduction Ten years ago was born a new technology called Next Generation Sequencing (NGS), and, within a short time it has undergone a rapid evolution in terms of increase in the production of data capacity and lower costs. The NGS applications are various: starting from sequencing of new genomes, analysis of the transcriptome until the microbiome study through a metagenomics approach (1). In a microbiology lab, the traditional diagnostic path is based on the isolation of bacteria and virus using specific media or cell cultures so as it can be able to identify and characterize the pathogen; that’s a long and sometimes difficult process especially when there is an unknown variant about which there are no specific laboratory tests. The metagenomics approach provides a quick turnaround time as it not requires culture isolation and subsequent pathogen typing. Anyway the metagenomics is still a technique for research, not yet for routine laboratory activities. In IZSAM the current Laboratory Information Management System (LIMS) was adapted to also trace and support the genomic analysis. Materials and Methods Protocols and workflows streamline and a sudden interpretation of produced data (2) (Figure 1), are making accessible the genomic sequencing of microorganisms and subsequent bioinformatics analysis on the data for routine diagnosis at IZSAM. The internal LIMS (called SILAB) has been adjusted to trace all WET and DRY analysis on the original sample, to simplify and support several steps needed and to make activity more efficient, controlled and recorded. Indeed we have traces of all sample origin metadata (sampling place, sampling date, matrix, species, purpose), all tests results and we are able to simplify lab’s job. Results In most cases, the first step is in charge to the Analyst of “traditional” Diagnostic Sections who asks for genomic analysis of bacterial or viral strains derived from old samples already identified by a Unique Submission Number (NRG). Basically it is "another distribution" but it produces in SILAB a new simplified Acceptance record with a new NRG. It reads from a CSV file, with the samples codes that you want to sequence. Through the ID of the strain/RNA/DNA (which recalls the original NRG plus the univocal sample progressive), SILAB provides all metadata (sampling point, reason, material, species, customer, owner etc.) and can show all tests results of the original sample. Using SILAB, you can distribute for each sample, NGS test and / or metagenomic test (De Novo, FlaA,MLST,...) Bioinformatic staff reads the working sheet from SILAB and pull out it as a CSV file, select sequencing samples, complete sample sheet and use it to start test. When the sequencing and the quality test process are completed, the bio-informatics receive an email with a result file that is read 33

by SILAB for uploading results. The result of NGS test is the location (URL) of the output file: FASTQ trimmed. As in "tradizional" tests, SILAB requires an additional technical evaluation to categorize the sample as compliant or not. In this case the values are adapted to indicate the distance from any reference Cluster (near = Positive away = Negative). This field permits a fast extraction of all samples with genome sequence near to a reference Cluster (derived by human patients strains). To collect all data (row data, fastq and metagenomics files) a data center was organized with servers in cluster and two different environments one dedicated to NGS analysis and the other dedicated to metagenomics tests (Figure 2). Conclusions Genotyping of pathogens is an essential step in the surveillance of infectious diseases and for studying of epidemic outbreaks. SILAB usage, according with sequencing technologies, put in order operational flow, reduced faults, made available data to all authorized users. Above all, it is a support for the analysis and finally for diagnosis as thanks to a button, can get the history of a sample from which the strain comes from. References 1) DEL CHIERICO, F., ANCORA, M. MARCACCI, M., CAMMÀ, C., PUTIGNANI, L., CONTI, S. (2015) Choice of Next Generation Sequencing pipelines in:"Bacterial Pangenomics" Methods in Molecular Biology, Vol. 1231 11/2014, ISBN: 978-1-4939-17198, DOI: 10.1016/j.ttbdis.2016.03.012 2)MARCACCI M, ANCORA M, MANGONE I, TEODORI L, DI SABATINO D, DE MASSIS F, CAMMÀ C, SAVINI G, LORUSSO. (2014) Whole genome sequence analysis of the arctic-lineage strain responsible for distemper in Italian wolves through a fast and robust next generation sequencing protocol. J Virol Methods. 202:64–68, DOI: 10.1016/j.jviromet.2014.02.027 Keywords: Molecular typing, Next Generation Sequencing, Laboratory Information Management System

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SPECIAL SESSION: TELEMEDICINE IN MEDITERRANEAN COUNTRIES ------------------------------------------------------------------------------------------------------------------------------------------

The eMedMed Project Arch. Pierpaolo Saporito OBSERVATORY FOR CULTURAL AND AUDIOVISUAL COMMUNICATIONCREATED BY UNESCO IN 1997, ACTING AGENCY OF THE UN INFOPOVERTY WORLD CONFERENCE

Southern Mediterranean Healthcare System Development through the use of ICTs The eMedMed Project, created under the auspices of the Union for the Mediterranean and validated by the UN ECOSOC, has to task of improving through the new technologies of Telemedicine the health conditions of the Southern Mediterranean Countries. The eMedMed project aims at providing e-services through an innovative platform system that links main, local and peripheral hubs, overcoming a large amount of healthcare problems, such as malnutrition, obesity, and the chronic diseases brought on by sedentary lifestyles and tobacco smoking. Moreover, the project is specifically devoted to face the health security challenges that the migrant emergency is provoking. Taken cognizance that the potential of digital services in the field of education and healthcare is still largely unexploited and that it would be a fundamental catalyst in the economic and social development of the Southern Mediterranean shore, the eMedMed project will use Information and Communication Technologies (ICTs) to solve healthcare gaps afflicting these countries. The area of intervention of the eMedMed project is the Southern Mediterranean shore. In particular, it will be implemented in Egypt, Libya, Morocco and Tunisia. The partner hospitals that will act as “Local Hubs” for the Project are: • Morocco: Rabat, Moroccan Society for Telemedicine and e-Health; Faculty of Medicine of Fews, University of Sidi Mohammed Ben Abdellah, Fes • Egypt: Cairo, Nile Badrawi Foundation for Education and Development. • Libya: Tripoli, Diabetes Hospital; National Center For Disease Control • Tunisia: Tunis, Association for Promoting Pulmonology and Allergology • Italy: during the XXI Euromediterranean Conference held in Catania in February 2016 an agreement was signed by the Mayor of Catania Enzo Bianco and the President of OCCAM Pierpaolo Saporito, in order to create in Catania the “Hub Centre of Catania for Health security, migrants emergency and supportive development in the Mediterranean area” to monitor the health security in the Mediterranean Area. The main tasks are: • boosting the capacity of national health-care systems to make health services accessible to the population at large with the use of telemedicine; • increasing medical and paramedical professionalism and performance through continuous etraining; • giving remote assistance in the delivery of health-care; • integrating knowledge in the region via the e-Services Mediterranean Platform, linking service users and service providers, as the Italian hospitals and centers of excellence; • giving assistance during the migrants landing on the Mediterranean shores.

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The eMedMed Project will address four tiers of beneficiaries: • The first is the tier of medical institutions involved at the country level that will benefit from professional advancement of staff, upgrading of existing technology, and enhancement of services quality and accessibility; • The second is the tier of assisted population, with an emphasis on patients located in remote communities or communities with scarce presence of healthcare structures and services; • The third is the tier of national health systems where the capacity installed is meant to be replicated at a larger scale; • The fourth is the regional tier where a platform for sector integration will be launched. The program has been developed by OCCAM1 in partnership with IITM, the International Institute of Tele-Medicine, an independent scientific and technological structure involved in research, development and transfer of ICT projects and initiatives in medicine and healthcare. In the ambit of the eMedMed Project, during the XXI Euromediterranean Conference is was also decided to launch a Mediterranean Master of Telemedicine, together with the universities of the Mediterranean Basin, in order to train homogeneously the medical and paramedic staff, whose preliminary study will be assigned to the professors Hassan Ghazal (University Mohammed Premier), Francesco Basile (University of Catania), and Francesco Sicurello (University of Milano Bicocca). 1 The Observatory for Cultural and Audiovisual Communication (OCCAM) was created by UNESCO in 1996. Since 2003 OCCAM has been formally associated to the UN Department of Public Information and since 2005 it enjoys Special Consultative Status with the ECOSOC. Since 2001 OCCAM has organized the Infopoverty World Conference, held on a yearly basis at the UN Headquarters in New York. More than 1000 institutions and leaders have participated in the event, making a very fruitful exchange of best practices and converging activities possible

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Moroccan eGov strategy for Health Mrs. Samia Chakri Director, Department eGov, Ministry of Industry, Trade, Investment and Digital Economy La présentation se focalisera sur les points suivants : 1) L’eGouvernement au Maroc, 2) l’évolution des TIC au Maroc / historique de l’évolution de 1995 – 2009; 3) La stratégie Maroc numérique 2013 ; 4) la Gouvernance des services publics orientés usagers ; et 5) la confiance numérique. La Synthèse des réalisations e-Gov : -Bilan des réalisations e-Gov; -Extrait de quelques projets e-Gov; -Zoom sur quelques réalisations. -Les services mutualisables et métiers, -Indicateurs de l’e-Gouvernement et -Facteurs clés pour réussir un programme eGov.

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Telehealth and telemedicine in the Middle East and North Africa Dr. Najeeb Al-Shorbaji Vice-President for Knowledge, Research and Ethics e-Marefa (www.e-marefa.net), Amman, Jordan Former Director of Department of Knowledge Management and Sharing, World Health Organization The third global survey on eHealth conducted by the WHO Global Observatory for eHealth (GOe) has a special focus – the use of eHealth in support of universal health coverage. It was completed in August 2015. 125 countries completed the survey representing a 64% response rat.. The scope of the survey was broad;

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survey questions covered diverse areas of eHealth, from electronic information systems to social media, to policy issues and legal frameworks. Indicators covering the following aspects were included: 1. 2. 3. 4. 5. 6. 7. 8.

eHealth foundations Legal frameworks for eHealth Telehealth Electronic health records Use of eLearning in health sciences mHealth Social media Big data

As the focus of this conference is telehealth and telemedicine in the MENA Region (Middle East and North Arica), this summary presents high level summary of the results from the WHO Eastern Mediterranean Region (EMR) in response to the Telehealth questions in the survey 14 EMR countries out of 22 completed the survey representing 63.6%. They are Afghanistan, Bahrain, Iran, Iraq, Jordan, Lebanon, Morocco, Oman, Pakistan, Qatar, Somalia, Sudan, Syria and Tunisia. \We added to this overview Algeria and Mauritania as they are both in North Africa. The majority of countries (10 out of 14) have tele-radiology programmes ether established at the national level, pilots or informal. Two countries have an established national tele-dermatology programme, while three countries have either pilot or informal programmes. Tow countries have tele-pathology national programmes, while three countries have pilot or informal programmes. One country has an established national tele-psychiatry programme and one country has an informal programme. Two countries have an established national remote patient monitoring programme and two countries have pilot programmes for the same. The above data shows the very week telehealth and telemedicine programmes in the MENA region. This might be interpreted as a result of weak information and communication technology in health care institutions including hospitals and lack of funding. The absence of culture of offering and receiving health and medical services at distance. It is most worrying to note that countries like Egypt, Kuwait, Palestine, Saudi Arabia, United Arab Emirates and Yemen did not complete the survey. The author of this review knows for fact that there are national telemedicine programmes in these countries. Two other countries did not report (Djibouti and Libya). I would like to focus on Jordan as I am aware of some of the activities in the country. Jordan has been pioneering in using information and communication technology for health as the first telemedicine project in the Region was initiated at the King Hussein Medical City in 1976. There has been a number of commercial telemedicine services provided by private clinics for remote consultation and second opinion. King Hussein Cancer Centre provides telemedicine services through its collaboration with specialised cancer centres in the US. Two recent projects have been launched including: 1. The Jordanian and Palestinian Telemedicine Network, launched by the Palestinian ministry of health in cooperation with the German Development Cooperation (GIZ) on behalf of the Federal Ministry for Economic Cooperation and Development. It was established in 2009, with the aim of enhancing medical consultation among doctors in Palestine and Jordan. Around 150 doctors have benefited from GIZ’s training in Jordan and Palestine, according to Yousef, who said five hospitals in the Kingdom have benefited from the project.

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2. Jordan Telehealth Network. The project has been supported by Cisco company aiming to connect three hospitals and providing video technology with high-definition video and advanced audio. Two tele-clinics have been successfully implemented and are fully operational in two remote hospitals in north and south of Jordan. The first clinic was launched in 2011 at Mafraq Governmental Hospital (MGH) in the north of Jordan and the second was launched in 2012 at Queen Rania Hospital (QRH) in the south of Jordan. The two clinics connect patients from the north and south of Jordan with specialists at a major hospital (PHH) in Amman.

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Telemedicine in Morocco Ghazal Hassan Moroccan Society for Telemedicine and eHealth / University Mohammed Premier, Oujda/Nador, Morocco Telemedicine refers to health and medical services performed using Information and Communication Technologies. Telemedicine in Morocco presents opportunities for the national health systems but faces number of technical, legal, societal and cultural obstacles. If telemedicine is not well developed, the awareness of health professionals and policy makers is growing. Number of telemedicine initiatives have been launched. They concern various fields such as elearning, teleoncology, teleradiology, telecardiology, and teleechography. The latest was one of the most concluding telemedicine experience and consists of Mobile health ultrasound patrol pilot project for diagnosis of pregnancies with risks in the region of Fes funded by Qualcomm Wireless Reach™. The goal of this mHealth project was to validate how advanced wireless technologies and connected portable ultrasound devices can provide access to state-of-the-art imaging diagnostics in places it has never been available before. This Mobile Ultrasound Patrol project enabled physicians located in different cities to quickly review the same data and collaborate on patient care. The use of wireless technologies slashed time delivery of medical data for review, cut diagnostic review or second opinion time and reduced costs per patient. Other recent telemedicine initiative concerns mobile health Tubercolosis in the city of Sala by the Korean Cooperation. Earlier, in 2007, a teleoncology pilot Project between the Oncology Institutes of Rabat and Brussels have been conducted. In addition, Health Information Management System are being implemented in a growing number of hospitals throughout the country. However, Electronic Medical Records are not yet an essential cornerstone for supporting health care services. In 2007, an international teleeducation network for pediatrics has been established between the child hospitals of Washington, Rabat and Marrakech to improve community and healthcare provider knowledge and practice related to children’s healthcare issues. US Physicians could provide clinical information, share medical advancements and conduct training sessions with healthcare professionals in both Moroccan cities. This project resulted in the installation of a telemedicine station in Rabat and training of 40 physicians and staff. The Telecardiology project component with Marrakech University hospital helped to identify barriers for sustainable implementation that include reliable technology, consistent bandwidth, satellite time, time zone, and language. Number of international telemedicine events have been organized in the country. The Moroccan society for Telemedicine and eHealth (MsfTeH) has been founded after the 2010 Casablanca international conference on eHealth thanks to the support from the International Society for Telemedicine and eHealth and WHO directorate of knowledge management and sharing. The MSfTeH is promoting eHealth and telemedicine in the country and organized the 9th Euro Mediterranean conference for Telemedicine and Medical Informatics in 2013 in partnership with the Euro Mediterranean Association for Telemedicine and Medical Informatics. This resulted in the preparation of the eMedMed proposal for training in telemedicine for North African countries in partnership with the Italian based NGO, The Observatory for Cultural and Audio-visual Communication (OCCAM) and the International Institute for Telemedicine. The MSfTeH have also been participating in the annual international visioconference by the French Telemedicine Network, Catel, since 2014. Earlier, representative from Morocco participated in the foundation of The Arab Telemedicine Society under the 38

umbrella of the Arab Medical Union in October 1999. Recently, Morocco hosted the first exploratory seminar where initial conclusions confirmed that there is significant interest in, and potential for, cooperation in the area of eHealth policy and its implementation between EU and Southern Mediterranean countries. However, number of challenges remain to be overcome including the lack of a national ehealth strategy and legal framework, lack of awareness of potential e-health benefits; privacy concerns; weakness of information infrastructure in the hospitals; and lack of skilled personnel. The mission of IT departments in the ministry of health also needs to be well defined. In term of infrastructure, Morocco retains one of the most advanced telecommunications infrastructure in Africa, with three fixed and mobile network operators. Morocco also has one of the highest mobile penetration rates in the region. This demonstrate the opportunities for telemedicine development in the country. -------------------------------------------------------------------------------------------------------------------------------

Etat des lieux de la Cybersanté au Mali Dr Ousmane Ly, Directeur Générale de l’Agence Nationale de Télésanté et d’Informatique Médicale (ANTIM). Le processus d’informatisation du système de santé au Mali est en cours depuis 1989 : - DESAM (Développement Santé du Mali) a été conçu pour la gestion des données de l’information sanitaire des premiers et deuxième niveaux de la pyramide sanitaire, qui évolue aujourd’hui vers le DHIS2 (District Health Information Software 2), - Développement d’un logiciel pour les hôpitaux (PharmaHos) qui est en réseaux pour la gestion des stocks de la pharmacie et le bureau des entrées pour sécuriser les recettes dans les hôpitaux), qui devrait évoluer vers un dossier médical informatisé - Système Numérique d’Information Sanitaire Intégré (SNISI) pour la collecte et la transmission des données à travers la téléphonie mobile qui a une bonne couverture géographique et un bon taux de pénétration. Sur ce système 791 agents de santé (DTC, Chargé SIS) recueillent et transmettent les données avec les téléphones portables de la flotte mobile en place par rapport au paludisme, la nutrition, la santé de la reproduction, la cécité et la vaccination (Chaque programme exploite ces données sur les serveurs). - La carte sanitaire numérique qui est la localisation par GPS de plus 1400 établissements de santé à travers le pays. Actuellement c’est la phase de numérisation des dossiers patients qui est en cours avec: - Le progiciel de dossier de santé électronique centré sur le patient, OpenClinic qui gère différents aspects des structures de santé (Bureau des Entrées, Dossier médical du patient, Laboratoire, pharmacie…). o Opérationnel dans 2Hôpitaux sur 12, 5 Centres de santé de santé de référence (CSRef) sur 65 et 2 établissements de santé de premier niveau (Privés). - DataSanteMali, qui est un outil pour les unités de soins primaires avec mise en place d’un dossier médical partagé. o Il a été déployé dans 2 CSCom sur 1234 CSCom opérationnels. o L’expérience pilote du Mali vous sera présentée dans l’intervention de Monsieur Pierre Coste qui va suivre Avantages de la numérisation: o la réduction des erreurs médicales, o l’amélioration de la qualité de prise en charge du patient ; o l’amélioration de l’archivage des dossiers patients ; o l’accroissement de la productivité des structures, o La sécurisation des dossiers patients par la diminution des risques de perte liés aux conditions d’archivage (incendies, accès physiques par tierce personne) 39

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la disponibilité de la bonne information aux autorités sanitaires en temps réels pour la prise de décision.

Les difficultés: o L’insuffisance des moyens financiers (pour les investissements initiaux), o La problématique de la gestion du changement o Particulièrement les questions d’interopérabilités entre les différentes solutions technologiques. En terme de télémédecine proprement parlé, plusieurs projet pilote ont été initié et sont arrivé à terme après la fin du financement des partenaires. L’agence de télésanté et d’informatique travaille actuellement à rendre durable les activités de télémédecine. C’est dans ce cadre qu’elle collabore avec le Centre Hospitalier-Universitaire de Caen, sur un programme de télémédecine Humanitaire. Les téléconsultations ont concerné les patients ayant des malformations oro-maxillo-faciales dont la prise en charge est difficile, voire impossible au Mali.

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Committees Conference Committee Chairs Pr. Hassan Ghazal (MsfTeH & University Mohammed Premier, Morocco) Pr. Francesco Sicurello (IITM & University of Milan Bicocca, Italy) Dr. Khattabi Asmae (National School of Public Health, Morocco) Mrs. Samia Chakri (Ministry of Industry and Digital Economy) Honorary Chairs BELALIA Abdelmounim, Director of the National School of Public Health ABAACROUCHE Mina, Former Director of the National School of Public Health AZDI MOUSSA Ali, Dean, Polydisciplinary Faculty of Nador IBRAHIMI Adil, Dean, School of Medicine, Fes NEJJARI Chakib, Dean, School of Public Health, UMVI, Casablanca LAHLOU Anas, President, American University of Leadership Morocco Foundation, AULMF, Rabat SENOUSSI Mohammed, Vice President, AULMF, Rabat SICURELLO Francesco, President, IITM, Milano SAPORITO Pierpaolo, President, OCCAM, Milano GERENDASY Dan, Officer, International Cooperation, NLM, NIH

Scientific Committee Hassan Ghazal (Morocco)

Francesco Sicurello (Italy)

Peter Tonellato (US)

Samia Chakri (Morocco)

Asmae Khattabi (Morocco)

Tatiana Tatusova (US)

Najeeb Al-Shorbaji (Jordan)

Bella Sergio (Italy)

Vassiliki Koufi (Greece)

Abdelbadeeh Salem (Egypt)

Pierpaolo Saporito (Italy NU)

Chakib Nejjari (Morocco)

Habib Ghedira (Tunisia)

Marcello Bracale (Italy)

Karim Ouldim (Morocco)

Christian Axiak (Malta))

Mohamed Abd-allah (Egypt)

Johnny Heubri (Lebanon)

El azami E. Mohammed (Morocco)

Cherradi Hanae (Morocco)

Josè Luis Monteagudo Pena (Spain)

Luca Buccoliero (Italy)

Giancarlo Mauri (Italy)

Soad Bosseri (Libya)

Anamarija Margan (Croatia)

Florin Gorunescu (Romania)

Elena Nechita (Romania)

Veska Georgieva (Bulgaria)

Bentaleb Najib (Morocco)

Zahraa Noureddine (Lebanon)

Zoran Dogas (Croatia

Manana Beruchashvili (Georgia)

Vesna Ilakovac (Croatia)

Aziz El Matri (Tunisia)

Raouf Alami (Morocco)

Samir Kaddar (Belgium)

Yamna Ettarres (Tunisia)

Mohamed Roushdy (Egypt)

Nabiha Kamal (Morocco)

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Essam Ayad (Egypt)

Simion Pruna (Romania)

Francesco Santocono (Italy)

Valérie Monfort (France)

Najla Triki (Tunisia)

Alda Kika (Albania)

Giuseppe De Pietro (Italy)

Sana Daya Marini (Lebanon)

Immacolata Pannone (Italy)

Asma H Sbeih (Palestine)

El Ouazzani Rajae (Morocco)

Simion Pruna (Romania)

Sami Turki (Tunisia)

Mohamed Roushdy (Egypt)

Ioana Moisil (Romania)

Oswaldo Trelles (Spain)

Iman Osta (Lebanon)

Andrei Selkov (Russia)

Valery Stolyar (Russia)

Nikolay Tverdokhlebov (Russia)

Leonid Godlevsky (Ukraine)

Tatjana Zrimec (Slovenia)

Abdellah Yousfi (Morocco)

Mustapha Belkasmi (Morocco)

El Kafil Abderrahman (Morocco) Mohamed Atounti (Morocco)

Chetouani Abdelaziz (Morocco)

Hassan Satori (Morocco)

Kaoutar LAMRINI UAHABI (Morocco)

Kawtar Slimani (Morocco)

Yahya Tayalati (Morocco)

Zolfo Maria (Belgium)

Souilmi Yassine (Morocco)

Okba Kazar (Algeria)

Claudio Azzolini (Italy)

Themis Exarchos (Greece)

Tomaz Amon (Slovenia)

Dimitris Fotiadis (Greece)

Anton Vladzymyrsky (Ukraine)

Souad Chaqsar (Morocco)

Tazi Abdelaziz (Morocco)

Fatima Gaboun (Morocco)

Mohammed Bennani (Morocco)

Said Boujraf (Morocco)

Mina Abaacrouche (Morocco)

Fatima Eddaoudi (Morocco)

Safae Nassiri (Morocco)

Abderrahman EL KHARRIM (Morocco)

Ghazal Hassan

Marzouki Kamal

Atounti Mohammed

Bargach Mounir

Chaabi Saad

Khattabi Asmae

Hjiaj Salim

Look Brahim

Samtal Chaimae

Sedrati Hayat

Elammari Leila

Hrich Ilyas

Souilmi Yassine

Hannaoui Abdellatif

Tariq Abdelkrim

Elouahabi Safae

Alaoui Ismaili Mustapha

Ganetri Ikram

Quechqar Ahmed

Sahar Elkasmi

Essayeh Soumia

Allali Imane

Chajai Salim

Bentounsi Zineb

Kaoutar LAMRINI UAHABI

Moutchou Karim

Touzani Rachid

Organizing Committee

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Partners EURO-MEDITERRANEAN MEDICAL INFORMATICS & TELEMEDICINE-EMMIT POLYDISCIPLINARY FACULTY OF NADOR – FPN NATIONAL SCHOOL PUBLIC HEALTH – ENSP US NATIONAL LIBRARY OF MEDICINE – NLM INTERNATIONAL INSTITUTE FOR TELEMEDICINE – IITM MOROCCAN SOCIETY FOR TELEMEDICINE & EHEALTH – MSFTEH INTERNATIONAL SOCIETY FOR TELEMEDICINE & EHEALTH – ISFTEH AMERICAN UNIVERSITY OF LEADERSHIP MOROCCO FOUNDATION – AULMF FACULTY OF MEDICINE & PHARMACY OF FES – FMPF FACULTY OF SCIENCES OF OUJDA – FSO ASSOCIATION MAROCAINE INFORMATIQUE MEDICALE -SMIM MED’OCIATION – RABAT INTERNATIONAL FEDERATION OF MEDICAL STUDENTS ASSOCIATIONS-MOROCCO MOROCCAN MEDICAL DOCTORS ABROAD ASSOCIATION OBSERVATORY CULTURAL AUDIOVISUAL COMMUNICATION IN THE MEDITERRANEA – OCCAM H3 AFRICAN BIOINFORMATICS NETWORK – H3ABIONET H3 AFRICA ISCB-REGIONAL STUDENT GROUP NORTHERN AFRICA – ISCB-RSG-NA MOROCCAN ARTIFICIAL INTELLIGENCE & MEDTECH COMMUNITY – MAIMC

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Sponsors US National Library of Medicine

Polydisciplinary Faculty of Nador

National School of Public Health

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Partners The International Society for Telemedicine & eHealth – ISfTeH

H3 Africa

GNU health Solidario

Faculty of Medicine of Fes

H3AbioNet

Compétences Médicales des Association of Moroccan

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The Moroccan Society for Telemedicine & eHealth

US National Library of Medicine

The Faculty of Sciences of Oujda – FSO

American University of Leadership Morocco Foundation AULMF

International Institute of Telemedicine

Observatory for Cultural Communication & Audiovisual Med- OCCAM

The Euromeditterranean Medical Informatics and Telemedicine Association -

Moroccan Society For Medical Informatics and Healthy

Artificial Intelligence and Knowledge Engineering Research Labs

ISCB-Regional Student Group Northern Africa Council – ISCB-RSG-NA

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International Federation of Medical Students Associations Morocco – IFMSA

Med ociation - Rabat

Moroccan Artificial Intelligence & Medtech Community – MAIMC