Analogic Scale (VAS) the intensity of heat or burning sensation; 0 no sensation, ... burning sensation statistically higher that the healthy controls (7.5 vs.
O12 PROSTATITIS AND PROSTATODYNIA Friday, 7 April, 14.00-15.30, Room Blue / Level 2 901 HEAT/BURNING SENSATION INDUCED BY TOPICAL APPLICATION OF CAPSAICIN ON THE PERINEAL CUTANEOUS AREA: A NEW APPROACH IN THE DIAGNOSIS AND TREATMENT OF CHRONIC PROSTATITICS/CHRONIC PELVIC PAIN SYNDROME (CP/CPPS)? Turini D.1, Lazzeri M.1, Beneforti P.1, Spinelli M.2, Malaguti S.2 University, Urology, Florence, Italy, 2Hospital, Spinal Unit, Milan, Italy
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INTRODUCTION & OBJECTIVES: To investigate the feasibility, the safety and the efficacy of perineal cutaneous application of capsaicin as a test for the diagnosis as well as potential therapeutic tool in patients with chronic prostatitis/ chronic pelvis pain syndrome (CP/CPPS). MATERIAL & METHODS: The study recruited 22 patients (mean age 34.5 yrs, range 19 -56), who had received the diagnosis of CP/CPPS according the NIH criteria and 6 healthy control subjects. Both the groups received a topical application of 5 ml of capsaicin at the concentration of 10-5M in the perineal body skin by sponge kept in situ by patient digital compression for 5 min. The same procedure was repeated in other three sites of the body: right hypochondrium, precordial area and hypogastric area. The patients were asked to mark in a Visual Analogic Scale (VAS) the intensity of heat or burning sensation; 0 no sensation, 10 the maximum heat/burning sensation experienced. All the patients completed a NIH- Chronic prostatitis symptom index (NIH-CPSI) before and one week the test. The scores of the two groups were compared using the Mann-Whitney-U test. RESULTS: The patients belonged to CP/CPPS reported an intensity of heat/ burning sensation statistically higher that the healthy controls (7.5 vs. 4.3 p
