RESEARCH ARTICLE
Helicobacter pylori Eradication Prevents Metachronous Gastric Neoplasms after Endoscopic Resection of Gastric Dysplasia Seung Hwan Shin1, Da Hyun Jung1*, Jie-Hyun Kim2, Hyun Soo Chung1, Jun Chul Park1, Sung Kwan Shin1, Sang Kil Lee1, Yong Chan Lee1 1 Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, 2 Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea *
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Abstract Purpose OPEN ACCESS Citation: Shin SH, Jung DH, Kim J-H, Chung HS, Park JC, Shin SK, et al. (2015) Helicobacter pylori Eradication Prevents Metachronous Gastric Neoplasms after Endoscopic Resection of Gastric Dysplasia. PLoS ONE 10(11): e0143257. doi:10.1371/journal.pone.0143257 Editor: Masaru Katoh, National Cancer Center, JAPAN Received: August 13, 2015 Accepted: November 2, 2015
There is insufficient data about the role of eradication of H. pylori after endoscopic resection (ER) for gastric dysplasia. The aim was to investigate the benefit of H. pylori eradication after ER in patients with gastric dysplasia to prevent metachronous gastric neoplasms.
Materials and Methods We retrospectively reviewed 1872 patients who underwent ER of gastric dysplasia. We excluded patients with a follow-up period of
