Feb 23, 2011 - Key Words: High gestational weight gain, preterm birth, low birth weight, systematic review, meta-analysis. Competing Interests: None declared ...
Obstetrics
High Gestational Weight Gain and the Risk of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis Sarah D. McDonald, MD, MSc,1,2,3,4 Zhen Han, MD, PhD,5 Sohail Mulla,6 Olha Lutsiv,6 Tiffany Lee,6 Joseph Beyene, PhD4; on behalf of the Knowledge Synthesis Group7 1
Division of Maternal-Fetal Medicine, McMaster University, Hamilton ON
2
Department of Obstetrics and Gynecology, McMaster University, Hamilton ON
3
Department of Radiology, McMaster University, Hamilton ON
4
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton ON
5
Department of Obstetrics and Gynecology, First Affiliated Hospital of Xi’an Jiao Tong University, Shaanxi Province, People’s Republic of China
6
Faculty of Health Sciences, McMaster University, Hamilton ON
7
See Appendix
Abstract Objective: Many women have high gestational weight gain (GWG), but potential neonatal consequences are not yet well quantified. We sought to determine the relationship between high GWG and preterm birth (PTB) and low birth weight (LBW) in singleton births. Data Sources: We searched Medline and Embase and reference lists. Study Selection: Two assessors independently performed all steps. We selected studies assessing high total or weekly GWG on PTB (
