in Girls with Turner's Syndrome

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symptoms in girls with Turner's syndrome (TS) ... Eleven girls with TS, 9-17 years of age, all,with ..... Downey J, Ehrhardt AA, Gruen R, Bell JJ, Morishima.
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Publishing House Ltd., London

Journal of Pediatric Endocrinology & Metabolism, l E, l 1 l l - l l l 7 (2005)

Depression, Levels of Anxiety and Self-Concept in Girls with Turner's Syndrome Birim G. Kıhçl, Ayça T. E eü'and Gönül Öcal2 of Child and Adolescent Psychiatry andzDivision of Pediatric Endocrinologl, Departmİnt of Pediatrics, Ankgra UniversiŞ School of Medicine, Anlrnra, TurkeY

1Department

ABsTRACT Self-esteem, depressive symptoms and anxiety

symptoms in girls with Turner's syndrome (TS)

were compared to those in girls with familial short stature (FSS) and healthy controls §C). Eleven girls with TS, 9-17 years of age, all,with 45,X0 karyotype, who were matched with 11 girls with FSS and 11 NC girls who had similar socio-demographic characteristics, were enrolled in the study. The Children's l)epression Inventoıy (CDD, State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self Concept Scale (PHSCS) were used to as§e§§ the extent of depression, anxiety and self reported self-esteem. The PHSCS means and standard deviations of the TS, F'SS and NC group§ were 56.2 + 6.71 62.7 + 6.9, and 69.3 + 6.0, and the STAIC-state anxiety means and standard deviations were 30.6 + 4.5, 23.3 + 6.1, and 25.7 + 3,7, respective§. Study findings showed that girls with TS had lower self-esteem and higher state anxiety levels than NC (p 0.05).

Significant differences were found in height and

HISDS between the groups. (Kruskal-Wallis test; f : |5.96,p:0.0001, arrdt:27.24,p = 0.000l, respectively). The Mann-Whitney U test indicated that significant height differences were present in the TS group versus the NC group (Z = -3,45,p: 0.001) and the FSS group versus the NC group (Z: -3.|2, p : 0.002). HtSDS was evaluated by pair group comparisons and significant differences were observed between groups TS and FSS, TS and NC, and FSS and NC (p 0.05). The CDI screens depressive symptoms and grades symptom severity in 27 items Girls VoLUME l8, No. l l,

with TS showed more depressive symptoms at a subsyndtomal level compared to girls in the other two groups. While six girls with TS reported unsatisfactory peer relationships, only two girls in the FSS gıoup and none in the NC group reported thus. Eight girls in the TS group versus two girls in the FSS group and one girl in the NC group complained of academic underachievement. Three girls in the TS group and two girls in the FSS group reported suicidal ideation. Although there was no significant difference between the groups in the CDI, one patient in the TS group fulfilled the DSMIV diagnostic criteria of a major depressive disorderl7 and one patient in the FSS group was diagnosed with attention deficit hyperactivity disorderı7. PHSCS scores showed a significant difference between groups Q( : |3.59, p : 0.00l).

STAIC-state anxiety scores were also significant at the level of 0.05 (see Table 3). The origin ofthe differences ofthe scale scores between groups was investigated using the MannWhitney U test (see Table 4). It was observed that there was a signifıcant difference between the TS group and the NC group in PHSCS and STAICstate anxiety scores (p