increased Lamlnin Concentrations In Serum in ... - Clinical Chemistry

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Wako UV Colorlmetrlc Pancreatic Lipase Assay wIth. 1,2-Dlilnoieoylglycerol as Substrate Evaluated, Johan. H. Robbrecht, Marc L. De Buyzere, and Joris R.

(blue spots on a white background). Finally, staining by immersion is preferable to spraying, being simpler, more uniform, and less hazardous to health. Although we used this staining method for one-dimensional TLC, obviously it can be applied more broadly. References 1. Vaskovsky YE. Phospholipid spray reagents. J Chromatogr 1972;65:447-50. 2. Vaskovsky VE. A universal reagentfor phospholipidanalysis.J Chromatogr 1975;114:129-41. 3. Parada 0. Fosfatidil glicerol y madurez pulmonar fetal. Obstet Ginecol Lat Am 1983;Sept-Oct:404-ll.

increased Lamlnin Concentrations In Serum in Hyperthyroidism, J. Kropf, A. M. Gressner, and K. Joseph (Dept. of Clin. Chem. and Central Lab., and Dept. of Clin. Nuclear Med., Klimkum der Philipps Universitat, Baldingerstrafle, D-3550 Marburg, F.R.G.) Concentrations of laniinin, a main constituent of basement membranes, in serum are significantly increased in patients with chronic active liver disease, rheumatoid arthritis, tumors, and diabetes. We have now investigated laminin in sera ofhyperthyroid patients, because a report (1) noted increased concentrations of the aminoterminal propeptide oftype Ill procollagen (PIJINP), another connective-tissue-derived component, in serum of hyperthyroid patients.

We determined laminin, triiodothyronine, thyroxin, free thyroxin (F#{149}F4), and thyrotropin (TSH) in sera from 42 patients with hyperthyroidism. Compared with a healthy reference population (n = 146, mean ± SD: 1.06 ± 0.15 kilo-arb. units/L), concentrations of laminin in serum of hyperthyroid patients (1.56 ± 0.33 kilo-arb. unitsfL) were significantly increased (P

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