increased plasma and liver lipids in streptozotocin-induced diabetic rats

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SUMMARY. The effects of incorporating cyanoglucoside extracts from yam or dasheen into the diet of streptozotocin-induced diabetic. Wistar rats were studiedĀ ...
Department of Basic Biomedical Sciences, Biochemistry Section, University of the West Indies, Mona, Kingston 7, Jamaica

Scientific Paper

INCREASED PLASMA AND LIVER LIPIDS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS: EFFECTS OF YAM (DIOSCOREA CAYENENSIS) OR DASHEEN (COLOCASSIA ESCULENTA) EXTRACT SUPPLEMENTS Felix O. Omoruyi, Phillip B. Grindley, Helen N. Asemota, Errol Y. St. A. Morrison

Key words: cyanoglucoside, lipid, yam, dasheen, diabetes

SUMMARY The effects of incorporating cyanoglucoside extracts from yam or dasheen into the diet of streptozotocin-induced diabetic Wistar rats were studied for four weeks. Intestinal lipase activity, and plasma glucose and lipid levels were determined. Also, liver total lipids, activities of ATP citrate lyase, pyruvate kinase and 6-phosphogluconate dehydrogenase were assessed. Dasheen extract significantly lowered plasma levels of glucose and triglycerides (p