Late Gadolinium Enhancement in Cardiac MRI in Patients with Severe

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the development of cardiac magnetic resonance imaging (CMR), it was seen ..... thy,26-28) and hypertrophic cardiomyopathy,29) as well as myocardial fibrosis.

Original Article http://dx.doi.org/10.4070/kcj.2014.44.5.312 Print ISSN 1738-5520 • On-line ISSN 1738-5555

Korean Circulation Journal

Late Gadolinium Enhancement in Cardiac MRI in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Systolic Function Is Related to Attenuated Improvement of Left Ventricular Geometry and Filling Pressure after Aortic Valve Replacement Junbeom Park, MD1, Hyuk-Jae Chang, MD1,2, Jung-Ho Choi, MD1, Pil-Sung Yang, MD1, Sang-Eun Lee, MD1, Ran Heo, MD1, Sanghoon Shin, MD1, In-Jeong Cho, MD1, Young-Jin Kim, MD1, Chi Young Shim, MD1, Geu-Ru Hong, MD1, and Namsik Chung, MD1 1

Division of Cardiology and Radiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Severance Biomedical Science Institute, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea

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Background and Objectives: We investigated echocardiographic predictors: left ventricular (LV) geometric changes following aortic valve replacement (AVR) according to the late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) in patients with severe aortic stenosis (AS) and preserved LV systolic function. Subjects and Methods: We analyzed 41 patients (24 males, 63.1±8.7 years) with preserved LV systolic function who were scheduled to undergo AVR for severe AS. All patients were examined with transthoracic echocardiography (TTE), CMR before and after AVR (in the hospital) and serial TTEs (at 6 and 12 months) were repeated. Results: The group with LGE (LGE+) showed greater wall thickness (septum, 14.3±2.6 mm vs. 11.5±2.0 mm, p=0.001, posterior; 14.3±2.5 mm vs. 11.4±1.6 mm, p

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