Letter TJH-2018-0089 Submitted: 9 March 2018 Accepted: 15 March 2018 Influenza A infection and stem cell mobilization
pr oo f
Sora Yasri KMT Primary care center, Bangkok Thailand bangkok 10340, Swaziland T: 6622578963 e-mail:
[email protected] ________________________________________ Sora Yasri KMT Primary care center, Bangkok Thailand , bangkok 10340, Swaziland
Viroj Wiwanitkit Wiwanitkit house, bangkhae, bangkok , bangkok 10160, Thailand
rre
ct
ed
Dear Editor, we read the publication entitled “Use of plerixafor to mobilize a healthy donor infected with influenza A” and found that it s very interesting [1]. Yeral et al. mentioned that “The effects of influenza A infection on stem cell mobilization are not know [1]” and concluded that “This report indicates that influenza A may suppress the hematopoietic system, negatively affecting stem cell mobilization. The problem may be overcome by plerixafor administration [1].” This article might give the new observation and confirm the usefulness of plerixafor in archiving stem cell mobilization. Nevertheless, it should note that this is no the first case of stem cell transplantation that the donor has influenza A infection. At least, Lee et al. reported the “stem cell transplantation from a related donor infected with influenza H1N1 2009” and the transplantation was completely done without the note of the problem of stem cell mobilization due to influenza virus [2]. In fact, regardless of using plerixafor, the stem cell transplantation in case that the donor has influenza infection is a big challenge and it is questionable that the procedure should be done or not.
un
co
References 1. Yeral M, Aytan P, Boğa C. Use of plerixafor to mobilize a healthy donor infected with influenza A. Turk J Haematol. 2018 Feb 2. doi: 10.4274/tjh.2017.0304. [Epub ahead of print] 2. Lee SH, Cheuh H, Yoo KH, Kim YJ, Sung KW, Koo HH, Kim DH, Kim SJ, Kim K, Jang JH, Jung CW. Hematopoietic stem cell transplantation from a related donor infected with influenza H1N1 2009. Transpl Infect Dis. 2011 Oct;13(5):548-50.
