Lung function growth an

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Apr 19, 2007 - Table 1 and E1 present the characteristics of the study population (n ..... p75. Adjust with O3 and NO2. PM10 (Boys). 2, 3. 2, 6. 2, 9. 3, 2. 1. 2. 3.
AJRCCM Articles in Press. Published on April 19, 2007 as doi:10.1164/rccm.200510-1678OC

Lung function growth in children with long-term exposure to air pollutants in Mexico City Running title: Lung function growth and air pollution

Rosalba Rojas-Martinez1, Rogelio Perez-Padilla2, Gustavo Olaiz-Fernandez1, Laura Mendoza-Alvarado1, Hortensia Moreno-Macias1,3, Teresa Fortoul4, William McDonnell5, Dana Loomis6, Isabelle Romieu1

1

Instituto Nacional de Salud Publica de México, México, 2 Instituto Nacional de

Enfermedades Respiratorias, México, 3Universidad Autónoma Metropolitana, México, 4

Mexico Medical School, UNAM, Mexico, 5Environmental Protection Agency, USA,

6

School of Public Health University of North Carolina, USA

Supported by the Mexican Sciences and Technology Council (CONACYT), SALUD-200501-13956, and the National Center for Environmental Health - Centers for Disease Control and Prevention, Atlanta GA, USA.

Correspondence and requests for reprints should be addressed to Dr. Isabelle Romieu, Instituto Nacional de Salud Publica, 655 Avenida Universidad, Col. Santa Maria Ahuacatitlán, Cuernavaca, Morelos 62508, México. Tel: 52-777-101-2935; fax: 52-777-3111148; e-mail: [email protected]

Category: 1.18 Air pollution This article has an online data supplement, which is accessible from this issue’s table of content online at www.atsjournals.org Word count: 2,583

Copyright (C) 2007 by the American Thoracic Society.

ABSTRACT Rationale: Although short-term exposure to air pollution has been associated with acute, reversible lung function decrements, the impact of long-term exposure has not been well established. Objective: To evaluate the association between long-term exposure to ozone (O3), particulate matter