can vary in zeaxanthin-biofortified and standard yellow sweet corn kernels by altering physiologic maturity of the cob and what part on the cob is selected.
EJO ISSN 1120-6721
Eur J Ophthalmol 2015; 25 (4): e59-e73 DOI: 10.5301/ejo.5000635
ABSTRACTS
Macular Carotenoids Conference 2015 Cambridge, UK - July 8-10, 2015 POSTER ABSTRACTS (MC001) NUTRITIONAL PATTERNS, MACULAR PIGMENT AND AGE-RELATED MACULAR DEGENERATION (AMD) IN THE PAMDI POPULATION OF THE MEDITERRANEAN BASIN Piermarocchi, R.1, Piermarocchi, S.1, Tognetto, D.1, Segato, T.2, Leung, I.3, Peto, T.3 1 University of Trieste, Trieste, Italy 2 University of Padua, Padua, Italy 3 NIHR BMRC at Moorfields Eye Hospital, NHS Foundation Trust, and UCL Institute of Ophthalmology, London, United Kingdom Purpose: To evaluate the association of nutritional patterns and macular pigment (MP) level with the prevalence of different severity grades of age-related macular degeneration (AMD) in a population of the Mediterranean basin. Methods: Food consumption data were collected at enrollment by using a food frequency questionnaire. Foods were grouped in 4 classes: protective (PF), risky (RF), lutein-rich (LR), and neutral (NF). Macular pigment (MP) level was measured by resonance Raman spectroscopy (RS) in a representative sample of 220 patients. Color fundus photography images were taken and graded for characteristics of AMD at the Moorfields Reading Centre. A multivariate logistic analysis evaluated the correlation of these factors with the different grades of AMD. Results: In the cohort of 824 patients, the intake of PF resulted in significant reduction in odds ratios for the development of large drusen (OR 0.95, CI 0.920.98, p = 0.008), more significantly so in the rural cohort (OR 0.93, CI 0.890.97, p = 0.0002). The 2 highest quartiles of PF and the 2 lowest of RF were associated with lower risk of large drusen (OR 0.72, CI 0.59-0.88, p = 0.0013; OR 1.23, CI 1.02-1.48, p = 0.0274, respectively). LR and NF were not associated with any stages of AMD. The mean level of MP was 955.1. There was a significant association between MP and the severity of the disease, especially in the advanced stages (p
