Mortality of patients with acute kidney injury requiring ...

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Original papers

Mortality of patients with acute kidney injury requiring renal replacement therapy Piotr Czempik1, C, D, Daniel Cieśla2, B, Piotr Knapik1, F, Łukasz Krzych1, A, E 1 2

Department of Cardiac Anesthesiology and Intensive Care, Silesian Centre for Heart Diseases, Zabrze, Poland Department of Science, Education and New Medical Technologies, Silesian Centre for Heart Diseases, Zabrze, Poland

A – research concept and design; B – collection and/or assembly of data; C – data analysis and interpretation; D – writing the article; E – critical revision of the article; F – final approval of the article

Advances in Clinical and Experimental Medicine, ISSN 1899–5276 (print), ISSN 2451–2680 (online)

Address for correspondence Piotr Czempik E-mail: [email protected]

Funding sources None declared

Conflict of interest None declared

Acknowledgements

We acknowledge the contribution made by departments that regularly report to the Silesian Registry of ICUs. Special thanks should be given to professors Hanna Misiołek and Dariusz Maciejewski, and to doctors Danuta Gierek, Agnieszka MisiewskaKaczur and Andrzej Moczała.

Received on April 30, 2016 Reviewed on June 19, 2016 Accepted on September 06, 2016

Adv Clin Exp Med. 2018;27(3):00–00

Abstract Background. Acute kidney injury (AKI) in critically ill patients has a deleterious impact on the prognosis, especially when renal replacement therapy (RRT) is required. This issue has not yet been investigated in the intensive care setting in Poland. Objectives. The aim of the study was to evaluate the short-term outcomes of AKI-RRT subjects, based on a large registry population. Material and methods. This observational multicenter study covered 100 demographic and clinical variables from the Silesian Registry of ICUs regarding 15,030 adult patients hospitalized between October 2011 and December 2014. The study group comprised 1,234 AKI individuals (8.2%) who required RRT. The primary outcome was ICU mortality. The length of ICU stay (LOS) was considered the secondary outcome. Observed mortality was compared to that predicted by the Acute Physiology and Chronic Health Evaluation II (APACHE II). Results. The overall mortality of the patients in the registry was 43.9%; it was higher in AKI-RRT subjects than in non-AKI-RRT counterparts (69.4% vs 41.0%; p