Patients sera was analized both by Multiplex technology using Bioplex 2200. (BioRad) and IIFA on Hep-2 cells (Inova). IIFA was considered positive for.
A NEW FORM OF ANTIPHOSPHOLIPID SYNDROME ASSOCIATED TO CHRONIC KIDNEY DISEASE? M. Serrano1, J.A. Martinez-Flores1, D. Perez Mendez2, C.M. Oscar3, M. Sevilla4, F. Garcia5, E. Gonzalez5, E. Paz-Artal4, J.M. Morales6, A. Serrano2 1
Instituto de Investigación Hospital Universitario 12 de Octubre, Immunology, Madrid, Spain Hospital Universitario 12 de Octubre, Immunology, Madrid, Spain 3 Hospital Universidad 12 de Octubre, Immunology, Madrid, Spain 4 Hospital 12 de OCtubre, Immunology, Madrid, Spain 5 Hospital 12 de Octubre, Nephrology, Madrid, Spain 6 Instituto de Investigacion Hospital 12 de Octubre, Immunology, Madrid, Spain 2
Cardiovascular are the most common events in patients with CKD. In the recent years, IgA aB2GPI antibodies have increased its clinical importance in Antiphospholipid Syndrome (APS) in seronegative patients. APS and Chronic Kidney Disease (CKD) Patients with CKD have a high prevalence (> 30%) of IgA aB2GPI antibodies and incidence of thrombotic events. In a two years follow-up, 46% of patients positive for IgA aB2GPI developed thrombotic events compared with 12% in negative patients [OR 6.3; p
