Natural product chemistry. Dr J White. Identify different natural products.
Synthesise your own perfume ... with common fragrances. • Match the fragrance
to the ...
Natural product chemistry Identify different natural products Synthesise your own perfume
Dr J White
• What is your impression of a chemist? • Write down one job that a chemist does?
Natural products • What are they? • Chemicals found in living things
• Where can you find them?
• What can you do with them?
Where can you find them? • Plants (spearmint), animals, bacteria
carvone
Marine Natural products • Gorgonian octacoral • Octalactin A
How do you get them?
What you do with them? Pharmaceuticals
Food additives
Fragrances
Task • Here are a mixture of natural products with common fragrances • Match the fragrance to the natural product
What does the organic chemist do? • Marine life have only a small amount of the active component. • Pharmaceutical companies want to make these compounds – Big scale – Cheap – Safe – Improve on nature
Building • We have to look at the target structure and create a strategy to build it. • Check our big recipe book of reactions • Building a car or baking a cake.
Task • Watch video clip from bbc senses • http://www.youtube.com/watch?v=7jYtpOlKs TI • How bad was the smell? • We will make our own brand of fragrance
What you have to do • • • • • • •
Safety Wear gloves & safety glasses Mix different ratios of base notes least fragrance Middle notes Top notes most volatile We will judge how good the fragrance is.
