NATURALLY OCCURRING BENZODIAZEPINES Structure ... - GBV

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NATURALLY OCCURRING. BENZODIAZEPINES. Structure, Distribution and. Function. Editors: IVAN IZQUIERDO,. Professor and Head of the Memory Centre,.
NATURALLY OCCURRING BENZODIAZEPINES Structure, Distribution and Function

Editors: IVAN IZQUIERDO, Professor and Head of the Memory Centre, Department of Biochemistry, Institute of Biosciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil and JORGE MEDINA, Laboratory of Neuroreceptors, Institute of Cell Biology, Faculty of Medicine, University of Buenos Aires, Argentina

ELLIS HORWOOD NEW YORK LONDON TORONTO SYDNEY TOKYO SINGAPORE

(Am)

Table of contents Preface 1. Benzodiazepines and benzodiazepine-like molecules are present in brain Angel Luis de Bias 2. Occurrence of benzodiazepine, benzodiazepine-like molecules and other ligands for the benzodiazepine receptor in nature J. H. Medina and A. C. Paladini 3. Origin of brain benzodiazepine and benzodiazepine-like molecules A. C. Paladini and J. H. Medina 4. Neurotransmitter systems involved in memory consolidation: the role of GABAA receptors I. Izquierdo

vii 1

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5. Endogenous benzodiazepine-like molecules and memory regulation I. Izquierdo

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6. Anxiety and brain benzodiazepine-like molecules C. Da Cunha, C. Wolfman, I. Izquierdo, and J. H. Medina

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7. The role of benzodiazepine receptor ligands in the pathogenesis of hepatic encephalopathy A. S. Basile 8 Endozepines: non-benzodiazepine endogenous allosteric modulators of GABAA receptors J. D. Rothstein and A. Guidotti i

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vi Table of contents 9.

Naturally occurring benzodiazepines: where we stand and where we go from here A. C. Paladini, J. H. Medina, and I. Izquierdo

Index

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