Neoadjuvant chemotherapy followed by concurrent ...

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2, Zhijun Duan, M.D. 3, Fei Han, M.D. 1, Junfang Liao M.D. 1, Meiling Deng, M.D. 1,. Terence T. Sio, M.D., M.S. 4, Anussara Prayongrat, M.D.5, Lie Zheng, M.D. 2 ...
Title: Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients with cervical nodal necrosis Author list: Mei Lan, M.D. †1, Chunyan Chen, M.D. †1, Ying Huang, M.D. 1 , Li Tian, M.D. 2, Zhijun Duan, M.D. 3, Fei Han, M.D. 1, Junfang Liao M.D. 1, Meiling Deng, M.D. 1, Terence T. Sio, M.D., M.S. 4, Anussara Prayongrat, M.D.5, Lie Zheng, M.D. 2, Shaoxiong Wu, M.D. *1 , Taixiang Lu, M.D* 1.

Supplementary Table. Univariate predictors of disease-specific survival , disease-free survival, regional recurrence-free survival and distant metastasis-free survival in the propensity-matched cohort of 508 patients. Characteristic N (%) 5y-DSS P value* 5y-DFS P value* 5y-RRFS P value* 5y-DMFS P value* Gender Male Female Age(years) ≤44 >44 T stage T1 T2 T3 T4 N stage N1 N2 N3 Clinical stage II III IV Treatment NACT+CCRT CCRT alone RT technique IMRT 2DRT/3DCRT

0.007 381(75.0) 127(25.0)

73.8 87.7

0.029 59.1 71.4

0.01 278(54.7) 230(45.3)

81.7 71.9

61.4 63.6

82.1 82.9 79.1 69.1 81.8 73.7 77.1

23(4.5) 184(36.2) 301(59.3)

86.7 82.5 73.5

254(50.0) 254(50.0)

82.1 72.5

232(45.7) 276(54.3)

74.9 79.6

0.075 85.9 78.3 71.6

0.053 94.3 89.6

0.666 60.6 63.7

77.3 72.1 74.3

88.9 91.5 94.6

70.3 54.1

0.521

0.547