Neurobiology. Cannabis and psychosis

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Umut Kırlı¹*, Hayriye Elbi¹, Tolga Binbay ², Köksal Alptekin², Bülent Kayahan¹, Nesli Zağlı³, Hüseyin Onay 4, Ferda Özkınay4 , Duygu Keskin¹, Kübra Yıldırım³, Jim ...
Quitting cannabis decreases but does not eliminate psychosis risk: Evidence from a 7 years large general population-based cohort Umut Kırlı¹*, Hayriye Elbi¹, Tolga Binbay ², Köksal Alptekin², Bülent Kayahan¹, Nesli Zağlı³, Hüseyin Onay 4, Ferda Özkınay 4 , Duygu Keskin¹, Kübra Yıldırım³, Jim van Os5 ¹ Ege University School of Medicine Department of Psychiatry, Izmir; ² Dokuz Eylul University School of Medicine Department of Psychiatry, Izmir Turkey; ³ Dokuz Eylul University Institute of Health Sciences Department of Neuroscience, Izmir, Turkey; 4 Ege University School of Medicine Department of Medical Genetics, Izmir,Turkey 5Maastricht University Medical Centre School of Mental Health and Neuroscience, Maastricht, The Netherlands * [email protected]

Introduction Introduction

Results

• The use of cannabis is consistently associated with psychotic disorders (1).

Table 1: Relation between continuum properties of cannabis use throughout follow-up and newly onset psychotic disorder diagnosed at T1.

• However we have less information about the longitudinal psychotic

Cannabis Use At Least Five Times In Total

OR

%95 GA

Never

ref

-

T0 (+), T1 (+)

33,2

(6,1-181,6)