Pediatric Norovirus Diarrhea in Nicaragua - Journal of Clinical ...

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Mar 14, 2008 - JOURNAL OF CLINICAL MICROBIOLOGY, Aug. 2008, p. 2573–2580 ...... Global illness and deaths caused by rotavirus disease in chil- dren.
JOURNAL OF CLINICAL MICROBIOLOGY, Aug. 2008, p. 2573–2580 0095-1137/08/$08.00⫹0 doi:10.1128/JCM.00505-08 Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Vol. 46, No. 8

Pediatric Norovirus Diarrhea in Nicaragua䌤 Filemon Bucardo,1,2,3 Johan Nordgren,2,4 Beatrice Carlsson,2 Margarita Paniagua,1,3 Per-Eric Lindgren,4 Felix Espinoza,1 and Lennart Svensson2* Department of Microbiology, University of Leo ´n, UNAN-Leo ´n, Nicaragua1; Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linko ¨ping University, Linko ¨ping, Sweden2; Microbiology, Tumor and Cell Biology Centre, Karolinska Institutet, S-171 77 Stockholm, Sweden3; and Division of Medical Microbiology, Department of Clinical and Experimental Medicine, Linko ¨ping University, Linko ¨ping, Sweden4 Received 14 March 2008/Returned for modification 17 April 2008/Accepted 6 June 2008

Information about norovirus (NoV) infections in Central America is limited. Through a passive community and hospital pediatric diarrhea surveillance program, a total of 542 stool samples were collected between March 2005 and February 2006 in Leo ´n, Nicaragua. NoV was detected in 12% (65/542) of the children; of these, 11% (45/409) were in the community and 15% (20/133) were in the hospital, with most strains (88%) belonging to genogroup II. NoV infections were age and gender associated, with children of