Home
Add Document
Sign In
Create An Account
Pharmacotherapy - Tufts OpenCourseWare - Tufts University
Recommend Documents
No documents
Pharmacotherapy - Tufts OpenCourseWare - Tufts University
Download PDF
19 downloads
202 Views
3MB Size
Report
Comment
Pharmacotherapy: opioids, NSAIDs, adjuvants, and analgesic e... 2. Pharmacotherapy of Pain. Tufts OpenCourseWare. © 2007 Tufts University.
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
1.
Pharmacotherapy: opioids, NSAIDs, adjuvants, and analgesic e...
2.
Pharmacotherapy of Pain
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 1
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
3.
Mechanisms of Pain and Medication Activity Sites
4.
Classes of analgesics
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 2
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
5.
Severity: WHO analgesic ladder
6.
Pain Source
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 3
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
7.
Acute vs. chronic therapy
8.
Acute vs. chronic therapy
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 4
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
9.
Elderly Patients
10.
Opioids
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 5
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
11.
Positioning Opioid Therapy
12.
Opioids: Mode of action
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 6
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
13.
Guidelines for Management of Opioid Therapy
14.
Opioid Agents
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 7
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
15.
Morphine
16.
When to consider alternatives to morphine?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 8
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
17.
When to consider alternatives to morphine?
18.
When to consider alternatives to morphine?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 9
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
19.
When to consider alternatives to morphine?
20.
When to consider alternatives to morphine?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 10
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
21.
When to consider alternatives to morphine?
22.
Transdermal Fentanyl
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 11
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
23.
Mixed Agonist-Antagonists/Partial agonists
24.
Antagonists
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 12
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
25.
Naloxone
26.
Medication Schedules
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 13
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
27.
Opioid Selection: Poor Choices for Chronic Pain
28.
Opioid-drug interactions
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 14
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
29.
Routes of Administration
30.
Opioid Therapy: Dosing Guidelines
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 15
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
31.
Opioid Therapy: Dosing Guidelines
32.
Poor Opioid Responsiveness
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 16
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
33.
Opioid Rotation
34.
How does this look?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 17
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
35.
Equianalgesic Conversion
36.
Tolerance
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 18
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
37.
Incomplete cross-tolerance
38.
Equianalgesic conversion
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 19
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
39.
Conversion Table
40.
Simple example
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 20
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
41.
Simple example cont.
42.
Equianalgesic conversion example
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 21
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
43.
Equianalgesic conversion example
44.
Equianalgesic conversion example
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 22
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
45.
Equianalgesic conversion example
46.
Equianalgesic conversion example
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 23
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
47.
Equianalgesic conversion example
48.
Equianalgesic conversion example
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 24
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
49.
Nonopioid Analgesics
50.
NSAIDs: Properties
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 25
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
51.
Non-opioid analgesics
52.
Non-opioid analgesics: WHO ladder
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 26
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
53.
Positioning NSAID Therapy
54.
Guidelines for Management of NSAID Therapy
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 27
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
55.
NSAID with or without opioid?
56.
NSAID with or without opioid?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 28
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
57.
NSAIDs - Adverse effects
58.
NSAIDs: drug interactions
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 29
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
59.
Which NSAID to choose?
60.
Which NSAID not to choose?
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 30
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
61.
NSAIDs: available agents
62.
NSAID Recommendations
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 31
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
63.
Coxibs - place in therapy
64.
Adjuvant Analgesics
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 32
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
65.
Adjuvant Analgesics
66.
Adjuvant Analgesics - place in therapy
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 33
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
67.
Adjuvant Analgesics
68.
Risk factors for herpes zoster
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 34
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
69.
Pharmacotherapy: Slide 69
70.
Anticonvulsants
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 35
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
71.
Gabapentin/Pregabalin
72.
Gabapentin
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 36
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
73.
Pregabalin
74.
Pregabalin
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 37
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
75.
Pregabalin in neuropathic pain
76.
Antidepressants
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 38
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
77.
Antidepressants
78.
Local anesthetics and oral analogues
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 39
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
79.
Steroids
80.
Alpha-2 adrenergic agonists
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 40
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
81.
NMDA-receptor antagonists
82.
Topical Analgesics/Anesthetics
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 41
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
83.
“Muscle relaxants”
84.
Miscellaneous drugs
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 42
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
85.
Adjuvant Analgesics for Cancer Pain
86.
First-line medications for neuropathic pain
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 43
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
87.
Add the following?
88.
Treatment Options
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 44
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
89.
Summary
90.
Summary
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 45
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
91.
NSAIDs: Summary
92.
Summary
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Page - 46
Tufts OpenCourseWare
© 2007 Tufts University
Pharmacotherapy
93.
OCW: Introduction to Clinical Pain Problems (E. McNicol)
Pharmacotherapy: Slide 93
Page - 47
×
Report "Pharmacotherapy - Tufts OpenCourseWare - Tufts University"
Your name
Email
Reason
-Select Reason-
Pornographic
Defamatory
Illegal/Unlawful
Spam
Other Terms Of Service Violation
File a copyright complaint
Description
×
Sign In
Email
Password
Remember me
Forgot password?
Sign In
Our partners will collect data and use cookies for ad personalization and measurement.
Learn how we and our ad partner Google, collect and use data
.
Agree & close